insulin-resistant diabetes mellitus Gene Set

Dataset HPO Gene-Disease Associations
Category disease or phenotype associations
Type phenotype
Description A type of diabetes mellitus related not to lack of insulin but rather to lack of response to insulin on the part of the target tissues of insulin such as muscle, fat, and liver cells. This type of diabetes is typically associated with increases both in blood glucose concentrations as will as in fasting and postprandial serum insulin levels. (Human Phenotype Ontology, HP_0000831)
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13 genes associated with the insulin-resistant diabetes mellitus phenotype by mapping known disease genes to disease phenotypes from the HPO Gene-Disease Associations dataset.

Symbol Name
ABCC8 ATP-binding cassette, sub-family C (CFTR/MRP), member 8
AGPAT2 1-acylglycerol-3-phosphate O-acyltransferase 2
ALMS1 Alstrom syndrome protein 1
BSCL2 Berardinelli-Seip congenital lipodystrophy 2 (seipin)
INSR insulin receptor
KCNJ11 potassium channel, inwardly rectifying subfamily J, member 11
LMNA lamin A/C
PDX1 pancreatic and duodenal homeobox 1
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PPARG peroxisome proliferator-activated receptor gamma
PPP1R3A protein phosphatase 1, regulatory subunit 3A
ZFP57 ZFP57 zinc finger protein
ZMPSTE24 zinc metallopeptidase STE24