insulinoma Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description A benign tumor of the PANCREATIC BETA CELLS. Insulinoma secretes excess INSULIN resulting in HYPOGLYCEMIA.|A usually benign, well circumscribed neoplasm arising from the beta cells of the pancreas. Patients exhibit symptoms related to hypoglycemia due to inappropriate secretion of insulin. (Experimental Factor Ontology, EFO_0000549)
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Genes

22 genes co-occuring with the biological term insulinoma in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit
CACNA1D calcium channel, voltage-dependent, L type, alpha 1D subunit
CD40 CD40 molecule, TNF receptor superfamily member 5
CD40LG CD40 ligand
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1
EPCAM epithelial cell adhesion molecule
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
GCG glucagon
GLP1R glucagon-like peptide 1 receptor
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2
IGFBP3 insulin-like growth factor binding protein 3
INS insulin
LANCL2 LanC lantibiotic synthetase component C-like 2 (bacterial)
LEP leptin
MAFA v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog A
MEN1 multiple endocrine neoplasia I
PDX1 pancreatic and duodenal homeobox 1
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PTPRN protein tyrosine phosphatase, receptor type, N
PTPRS protein tyrosine phosphatase, receptor type, S
SLC30A8 solute carrier family 30 (zinc transporter), member 8