insr Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description insulin receptor|After removal of the precursor signal peptide, the insulin receptor precursor is post-translationally cleaved into two chains (alpha and beta) that are covalently linked. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 3643)
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Genes

19 genes co-occuring with the biological term insr in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ACSL1 acyl-CoA synthetase long-chain family member 1
CALR calreticulin
CCDC8 coiled-coil domain containing 8
CHN2 chimerin 2
CPT1A carnitine palmitoyltransferase 1A (liver)
CUL7 cullin 7
ERN1 endoplasmic reticulum to nucleus signaling 1
FABP2 fatty acid binding protein 2, intestinal
GNB3 guanine nucleotide binding protein (G protein), beta polypeptide 3
IGF1R insulin-like growth factor 1 receptor
IGF2 insulin-like growth factor 2
INS insulin
INSR insulin receptor
IRS1 insulin receptor substrate 1
IRS2 insulin receptor substrate 2
LEPR leptin receptor
NPC1 Niemann-Pick disease, type C1
OBSL1 obscurin-like 1
PKD1 polycystic kidney disease 1 (autosomal dominant)