intact Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

415 genes co-occuring with the biological term intact in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
A2M alpha-2-macroglobulin
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ABCB4 ATP-binding cassette, sub-family B (MDR/TAP), member 4
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
ACE angiotensin I converting enzyme
ADAMTS4 ADAM metallopeptidase with thrombospondin type 1 motif, 4
ADIPOQ adiponectin, C1Q and collagen domain containing
ADM adrenomedullin
ADORA2A adenosine A2a receptor
ADRA1A adrenoceptor alpha 1A
ADRA1B adrenoceptor alpha 1B
ADRA1D adrenoceptor alpha 1D
ADRB2 adrenoceptor beta 2, surface
AICDA activation-induced cytidine deaminase
AKAP9 A kinase (PRKA) anchor protein 9
AKR1C3 aldo-keto reductase family 1, member C3
ALCAM activated leukocyte cell adhesion molecule
ALOX5 arachidonate 5-lipoxygenase
ALOX5AP arachidonate 5-lipoxygenase-activating protein
AMBP alpha-1-microglobulin/bikunin precursor
ANXA2 annexin A2
AP3M1 adaptor-related protein complex 3, mu 1 subunit
APBA2 amyloid beta (A4) precursor protein-binding, family A, member 2
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1
APOA1 apolipoprotein A-I
APOBEC3B apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B
APOBEC3C apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C
APOE apolipoprotein E
APOH apolipoprotein H (beta-2-glycoprotein I)
APP amyloid beta (A4) precursor protein
AQP1 aquaporin 1 (Colton blood group)
ARHGEF10L Rho guanine nucleotide exchange factor (GEF) 10-like
ARRB1 arrestin, beta 1
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1
ATP7B ATPase, Cu++ transporting, beta polypeptide
ATXN2 ataxin 2
AURKB aurora kinase B
AXIN1 axin 1
AZF1 azoospermia factor 1
BAX BCL2-associated X protein
BCAR4 breast cancer anti-estrogen resistance 4 (non-protein coding)
BCL2L1 BCL2-like 1
BDKRB2 bradykinin receptor B2
BGLAP bone gamma-carboxyglutamate (gla) protein
BIK BCL2-interacting killer (apoptosis-inducing)
BIN1 bridging integrator 1
BIRC5 baculoviral IAP repeat containing 5
BIRC7 baculoviral IAP repeat containing 7
BRAF B-Raf proto-oncogene, serine/threonine kinase
BRCA1 breast cancer 1, early onset
BRCA2 breast cancer 2, early onset
BRD4 bromodomain containing 4
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase
C2 complement component 2
CA9 carbonic anhydrase IX
CACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
CALM1 calmodulin 1 (phosphorylase kinase, delta)
CAMP cathelicidin antimicrobial peptide
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP6 caspase 6, apoptosis-related cysteine peptidase
CASP9 caspase 9, apoptosis-related cysteine peptidase
CASR calcium-sensing receptor
CAV1 caveolin 1, caveolae protein, 22kDa
CCL2 chemokine (C-C motif) ligand 2
CCND1 cyclin D1
CCR1 chemokine (C-C motif) receptor 1
CCR7 chemokine (C-C motif) receptor 7
CD14 CD14 molecule
CD4 CD4 molecule
CD40 CD40 molecule, TNF receptor superfamily member 5
CD40LG CD40 ligand
CD44 CD44 molecule (Indian blood group)
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
CD81 CD81 molecule
CDC25A cell division cycle 25A
CDCP1 CUB domain containing protein 1
CDK4 cyclin-dependent kinase 4
CDK7 cyclin-dependent kinase 7
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN2A cyclin-dependent kinase inhibitor 2A
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CFH complement factor H
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CGB chorionic gonadotropin, beta polypeptide
CHRNA7 cholinergic receptor, nicotinic, alpha 7 (neuronal)
CNGB1 cyclic nucleotide gated channel beta 1
CNN1 calponin 1, basic, smooth muscle
CNOT7 CCR4-NOT transcription complex, subunit 7
CNR1 cannabinoid receptor 1 (brain)
CPB2 carboxypeptidase B2 (plasma)
CRYAA crystallin, alpha A
CRYAB crystallin, alpha B
CRYBA1 crystallin, beta A1
CRYBB1 crystallin, beta B1
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTSG cathepsin G
CTTN cortactin
CUL1 cullin 1
CUL3 cullin 3
CUL5 cullin 5
CXCL8 chemokine (C-X-C motif) ligand 8
DAZ1 deleted in azoospermia 1
DCK deoxycytidine kinase
DCTN1 dynactin 1
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DGKA diacylglycerol kinase, alpha 80kDa
DICER1 dicer 1, ribonuclease type III
DIO3 deiodinase, iodothyronine, type III
DISC1 disrupted in schizophrenia 1
DKC1 dyskeratosis congenita 1, dyskerin
DKK1 dickkopf WNT signaling pathway inhibitor 1
DLAT dihydrolipoamide S-acetyltransferase
DMD dystrophin
DNM1L dynamin 1-like
DPP9 dipeptidyl-peptidase 9
DSCAM Down syndrome cell adhesion molecule
DSCAML1 Down syndrome cell adhesion molecule like 1
DVL3 dishevelled segment polarity protein 3
E2F5 E2F transcription factor 5, p130-binding
ECE2 endothelin converting enzyme 2
EGF epidermal growth factor
EGFR epidermal growth factor receptor
EGR1 early growth response 1
EGR4 early growth response 4
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific )
ELN elastin
EPB41 erythrocyte membrane protein band 4.1
EPHA4 EPH receptor A4
ESR1 estrogen receptor 1
ESRRA estrogen-related receptor alpha
F13A1 coagulation factor XIII, A1 polypeptide
F7 coagulation factor VII (serum prothrombin conversion accelerator)
F8 coagulation factor VIII, procoagulant component
F9 coagulation factor IX
FASN fatty acid synthase
FCGR3A Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
FCRL5 Fc receptor-like 5
FGA fibrinogen alpha chain
FGB fibrinogen beta chain
FGF19 fibroblast growth factor 19
FGF21 fibroblast growth factor 21
FGF23 fibroblast growth factor 23
FLT3 fms-related tyrosine kinase 3
FN3K fructosamine 3 kinase
FOLR1 folate receptor 1 (adult)
FOXP3 forkhead box P3
FRAT1 frequently rearranged in advanced T-cell lymphomas 1
GAL galanin/GMAP prepropeptide
GCG glucagon
GDF5 growth differentiation factor 5
GJA1 gap junction protein, alpha 1, 43kDa
GJA4 gap junction protein, alpha 4, 37kDa
GM2AP1 GM2 ganglioside activator pseudogene 1
GNAO1 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
GPER1 G protein-coupled estrogen receptor 1
GRB10 growth factor receptor-bound protein 10
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1
GRM1 glutamate receptor, metabotropic 1
GSK3B glycogen synthase kinase 3 beta
GTSE1 G-2 and S-phase expressed 1
GUCY1B3 guanylate cyclase 1, soluble, beta 3
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
H6PD hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
HBA1 hemoglobin, alpha 1
HBB hemoglobin, beta
HCN2 hyperpolarization activated cyclic nucleotide gated potassium channel 2
HCRT hypocretin (orexin) neuropeptide precursor
HDAC1 histone deacetylase 1
HDAC2 histone deacetylase 2
HEBP2 heme binding protein 2
HEPACAM hepatic and glial cell adhesion molecule
HMGA1 high mobility group AT-hook 1
HMOX1 heme oxygenase 1
HPSE heparanase
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1
HSD17B1 hydroxysteroid (17-beta) dehydrogenase 1
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
HTR1A 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled
ICAM1 intercellular adhesion molecule 1
IDE insulin-degrading enzyme
IDO1 indoleamine 2,3-dioxygenase 1
IFNA1 interferon, alpha 1
IFNG interferon, gamma
IFNGR1 interferon gamma receptor 1
IGF1R insulin-like growth factor 1 receptor
IGF2 insulin-like growth factor 2
IGF2R insulin-like growth factor 2 receptor
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IGFBP3 insulin-like growth factor binding protein 3
IGLC1 immunoglobulin lambda constant 1 (Mcg marker)
IL10 interleukin 10
IL12A interleukin 12A
IL12RB2 interleukin 12 receptor, beta 2
IL1RAPL1 interleukin 1 receptor accessory protein-like 1
IL1RN interleukin 1 receptor antagonist
IL2RA interleukin 2 receptor, alpha
IL6 interleukin 6
IL6R interleukin 6 receptor
INPPL1 inositol polyphosphate phosphatase-like 1
INS insulin
INSR insulin receptor
IQGAP1 IQ motif containing GTPase activating protein 1
IRAK3 interleukin-1 receptor-associated kinase 3
IREB2 iron-responsive element binding protein 2
ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
JAG1 jagged 1
JAK3 Janus kinase 3
KCNK3 potassium channel, two pore domain subfamily K, member 3
KCNQ1 potassium channel, voltage gated KQT-like subfamily Q, member 1
KDM1A lysine (K)-specific demethylase 1A
KDR kinase insert domain receptor
KHK ketohexokinase (fructokinase)
KISS1 KiSS-1 metastasis-suppressor
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KITLG KIT ligand
KL klotho
KLB klotho beta
KMT2A lysine (K)-specific methyltransferase 2A
KPNA1 karyopherin alpha 1 (importin alpha 5)
KPNB1 karyopherin (importin) beta 1
LCN2 lipocalin 2
LECT1 leukocyte cell derived chemotaxin 1
LEP leptin
LETM1 leucine zipper-EF-hand containing transmembrane protein 1
LMX1B LIM homeobox transcription factor 1, beta
LNPEP leucyl/cystinyl aminopeptidase
LRP1 low density lipoprotein receptor-related protein 1
LRRK2 leucine-rich repeat kinase 2
LTF lactotransferrin
MAP2K1 mitogen-activated protein kinase kinase 1
MAP2K4 mitogen-activated protein kinase kinase 4
MAPK1 mitogen-activated protein kinase 1
MAPK14 mitogen-activated protein kinase 14
MAPK3 mitogen-activated protein kinase 3
MAPK8 mitogen-activated protein kinase 8
MAPT microtubule-associated protein tau
MATN3 matrilin 3
MB myoglobin
MCPH1 microcephalin 1
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MECP2 methyl CpG binding protein 2
MIER1 mesoderm induction early response 1, transcriptional regulator
MIP major intrinsic protein of lens fiber
MIR122 microRNA 122
MIR200B microRNA 200b
MLLT1 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1
MMP2 matrix metallopeptidase 2
MMP8 matrix metallopeptidase 8
MMP9 matrix metallopeptidase 9
MPL MPL proto-oncogene, thrombopoietin receptor
MPO myeloperoxidase
MRE11A MRE11 meiotic recombination 11 homolog A (S. cerevisiae)
MSH2 mutS homolog 2
MSH6 mutS homolog 6
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MUC1 mucin 1, cell surface associated
MVK mevalonate kinase
MYD88 myeloid differentiation primary response 88
NAMPT nicotinamide phosphoribosyltransferase
NBN nibrin
NCF2 neutrophil cytosolic factor 2
NEUROG3 neurogenin 3
NHEJ1 nonhomologous end-joining factor 1
NLRC5 NLR family, CARD domain containing 5
NOD1 nucleotide-binding oligomerization domain containing 1
NOS2 nitric oxide synthase 2, inducible
NOTCH1 notch 1
NOX4 NADPH oxidase 4
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin)
NPR2 natriuretic peptide receptor 2
NPY neuropeptide Y
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NUMB numb homolog (Drosophila)
NUP62 nucleoporin 62kDa
OGT O-linked N-acetylglucosamine (GlcNAc) transferase
ORM1 orosomucoid 1
OXTR oxytocin receptor
P2RX2 purinergic receptor P2X, ligand gated ion channel, 2
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7
P2RY1 purinergic receptor P2Y, G-protein coupled, 1
P3H1 prolyl 3-hydroxylase 1
PANX1 pannexin 1
PANX3 pannexin 3
PDGFB platelet-derived growth factor beta polypeptide
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PLA2G2D phospholipase A2, group IID
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PLAUR plasminogen activator, urokinase receptor
PLD1 phospholipase D1, phosphatidylcholine-specific
PLD2 phospholipase D2
PLN phospholamban
PNLIP pancreatic lipase
PODXL podocalyxin-like
POMZP3 POM121 and ZP3 fusion
PON1 paraoxonase 1
PPARG peroxisome proliferator-activated receptor gamma
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
PPP1R2 protein phosphatase 1, regulatory (inhibitor) subunit 2
PRDX2 peroxiredoxin 2
PRDX6 peroxiredoxin 6
PRELID1 PRELI domain containing 1
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
PRNP prion protein
PSMC3 proteasome (prosome, macropain) 26S subunit, ATPase, 3
PSMD14 proteasome (prosome, macropain) 26S subunit, non-ATPase, 14
PTEN phosphatase and tensin homolog
PTH parathyroid hormone
PTPN6 protein tyrosine phosphatase, non-receptor type 6
PTPN9 protein tyrosine phosphatase, non-receptor type 9
PTPRJ protein tyrosine phosphatase, receptor type, J
RAD50 RAD50 homolog (S. cerevisiae)
RAD54L RAD54-like (S. cerevisiae)
RAE1 ribonucleic acid export 1
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RARRES3 retinoic acid receptor responder (tazarotene induced) 3
RB1 retinoblastoma 1
RCOR1 REST corepressor 1
RGS11 regulator of G-protein signaling 11
RGS7BP regulator of G-protein signaling 7 binding protein
RHAG Rh-associated glycoprotein
RHO rhodopsin
RHOA ras homolog family member A
RNASE3 ribonuclease, RNase A family, 3
ROBO4 roundabout, axon guidance receptor, homolog 4 (Drosophila)
ROCK2 Rho-associated, coiled-coil containing protein kinase 2
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1
RUNX1T1 runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
RXRA retinoid X receptor, alpha
RYR2 ryanodine receptor 2 (cardiac)
S100A10 S100 calcium binding protein A10
SAE1 SUMO1 activating enzyme subunit 1
SCN9A sodium channel, voltage gated, type IX alpha subunit
SERPINB4 serpin peptidase inhibitor, clade B (ovalbumin), member 4
SET SET nuclear proto-oncogene
SHH sonic hedgehog
SIN3B SIN3 transcription regulator family member B
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
SLC1A2 solute carrier family 1 (glial high affinity glutamate transporter), member 2
SLC23A2 solute carrier family 23 (ascorbic acid transporter), member 2
SLC2A2 solute carrier family 2 (facilitated glucose transporter), member 2
SLC4A1 solute carrier family 4 (anion exchanger), member 1 (Diego blood group)
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SLPI secretory leukocyte peptidase inhibitor
SMAD4 SMAD family member 4
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SNRNP70 small nuclear ribonucleoprotein 70kDa (U1)
SOD1 superoxide dismutase 1, soluble
SOST sclerostin
SP1 Sp1 transcription factor
SRSF1 serine/arginine-rich splicing factor 1
SRY sex determining region Y
ST14 suppression of tumorigenicity 14 (colon carcinoma)
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STIM1 stromal interaction molecule 1
STON2 stonin 2
SYT2 synaptotagmin II
TF transferrin
TFE3 transcription factor binding to IGHM enhancer 3
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TFRC transferrin receptor
TGFB1 transforming growth factor, beta 1
TGFBI transforming growth factor, beta-induced, 68kDa
TGM2 transglutaminase 2
THBS1 thrombospondin 1
TKFC triokinase/FMN cyclase
TLR2 toll-like receptor 2
TLR4 toll-like receptor 4
TMOD1 tropomodulin 1
TNFRSF10A tumor necrosis factor receptor superfamily, member 10a
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TNNT2 troponin T type 2 (cardiac)
TOB1 transducer of ERBB2, 1
TOMM40 translocase of outer mitochondrial membrane 40 homolog (yeast)
TP53 tumor protein p53
TP63 tumor protein p63
TPCN2 two pore segment channel 2
TPM1 tropomyosin 1 (alpha)
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TRIM25 tripartite motif containing 25
TRPC1 transient receptor potential cation channel, subfamily C, member 1
TRPC3 transient receptor potential cation channel, subfamily C, member 3
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TSC2 tuberous sclerosis 2
TSPO translocator protein (18kDa)
TTN titin
TXNIP thioredoxin interacting protein
UBA2 ubiquitin-like modifier activating enzyme 2
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)
UCP3 uncoupling protein 3 (mitochondrial, proton carrier)
UGT1A6 UDP glucuronosyltransferase 1 family, polypeptide A6
UMOD uromodulin
UNG uracil-DNA glycosylase
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VEGFA vascular endothelial growth factor A
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
VIM vimentin
VIP vasoactive intestinal peptide
VWF von Willebrand factor
WNT3A wingless-type MMTV integration site family, member 3A
YBX1 Y box binding protein 1
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa
ZMYM2 zinc finger, MYM-type 2
ZNF804A zinc finger protein 804A