inner acrosomal membrane Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description The acrosomal membrane region that underlies the acrosomal vesicle and is located toward the sperm nucleus. This region is responsible for molecular interactions allowing the sperm to penetrate the zona pellucida and fuses with the egg plasma membrane. (Gene Ontology, GO_0002079)
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48 proteins co-occuring with the inner acrosomal membrane cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
SPAM1 sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding) 2.14205
CD46 CD46 molecule, complement regulatory protein 1.87451
ACR acrosin 1.76626
SPACA1 sperm acrosome associated 1 1.48701
ADM adrenomedullin 1.38073
ACRV1 acrosomal vesicle protein 1 1.35978
TMEM190 transmembrane protein 190 1.11225
CALCRL calcitonin receptor-like 1.10409
SPACA4 sperm acrosome associated 4 1.07866
RAMP2 receptor (G protein-coupled) activity modifying protein 2 1.05993
PSMD8 proteasome (prosome, macropain) 26S subunit, non-ATPase, 8 1.00202
MSH6 mutS homolog 6 0.995632
ZP3 zona pellucida glycoprotein 3 (sperm receptor) 0.990247
ZP2 zona pellucida glycoprotein 2 (sperm receptor) 0.97323
RAMP1 receptor (G protein-coupled) activity modifying protein 1 0.745025
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 0.70439
ZAN zonadhesin (gene/pseudogene) 0.673762
ZPBP zona pellucida binding protein 0.668126
IZUMO1 izumo sperm-egg fusion 1 0.65905
CD59 CD59 molecule, complement regulatory protein 0.656464
PHB2 prohibitin 2 0.592652
CREB3L4 cAMP responsive element binding protein 3-like 4 0.570496
PLA2G5 phospholipase A2, group V 0.566754
RAMP3 receptor (G protein-coupled) activity modifying protein 3 0.535361
ZNF77 zinc finger protein 77 0.518573
ARSA arylsulfatase A 0.459203
NPTXR neuronal pentraxin receptor 0.41221
PLAUR plasminogen activator, urokinase receptor 0.409869
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) 0.386979
PRIMA1 proline rich membrane anchor 1 0.382739
CD9 CD9 molecule 0.371599
HSPA1B heat shock 70kDa protein 1B 0.343421
CKB creatine kinase, brain 0.321201
MLPH melanophilin 0.303655
PSMD4 proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 0.277774
RPE65 retinal pigment epithelium-specific protein 65kDa 0.255107
TBX1 T-box 1 0.240276
CDIPT CDP-diacylglycerol--inositol 3-phosphatidyltransferase 0.224204
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase 0.22385
HSPA1A heat shock 70kDa protein 1A 0.22385
CALCA calcitonin-related polypeptide alpha 0.217511
SGK1 serum/glucocorticoid regulated kinase 1 0.206423
CKM creatine kinase, muscle 0.183935
PGRMC1 progesterone receptor membrane component 1 0.183328
ALLC allantoicase 0.17687
CAMP cathelicidin antimicrobial peptide 0.172735
FTL ferritin, light polypeptide 0.172468
FTH1 ferritin, heavy polypeptide 1 0.17141