interface Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

443 genes co-occuring with the biological term interface in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1
ACD adrenocortical dysplasia homolog (mouse)
ACKR2 atypical chemokine receptor 2
ACTA1 actin, alpha 1, skeletal muscle
ACTR2 ARP2 actin-related protein 2 homolog (yeast)
ACTR3 ARP3 actin-related protein 3 homolog (yeast)
ACY1 aminoacylase 1
ADM2 adrenomedullin 2
ADORA2A adenosine A2a receptor
ADORA3 adenosine A3 receptor
ADRB1 adrenoceptor beta 1
ADRB2 adrenoceptor beta 2, surface
AGTR1 angiotensin II receptor, type 1
AGTR2 angiotensin II receptor, type 2
AHSP alpha hemoglobin stabilizing protein
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALB albumin
ALOX5 arachidonate 5-lipoxygenase
ALPL alkaline phosphatase, liver/bone/kidney
AMPH amphiphysin
ANKS1B ankyrin repeat and sterile alpha motif domain containing 1B
AOC1 amine oxidase, copper containing 1
APBB1 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
APOA1 apolipoprotein A-I
APOBEC3B apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B
APOBEC3C apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C
APOBEC3G apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G
APOC1 apolipoprotein C-I
APOE apolipoprotein E
APOH apolipoprotein H (beta-2-glycoprotein I)
APP amyloid beta (A4) precursor protein
AQP1 aquaporin 1 (Colton blood group)
AR androgen receptor
ARF1 ADP-ribosylation factor 1
ARF6 ADP-ribosylation factor 6
ARHGAP24 Rho GTPase activating protein 24
ARHGAP26 Rho GTPase activating protein 26
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12
ARHGEF7 Rho guanine nucleotide exchange factor (GEF) 7
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
ATG14 autophagy related 14
ATL1 atlastin GTPase 1
ATP6V0A2 ATPase, H+ transporting, lysosomal V0 subunit a2
ATP7B ATPase, Cu++ transporting, beta polypeptide
B2M beta-2-microglobulin
B4GALT1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
BAK1 BCL2-antagonist/killer 1
BAX BCL2-associated X protein
BCAP31 B-cell receptor-associated protein 31
BCL2L1 BCL2-like 1
BECN1 beclin 1, autophagy related
BID BH3 interacting domain death agonist
BIRC2 baculoviral IAP repeat containing 2
BIRC5 baculoviral IAP repeat containing 5
BPIFA1 BPI fold containing family A, member 1
BRAF B-Raf proto-oncogene, serine/threonine kinase
BRCA1 breast cancer 1, early onset
BRD2 bromodomain containing 2
BSG basigin (Ok blood group)
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B
BUB3 BUB3 mitotic checkpoint protein
C5AR1 complement component 5a receptor 1
C9 complement component 9
CALCRL calcitonin receptor-like
CAMP cathelicidin antimicrobial peptide
CARD11 caspase recruitment domain family, member 11
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP6 caspase 6, apoptosis-related cysteine peptidase
CASP8 caspase 8, apoptosis-related cysteine peptidase
CASP9 caspase 9, apoptosis-related cysteine peptidase
CCAR2 cell cycle and apoptosis regulator 2
CCDC88A coiled-coil domain containing 88A
CCL17 chemokine (C-C motif) ligand 17
CCL2 chemokine (C-C motif) ligand 2
CCNT1 cyclin T1
CCR2 chemokine (C-C motif) receptor 2
CD1D CD1d molecule
CD209 CD209 molecule
CD28 CD28 molecule
CD40LG CD40 ligand
CD46 CD46 molecule, complement regulatory protein
CD47 CD47 molecule
CD59 CD59 molecule, complement regulatory protein
CD69 CD69 molecule
CD81 CD81 molecule
CD82 CD82 molecule
CD86 CD86 molecule
CDC42SE2 CDC42 small effector 2
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDX2 caudal type homeobox 2
CENPF centromere protein F, 350/400kDa
CFH complement factor H
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CGA glycoprotein hormones, alpha polypeptide
CHRNA4 cholinergic receptor, nicotinic, alpha 4 (neuronal)
CHRNA7 cholinergic receptor, nicotinic, alpha 7 (neuronal)
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
CHRNE cholinergic receptor, nicotinic, epsilon (muscle)
CKM creatine kinase, muscle
CLCA1 chloride channel accessory 1
CLCN5 chloride channel, voltage-sensitive 5
CLCNKA chloride channel, voltage-sensitive Ka
CLDN5 claudin 5
CLINT1 clathrin interactor 1
CNOT1 CCR4-NOT transcription complex, subunit 1
CNOT8 CCR4-NOT transcription complex, subunit 8
CNR2 cannabinoid receptor 2 (macrophage)
COL4A1 collagen, type IV, alpha 1
CORIN corin, serine peptidase
CP ceruloplasmin (ferroxidase)
CPS1 carbamoyl-phosphate synthase 1, mitochondrial
CPSF6 cleavage and polyadenylation specific factor 6, 68kDa
CRYAB crystallin, alpha B
CRYGD crystallin, gamma D
CSF1 colony stimulating factor 1 (macrophage)
CSF2RA colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)
CSF3R colony stimulating factor 3 receptor (granulocyte)
CSH1 chorionic somatomammotropin hormone 1 (placental lactogen)
CSH2 chorionic somatomammotropin hormone 2
CSNK2A1 casein kinase 2, alpha 1 polypeptide
CSTB cystatin B (stefin B)
CTGF connective tissue growth factor
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTNND1 catenin (cadherin-associated protein), delta 1
CTNND2 catenin (cadherin-associated protein), delta 2
CUL5 cullin 5
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL8 chemokine (C-X-C motif) ligand 8
CXCL9 chemokine (C-X-C motif) ligand 9
CXCR1 chemokine (C-X-C motif) receptor 1
CXCR2 chemokine (C-X-C motif) receptor 2
CXCR3 chemokine (C-X-C motif) receptor 3
CXCR4 chemokine (C-X-C motif) receptor 4
CXCR6 chemokine (C-X-C motif) receptor 6
DDR1 discoidin domain receptor tyrosine kinase 1
DEFA5 defensin, alpha 5, Paneth cell-specific
DKK3 dickkopf WNT signaling pathway inhibitor 3
DLD dihydrolipoamide dehydrogenase
DMC1 DNA meiotic recombinase 1
DMD dystrophin
DNM1 dynamin 1
DPP4 dipeptidyl-peptidase 4
DRD2 dopamine receptor D2
DSG3 desmoglein 3
EDC3 enhancer of mRNA decapping 3
EGFR epidermal growth factor receptor
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2
ELK1 ELK1, member of ETS oncogene family
ENG endoglin
EP300 E1A binding protein p300
EPB41L3 erythrocyte membrane protein band 4.1-like 3
ERBB2 erb-b2 receptor tyrosine kinase 2
ERBB3 erb-b2 receptor tyrosine kinase 3
ERCC1 excision repair cross-complementation group 1
ERCC4 excision repair cross-complementation group 4
ERN2 endoplasmic reticulum to nucleus signaling 2
ESR1 estrogen receptor 1
ETF1 eukaryotic translation termination factor 1
EXOC2 exocyst complex component 2
EXOC8 exocyst complex component 8
F10 coagulation factor X
FANCM Fanconi anemia, complementation group M
FASN fatty acid synthase
FCAR Fc fragment of IgA receptor
FCGR3A Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
FCGRT Fc fragment of IgG, receptor, transporter, alpha
FCN1 ficolin (collagen/fibrinogen domain containing) 1
FGA fibrinogen alpha chain
FGF1 fibroblast growth factor 1 (acidic)
FGF10 fibroblast growth factor 10
FGF2 fibroblast growth factor 2 (basic)
FGF21 fibroblast growth factor 21
FGFR1 fibroblast growth factor receptor 1
FLG filaggrin
FN1 fibronectin 1
FOXO4 forkhead box O4
FOXP2 forkhead box P2
FURIN furin (paired basic amino acid cleaving enzyme)
G6PD glucose-6-phosphate dehydrogenase
GABRA1 gamma-aminobutyric acid (GABA) A receptor, alpha 1
GABRB3 gamma-aminobutyric acid (GABA) A receptor, beta 3
GADD45A growth arrest and DNA-damage-inducible, alpha
GARS glycyl-tRNA synthetase
GBF1 golgi brefeldin A resistant guanine nucleotide exchange factor 1
GDF15 growth differentiation factor 15
GFM1 G elongation factor, mitochondrial 1
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase)
GH2 growth hormone 2
GHR growth hormone receptor
GJA1 gap junction protein, alpha 1, 43kDa
GLRA1 glycine receptor, alpha 1
GLRB glycine receptor, beta
GLS glutaminase
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GNAS GNAS complex locus
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1
GNB2L1 guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1
GNLY granulysin
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)
GNRHR gonadotropin-releasing hormone receptor
GOLIM4 golgi integral membrane protein 4
GPC4 glypican 4
GRIK2 glutamate receptor, ionotropic, kainate 2
GRK6 G protein-coupled receptor kinase 6
GSTA1 glutathione S-transferase alpha 1
GSTP1 glutathione S-transferase pi 1
GSTT1 glutathione S-transferase theta 1
GTF2H5 general transcription factor IIH, polypeptide 5
GUCY2D guanylate cyclase 2D, membrane (retina-specific)
H1F0 H1 histone family, member 0
HBA1 hemoglobin, alpha 1
HBA2 hemoglobin, alpha 2
HBB hemoglobin, beta
HDAC3 histone deacetylase 3
HDAC4 histone deacetylase 4
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HIF1AN hypoxia inducible factor 1, alpha subunit inhibitor
HLA-G major histocompatibility complex, class I, G
HMOX2 heme oxygenase 2
HNF1A HNF1 homeobox A
HPN hepsin
HRAS Harvey rat sarcoma viral oncogene homolog
HRH1 histamine receptor H1
HRH2 histamine receptor H2
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1
HSF2 heat shock transcription factor 2
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1
HSPB6 heat shock protein, alpha-crystallin-related, B6
HTRA1 HtrA serine peptidase 1
HTT huntingtin
HVCN1 hydrogen voltage gated channel 1
IAPP islet amyloid polypeptide
ICAM1 intercellular adhesion molecule 1
IDO1 indoleamine 2,3-dioxygenase 1
IGF1 insulin-like growth factor 1 (somatomedin C)
IGF2 insulin-like growth factor 2
IGFBP1 insulin-like growth factor binding protein 1
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IGH immunoglobulin heavy locus
IGHA1 immunoglobulin heavy constant alpha 1
IL11 interleukin 11
IL12B interleukin 12B
IL17A interleukin 17A
IL24 interleukin 24
IL6 interleukin 6
IL7 interleukin 7
IL7R interleukin 7 receptor
IRF1 interferon regulatory factor 1
ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
ITGB7 integrin, beta 7
JAK2 Janus kinase 2
KCNB1 potassium channel, voltage gated Shab related subfamily B, member 1
KCND2 potassium channel, voltage gated Shal related subfamily D, member 2
KCNE1 potassium channel, voltage gated subfamily E regulatory beta subunit 1
KCNJ3 potassium channel, inwardly rectifying subfamily J, member 3
KCNMB1 potassium channel subfamily M regulatory beta subunit 1
KCNMB2 potassium channel subfamily M regulatory beta subunit 2
KCNQ1 potassium channel, voltage gated KQT-like subfamily Q, member 1
KIF5B kinesin family member 5B
KLK5 kallikrein-related peptidase 5
KLK7 kallikrein-related peptidase 7
KMO kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
KMT2A lysine (K)-specific methyltransferase 2A
KRAS Kirsten rat sarcoma viral oncogene homolog
LAMA2 laminin, alpha 2
LAT linker for activation of T cells
LCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
LDLR low density lipoprotein receptor
LGALS1 lectin, galactoside-binding, soluble, 1
LILRB1 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1
LIPG lipase, endothelial
LRP1 low density lipoprotein receptor-related protein 1
LVRN laeverin
LYVE1 lymphatic vessel endothelial hyaluronan receptor 1
MAD1L1 MAD1 mitotic arrest deficient-like 1 (yeast)
MALT1 MALT1 paracaspase
MAPK14 mitogen-activated protein kinase 14
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2
MAVS mitochondrial antiviral signaling protein
MDC1 mediator of DNA-damage checkpoint 1
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MDM4 MDM4, p53 regulator
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
ME3 malic enzyme 3, NADP(+)-dependent, mitochondrial
MED12 mediator complex subunit 12
MED19 mediator complex subunit 19
MED26 mediator complex subunit 26
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor)
MIF4GD MIF4G domain containing
MMP13 matrix metallopeptidase 13
MMP2 matrix metallopeptidase 2
MMP25 matrix metallopeptidase 25
MMP3 matrix metallopeptidase 3
MMP9 matrix metallopeptidase 9
MRC1 mannose receptor, C type 1
MRC2 mannose receptor, C type 2
MTMR4 myotubularin related protein 4
MYBPC3 myosin binding protein C, cardiac
NAMPT nicotinamide phosphoribosyltransferase
NCOR2 nuclear receptor corepressor 2
NDC80 NDC80 kinetochore complex component
NEDD8 neural precursor cell expressed, developmentally down-regulated 8
NHEJ1 nonhomologous end-joining factor 1
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin)
NPR1 natriuretic peptide receptor 1
NRP1 neuropilin 1
NSD1 nuclear receptor binding SET domain protein 1
NUDT21 nudix (nucleoside diphosphate linked moiety X)-type motif 21
NUP153 nucleoporin 153kDa
NUP50 nucleoporin 50kDa
OCLN occludin
ORAI1 ORAI calcium release-activated calcium modulator 1
OSBP oxysterol binding protein
OSBPL11 oxysterol binding protein-like 11
OSBPL9 oxysterol binding protein-like 9
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PCSK5 proprotein convertase subtilisin/kexin type 5
PDHX pyruvate dehydrogenase complex, component X
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PIK3R6 phosphoinositide-3-kinase, regulatory subunit 6
PIR pirin (iron-binding nuclear protein)
PKD2 polycystic kidney disease 2 (autosomal dominant)
PLAC1 placenta-specific 1
PLAU plasminogen activator, urokinase
PLEK pleckstrin
PLK1 polo-like kinase 1
PMM2 phosphomannomutase 2
POMC proopiomelanocortin
PPARG peroxisome proliferator-activated receptor gamma
PPIE peptidylprolyl isomerase E (cyclophilin E)
PPP2R1B protein phosphatase 2, regulatory subunit A, beta
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha
PRKCQ protein kinase C, theta
PROZ protein Z, vitamin K-dependent plasma glycoprotein
PSIP1 PC4 and SFRS1 interacting protein 1
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTPN1 protein tyrosine phosphatase, non-receptor type 1
PTX3 pentraxin 3, long
PVRL1 poliovirus receptor-related 1 (herpesvirus entry mediator C)
PVRL4 poliovirus receptor-related 4
RAB1B RAB1B, member RAS oncogene family
RAB7A RAB7A, member RAS oncogene family
RAMP1 receptor (G protein-coupled) activity modifying protein 1
RAMP2 receptor (G protein-coupled) activity modifying protein 2
RAMP3 receptor (G protein-coupled) activity modifying protein 3
RAN RAN, member RAS oncogene family
RASSF5 Ras association (RalGDS/AF-6) domain family member 5
RB1 retinoblastoma 1
RBBP5 retinoblastoma binding protein 5
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
REV1 REV1, polymerase (DNA directed)
RHOA ras homolog family member A
RNASE3 ribonuclease, RNase A family, 3
RPA2 replication protein A2, 32kDa
RUNX1 runt-related transcription factor 1
RUNX1T1 runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
RUNX2 runt-related transcription factor 2
S100B S100 calcium binding protein B
SCAMP2 secretory carrier membrane protein 2
SCN2A sodium channel, voltage gated, type II alpha subunit
SEC23IP SEC23 interacting protein
SELL selectin L
SELP selectin P (granule membrane protein 140kDa, antigen CD62)
SELPLG selectin P ligand
SENP6 SUMO1/sentrin specific peptidase 6
SERPINA10 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10
SETX senataxin
SF1 splicing factor 1
SF3B1 splicing factor 3b, subunit 1, 155kDa
SFTPC surfactant protein C
SGK1 serum/glucocorticoid regulated kinase 1
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
SLC26A4 solute carrier family 26 (anion exchanger), member 4
SLC31A1 solute carrier family 31 (copper transporter), member 1
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4
SLC5A5 solute carrier family 5 (sodium/iodide cotransporter), member 5
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3
SMARCAL1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SNRPE small nuclear ribonucleoprotein polypeptide E
SNX9 sorting nexin 9
SOD1 superoxide dismutase 1, soluble
SOD2 superoxide dismutase 2, mitochondrial
SPRY2 sprouty homolog 2 (Drosophila)
STAT1 signal transducer and activator of transcription 1, 91kDa
STATH statherin
STEAP3 STEAP family member 3, metalloreductase
STMN1 stathmin 1
SUMO2 small ubiquitin-like modifier 2
SYT1 synaptotagmin I
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
TERT telomerase reverse transcriptase
TGFB1 transforming growth factor, beta 1
TGM2 transglutaminase 2
TJP1 tight junction protein 1
TLR2 toll-like receptor 2
TLR4 toll-like receptor 4
TNFAIP6 tumor necrosis factor, alpha-induced protein 6
TNPO3 transportin 3
TP53 tumor protein p53
TPI1 triosephosphate isomerase 1
TPM1 tropomyosin 1 (alpha)
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TREX2 three prime repair exonuclease 2
TRIB1 tribbles pseudokinase 1
TSFM Ts translation elongation factor, mitochondrial
TSHR thyroid stimulating hormone receptor
TSLP thymic stromal lymphopoietin
TTR transthyretin
TYMS thymidylate synthetase
U2AF2 U2 small nuclear RNA auxiliary factor 2
UBE2C ubiquitin-conjugating enzyme E2C
UBE2I ubiquitin-conjugating enzyme E2I
UBE2N ubiquitin-conjugating enzyme E2N
UBE2V2 ubiquitin-conjugating enzyme E2 variant 2
UBL4A ubiquitin-like 4A
UVRAG UV radiation resistance associated
VAMP7 vesicle-associated membrane protein 7
VAV1 vav 1 guanine nucleotide exchange factor
VEGFA vascular endothelial growth factor A
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
VIP vasoactive intestinal peptide
VTN vitronectin
VWF von Willebrand factor
WAS Wiskott-Aldrich syndrome
WNT1 wingless-type MMTV integration site family, member 1
XPC xeroderma pigmentosum, complementation group C
XPO1 exportin 1
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa
ZBTB17 zinc finger and BTB domain containing 17
ZNF326 zinc finger protein 326