integral Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

200 genes co-occuring with the biological term integral in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ADAM12 ADAM metallopeptidase domain 12
ADCY8 adenylate cyclase 8 (brain)
ADIPOR1 adiponectin receptor 1
ADIPOR2 adiponectin receptor 2
ADRB2 adrenoceptor beta 2, surface
AFF1 AF4/FMR2 family, member 1
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3
AGTRAP angiotensin II receptor-associated protein
AHR aryl hydrocarbon receptor
AICDA activation-induced cytidine deaminase
APC adenomatous polyposis coli
APP amyloid beta (A4) precursor protein
ARF6 ADP-ribosylation factor 6
ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1
ASB11 ankyrin repeat and SOCS box containing 11, E3 ubiquitin protein ligase
ATL1 atlastin GTPase 1
ATM ATM serine/threonine kinase
AVP arginine vasopressin
BACE2 beta-site APP-cleaving enzyme 2
BCAP31 B-cell receptor-associated protein 31
BCL2 B-cell CLL/lymphoma 2
BGN biglycan
BMP15 bone morphogenetic protein 15
BMP7 bone morphogenetic protein 7
BSCL2 Berardinelli-Seip congenital lipodystrophy 2 (seipin)
C3AR1 complement component 3a receptor 1
CAV1 caveolin 1, caveolae protein, 22kDa
CAV2 caveolin 2
CD1D CD1d molecule
CD34 CD34 molecule
CD44 CD44 molecule (Indian blood group)
CD46 CD46 molecule, complement regulatory protein
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CLDN4 claudin 4
CLEC6A C-type lectin domain family 6, member A
CLIC1 chloride intracellular channel 1
CLIC4 chloride intracellular channel 4
CNGA1 cyclic nucleotide gated channel alpha 1
CREBBP CREB binding protein
CYBA cytochrome b-245, alpha polypeptide
CYBB cytochrome b-245, beta polypeptide
CYGB cytoglobin
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DEFA5 defensin, alpha 5, Paneth cell-specific
DEFB4A defensin, beta 4A
DGCR8 DGCR8 microprocessor complex subunit
DMD dystrophin
DYSF dysferlin
EDN1 endothelin 1
EEF1A1 eukaryotic translation elongation factor 1 alpha 1
EGFR epidermal growth factor receptor
ELP5 elongator acetyltransferase complex subunit 5
ELP6 elongator acetyltransferase complex subunit 6
EMD emerin
ENPEP glutamyl aminopeptidase (aminopeptidase A)
ERBB2 erb-b2 receptor tyrosine kinase 2
ERBB3 erb-b2 receptor tyrosine kinase 3
ESR1 estrogen receptor 1
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
FASLG Fas ligand (TNF superfamily, member 6)
FGF2 fibroblast growth factor 2 (basic)
FGFR3 fibroblast growth factor receptor 3
FST follistatin
GAPDH glyceraldehyde-3-phosphate dehydrogenase
GATA1 GATA binding protein 1 (globin transcription factor 1)
GATA3 GATA binding protein 3
GDF9 growth differentiation factor 9
GEMIN8 gem (nuclear organelle) associated protein 8
GREM1 gremlin 1, DAN family BMP antagonist
GSS glutathione synthetase
HACD2 3-hydroxyacyl-CoA dehydratase 2
HDAC1 histone deacetylase 1
HMGB1 high mobility group box 1
IL1B interleukin 1, beta
IL3RA interleukin 3 receptor, alpha (low affinity)
IL6 interleukin 6
INS insulin
IPMK inositol polyphosphate multikinase
IRAK4 interleukin-1 receptor-associated kinase 4
IRF3 interferon regulatory factor 3
IRF7 interferon regulatory factor 7
JAM3 junctional adhesion molecule 3
JDP2 Jun dimerization protein 2
KDM1A lysine (K)-specific demethylase 1A
KISS1 KiSS-1 metastasis-suppressor
KMT2C lysine (K)-specific methyltransferase 2C
KMT2D lysine (K)-specific methyltransferase 2D
KPNA2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1)
KPNB1 karyopherin (importin) beta 1
KRIT1 KRIT1, ankyrin repeat containing
LBR lamin B receptor
LMTK2 lemur tyrosine kinase 2
LNPEP leucyl/cystinyl aminopeptidase
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1
MAFK v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K
MAL mal, T-cell differentiation protein
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MAPK8 mitogen-activated protein kinase 8
MAVS mitochondrial antiviral signaling protein
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor)
MIR146A microRNA 146a
MME membrane metallo-endopeptidase
MMP1 matrix metallopeptidase 1
MMP26 matrix metallopeptidase 26
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYD88 myeloid differentiation primary response 88
NAMPT nicotinamide phosphoribosyltransferase
NELFA negative elongation factor complex member A
NELFB negative elongation factor complex member B
NELFCD negative elongation factor complex member C/D
NELFE negative elongation factor complex member E
NFE2L2 nuclear factor, erythroid 2-like 2
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NFX1 nuclear transcription factor, X-box binding 1
NLGN2 neuroligin 2
NOG noggin
NOX3 NADPH oxidase 3
NPLOC4 nuclear protein localization 4 homolog (S. cerevisiae)
NSMCE2 non-SMC element 2, MMS21 homolog (S. cerevisiae)
OGFR opioid growth factor receptor
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
P2RY1 purinergic receptor P2Y, G-protein coupled, 1
P2RY12 purinergic receptor P2Y, G-protein coupled, 12
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PALLD palladin, cytoskeletal associated protein
PAQR8 progestin and adipoQ receptor family member VIII
PARK7 parkinson protein 7
PDPK1 3-phosphoinositide dependent protein kinase 1
PEA15 phosphoprotein enriched in astrocytes 15
PER1 period circadian clock 1
PI4KB phosphatidylinositol 4-kinase, catalytic, beta
PITPNC1 phosphatidylinositol transfer protein, cytoplasmic 1
PKD2 polycystic kidney disease 2 (autosomal dominant)
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
PLSCR1 phospholipid scramblase 1
PMEL premelanosome protein
PNPT1 polyribonucleotide nucleotidyltransferase 1
PPAPDC2 phosphatidic acid phosphatase type 2 domain containing 2
PPARG peroxisome proliferator-activated receptor gamma
PPM1D protein phosphatase, Mg2+/Mn2+ dependent, 1D
PPP1R10 protein phosphatase 1, regulatory subunit 10
PROX1 prospero homeobox 1
PRSS36 protease, serine, 36
PSMG1 proteasome (prosome, macropain) assembly chaperone 1
PTEN phosphatase and tensin homolog
PTX3 pentraxin 3, long
RBFOX2 RNA binding protein, fox-1 homolog (C. elegans) 2
RECQL RecQ helicase-like
RECQL4 RecQ protein-like 4
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RHOA ras homolog family member A
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
ROMO1 reactive oxygen species modulator 1
SAMHD1 SAM domain and HD domain 1
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1
SCN5A sodium channel, voltage gated, type V alpha subunit
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
SFMBT1 Scm-like with four mbt domains 1
SFTPC surfactant protein C
SIVA1 SIVA1, apoptosis-inducing factor
SLC38A2 solute carrier family 38, member 2
SLC39A6 solute carrier family 39 (zinc transporter), member 6
SLIT1 slit homolog 1 (Drosophila)
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1
SMDT1 single-pass membrane protein with aspartate-rich tail 1
SMN1 survival of motor neuron 1, telomeric
SOD1 superoxide dismutase 1, soluble
SPG11 spastic paraplegia 11 (autosomal recessive)
SPHK1 sphingosine kinase 1
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STAT5B signal transducer and activator of transcription 5B
STIM1 stromal interaction molecule 1
SUPT16H suppressor of Ty 16 homolog (S. cerevisiae)
SUPV3L1 suppressor of var1, 3-like 1 (S. cerevisiae)
SYVN1 synovial apoptosis inhibitor 1, synoviolin
TAF1D TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa
TERT telomerase reverse transcriptase
TEX14 testis expressed 14
TGFB1 transforming growth factor, beta 1
TIMP4 TIMP metallopeptidase inhibitor 4
TOP2A topoisomerase (DNA) II alpha 170kDa
TOR1A torsin family 1, member A (torsin A)
TP53 tumor protein p53
TP63 tumor protein p63
TRPC1 transient receptor potential cation channel, subfamily C, member 1
TRPV4 transient receptor potential cation channel, subfamily V, member 4
UFD1L ubiquitin fusion degradation 1 like (yeast)
UXT ubiquitously-expressed, prefoldin-like chaperone
VCP valosin containing protein
VDAC1 voltage-dependent anion channel 1
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VEGFA vascular endothelial growth factor A
YBX1 Y box binding protein 1
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta
ZEB1 zinc finger E-box binding homeobox 1
ZKSCAN3 zinc finger with KRAB and SCAN domains 3