interleukin-6-mediated signaling pathway Gene Set

Dataset	GO Biological Process Annotations 2025
Category	structural or functional annotations
Type	biological process
Description	A series of molecular signals initiated by the binding of interleukin-6 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. (Gene Ontology, GO_0070102)
External Link	http://amigo.geneontology.org/amigo/term/GO:0070102
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Genes

13 genes participating in the interleukin-6-mediated signaling pathway biological process from the curated GO Biological Process Annotations 2025 dataset.

Symbol	Name
CEBPA	CCAAT/enhancer binding protein (C/EBP), alpha
CTR9	CTR9, Paf1/RNA polymerase II complex component
FER	fer (fps/fes related) tyrosine kinase
IL6	interleukin 6
IL6R	interleukin 6 receptor
IL6ST	interleukin 6 signal transducer
JAK1	Janus kinase 1
JAK2	Janus kinase 2
SMAD4	SMAD family member 4
SPI1	Spi-1 proto-oncogene
SRC	SRC proto-oncogene, non-receptor tyrosine kinase
ST18	suppression of tumorigenicity 18, zinc finger
STAT3	signal transducer and activator of transcription 3 (acute-phase response factor)