integral component of endoplasmic reticulum membrane Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description The component of the endoplasmic reticulum membrane consisting of gene products and protein complexes that have some part that penetrates at least one leaflet of the membrane bilayer. This component includes gene products that are buried in the bilayer with no exposure outside the bilayer. (Gene Ontology, GO_0030176)
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86 proteins co-occuring with the integral component of endoplasmic reticulum membrane cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
HLA-B major histocompatibility complex, class I, B 1.89662
TAPBP TAP binding protein (tapasin) 1.87382
PIGT phosphatidylinositol glycan anchor biosynthesis, class T 1.45986
GPAA1 glycosylphosphatidylinositol anchor attachment 1 1.42655
INSIG1 insulin induced gene 1 1.31951
INSIG2 insulin induced gene 2 1.28196
CALR calreticulin 1.0741
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) 1.02032
HLA-A major histocompatibility complex, class I, A 0.992693
B2M beta-2-microglobulin 0.989759
HLA-E major histocompatibility complex, class I, E 0.937377
CANX calnexin 0.934072
ERLIN2 ER lipid raft associated 2 0.921386
AMFR autocrine motility factor receptor, E3 ubiquitin protein ligase 0.909716
TMUB1 transmembrane and ubiquitin-like domain containing 1 0.795145
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12 0.710136
SEC61A1 Sec61 alpha 1 subunit (S. cerevisiae) 0.708366
CLP1 cleavage and polyadenylation factor I subunit 1 0.703067
HLA-C major histocompatibility complex, class I, C 0.688139
PIGK phosphatidylinositol glycan anchor biosynthesis, class K 0.676368
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase 0.670292
ORM2 orosomucoid 2 0.656464
ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1 0.654741
TAPBPL TAP binding protein-like 0.640145
ICMT isoprenylcysteine carboxyl methyltransferase 0.592652
VCP valosin containing protein 0.588456
REEP5 receptor accessory protein 5 0.579251
TRAM1 translocation associated membrane protein 1 0.560943
SNRPA1 small nuclear ribonucleoprotein polypeptide A' 0.538649
RNF139 ring finger protein 139 0.503099
LCMT1 leucine carboxyl methyltransferase 1 0.501881
PIGL phosphatidylinositol glycan anchor biosynthesis, class L 0.495395
SCAP SREBF chaperone 0.468001
COL4A3BP collagen, type IV, alpha 3 (Goodpasture antigen) binding protein 0.465198
PDIA3 protein disulfide isomerase family A, member 3 0.456012
PBX2 pre-B-cell leukemia homeobox 2 0.446465
BCAP31 B-cell receptor-associated protein 31 0.445672
REXO1L1P REX1, RNA exonuclease 1 homolog (S. cerevisiae)-like 1, pseudogene 0.444482
KLRC1 killer cell lectin-like receptor subfamily C, member 1 0.429465
REEP1 receptor accessory protein 1 0.427497
SCD stearoyl-CoA desaturase (delta-9-desaturase) 0.41221
HYOU1 hypoxia up-regulated 1 0.400139
KLRD1 killer cell lectin-like receptor subfamily D, member 1 0.395098
WRB tryptophan rich basic protein 0.392001
OSBP oxysterol binding protein 0.375434
KLRC2 killer cell lectin-like receptor subfamily C, member 2 0.373132
SYVN1 synovial apoptosis inhibitor 1, synoviolin 0.365859
NHS Nance-Horan syndrome (congenital cataracts and dental anomalies) 0.357467
ABCB9 ATP-binding cassette, sub-family B (MDR/TAP), member 9 0.354042
CD48 CD48 molecule 0.349484
RCE1 Ras converting CAAX endopeptidase 1 0.333602
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1 0.332848
CD4 CD4 molecule 0.330966
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9 0.323075
PURB purine-rich element binding protein B 0.320077
ZFYVE1 zinc finger, FYVE domain containing 1 0.298826
HEPH hephaestin 0.297713
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein 0.286614
NXT1 nuclear transport factor 2-like export factor 1 0.279245
ORMDL2 ORMDL sphingolipid biosynthesis regulator 2 0.255107
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant 0.252564
NPAS4 neuronal PAS domain protein 4 0.240996
TBCE tubulin folding cofactor E 0.237042
PCTP phosphatidylcholine transfer protein 0.226686
FLAD1 flavin adenine dinucleotide synthetase 1 0.224558
DAD1 defender against cell death 1 0.22279
CKAP4 cytoskeleton-associated protein 4 0.22173
SEC23B Sec23 homolog B (S. cerevisiae) 0.221025
ORMDL1 ORMDL sphingolipid biosynthesis regulator 1 0.215412
TPP2 tripeptidyl peptidase II 0.210894
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3 0.197993
PCDH8 protocadherin 8 0.195353
CD52 CD52 molecule 0.189222
KCNT1 potassium channel, sodium activated subfamily T, member 1 0.188905
SEC63 SEC63 homolog (S. cerevisiae) 0.18859
HLA-DPB1 major histocompatibility complex, class II, DP beta 1 0.186397
CPSF3 cleavage and polyadenylation specific factor 3, 73kDa 0.178011
IRF1 interferon regulatory factor 1 0.174911
ATL1 atlastin GTPase 1 0.173003
H6PD hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) 0.17141
IRF2 interferon regulatory factor 2 0.164315
ASNA1 arsA arsenite transporter, ATP-binding, homolog 1 (bacterial) 0.164089
TSHB thyroid stimulating hormone, beta 0.161693
RPN1 ribophorin I 0.161693
SRPR signal recognition particle receptor (docking protein) 0.158315
TRAC T cell receptor alpha constant 0.156342