insulitis Gene Set
Genes
22 gene mutations causing the insulitis phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.
| Symbol |
Name |
|
AIRE
|
autoimmune regulator
|
|
B2M
|
beta-2-microglobulin
|
|
CD38
|
CD38 molecule
|
|
CIITA
|
class II, major histocompatibility complex, transactivator
|
|
CTSB
|
cathepsin B
|
|
CTSS
|
cathepsin S
|
|
CTSV
|
cathepsin V
|
|
E2F1
|
E2F transcription factor 1
|
|
HLA-DQB1
|
major histocompatibility complex, class II, DQ beta 1
|
|
ICOS
|
inducible T-cell co-stimulator
|
|
IGHM
|
immunoglobulin heavy constant mu
|
|
IL4
|
interleukin 4
|
|
INS
|
insulin
|
|
MERTK
|
MER proto-oncogene, tyrosine kinase
|
|
MTUS1
|
microtubule associated tumor suppressor 1
|
|
PDCD1LG2
|
programmed cell death 1 ligand 2
|
|
PLA2G4A
|
phospholipase A2, group IVA (cytosolic, calcium-dependent)
|
|
PRF1
|
perforin 1 (pore forming protein)
|
|
PTPRN
|
protein tyrosine phosphatase, receptor type, N
|
|
RAPGEF3
|
Rap guanine nucleotide exchange factor (GEF) 3
|
|
TLR2
|
toll-like receptor 2
|
|
TNFRSF9
|
tumor necrosis factor receptor superfamily, member 9
|
