interleukin-1-mediated signaling pathway Gene Set

Dataset GO Biological Process Annotations 2025
Category structural or functional annotations
Type biological process
Description A series of molecular signals initiated by the binding of interleukin-1 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. (Gene Ontology, GO_0070498)
External Link http://amigo.geneontology.org/amigo/term/GO:0070498
Similar Terms
Downloads & Tools

Genes

21 genes participating in the interleukin-1-mediated signaling pathway biological process from the curated GO Biological Process Annotations 2025 dataset.

Symbol Name
EGR1 early growth response 1
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
IL1B interleukin 1, beta
IL1R1 interleukin 1 receptor, type I
IL1RAP interleukin 1 receptor accessory protein
IRAK1 interleukin-1 receptor-associated kinase 1
IRAK2 interleukin-1 receptor-associated kinase 2
IRAK3 interleukin-1 receptor-associated kinase 3
IRAK4 interleukin-1 receptor-associated kinase 4
MAP3K7 mitogen-activated protein kinase kinase kinase 7
MAPK3 mitogen-activated protein kinase 3
MYD88 myeloid differentiation primary response 88
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5
ST18 suppression of tumorigenicity 18, zinc finger
TNIP2 TNFAIP3 interacting protein 2
TOLLIP toll interacting protein
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase