intermediate filament cytoskeleton Gene Set

Dataset COMPARTMENTS Experimental Protein Localization Evidence Scores
Category proteomics
Type cellular component
Description Cytoskeletal structure made from intermediate filaments, typically organized in the cytosol as an extended system that stretches from the nuclear envelope to the plasma membrane. Some intermediate filaments run parallel to the cell surface, while others traverse the cytosol; together they form an internal framework that helps support the shape and resilience of the cell. (Gene Ontology, GO_0045111)
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Genes

183 proteins localized to the intermediate filament cytoskeleton cellular component in low- or high-throughput protein localization assays from the COMPARTMENTS Experimental Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
NES nestin 1.9544
KIAA1919 KIAA1919 1.02676
TMEM131 transmembrane protein 131 1.02676
FUT10 fucosyltransferase 10 (alpha (1,3) fucosyltransferase) 1.02676
SLC10A3 solute carrier family 10, member 3 1.02676
ZNF189 zinc finger protein 189 1.02676
VIM vimentin 1.02676
FAM118B family with sequence similarity 118, member B 1.02676
PTPRE protein tyrosine phosphatase, receptor type, E 1.02676
KRT24 keratin 24, type I 1.02676
NCSTN nicastrin 1.02676
KRT13 keratin 13, type I 1.02676
PGM2 phosphoglucomutase 2 1.02676
PLEC plectin 1.02676
BTD biotinidase 1.02676
MPP1 membrane protein, palmitoylated 1, 55kDa 1.02676
ANKMY2 ankyrin repeat and MYND domain containing 2 1.02676
CANT1 calcium activated nucleotidase 1 1.02676
ANAPC4 anaphase promoting complex subunit 4 1.02676
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain 1.02676
ADD1 adducin 1 (alpha) 1.02676
CLYBL citrate lyase beta like 1.02676
USP47 ubiquitin specific peptidase 47 1.02676
PNPLA1 patatin-like phospholipase domain containing 1 1.02676
RPAP3 RNA polymerase II associated protein 3 0.233497
KRT20 keratin 20, type I 0.233497
C14ORF39 chromosome 14 open reading frame 39 0.233497
ACVR1C activin A receptor, type IC 0.233497
DHX57 DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57 0.233497
TRIM46 tripartite motif containing 46 0.233497
CYB561D2 cytochrome b561 family, member D2 0.233497
SLC25A48 solute carrier family 25, member 48 0.233497
TMEM249 transmembrane protein 249 0.233497
PCDHB4 protocadherin beta 4 0.233497
SUSD6 sushi domain containing 6 0.233497
MBLAC2 metallo-beta-lactamase domain containing 2 0.233497
KRT23 keratin 23, type I 0.233497
DOLPP1 dolichyldiphosphatase 1 0.233497
ZNF557 zinc finger protein 557 0.233497
UBE2K ubiquitin-conjugating enzyme E2K 0.233497
TACC1 transforming, acidic coiled-coil containing protein 1 0.233497
PFDN5 prefoldin subunit 5 0.233497
FBLN1 fibulin 1 0.233497
FBXO7 F-box protein 7 0.233497
CCT8 chaperonin containing TCP1, subunit 8 (theta) 0.233497
NEU3 sialidase 3 (membrane sialidase) 0.233497
C6ORF52 chromosome 6 open reading frame 52 0.233497
C19ORF25 chromosome 19 open reading frame 25 0.233497
ALS2 amyotrophic lateral sclerosis 2 (juvenile) 0.233497
PKN2 protein kinase N2 0.233497
DSTYK dual serine/threonine and tyrosine protein kinase 0.233497
PROCA1 protein interacting with cyclin A1 0.233497
RWDD4 RWD domain containing 4 0.233497
N4BP2 NEDD4 binding protein 2 0.233497
BPGM 2,3-bisphosphoglycerate mutase 0.233497
TGDS TDP-glucose 4,6-dehydratase 0.233497
COPA coatomer protein complex, subunit alpha 0.233497
GTF2E1 general transcription factor IIE, polypeptide 1, alpha 56kDa 0.233497
SPAG7 sperm associated antigen 7 0.233497
RMND5A required for meiotic nuclear division 5 homolog A (S. cerevisiae) 0.233497
GTSF1 gametocyte specific factor 1 0.233497
CCDC125 coiled-coil domain containing 125 0.233497
CGNL1 cingulin-like 1 0.233497
CGREF1 cell growth regulator with EF-hand domain 1 0.233497
KIAA1551 KIAA1551 0.233497
KIFAP3 kinesin-associated protein 3 0.233497
BEND2 BEN domain containing 2 0.233497
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase 0.233497
SEC62 SEC62 homolog (S. cerevisiae) 0.233497
HTRA2 HtrA serine peptidase 2 0.233497
OTUD3 OTU deubiquitinase 3 0.233497
NUP35 nucleoporin 35kDa 0.233497
NEDD4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase 0.233497
MYO5B myosin VB 0.233497
ZNF573 zinc finger protein 573 0.233497
CCDC94 coiled-coil domain containing 94 0.233497
STXBP4 syntaxin binding protein 4 0.233497
PCLO piccolo presynaptic cytomatrix protein 0.233497
CETN3 centrin, EF-hand protein, 3 0.233497
ZC3H11A zinc finger CCCH-type containing 11A 0.233497
NYAP2 neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 2 0.233497
PKDCC protein kinase domain containing, cytoplasmic 0.233497
NELL2 NEL-like 2 (chicken) 0.233497
RNF219 ring finger protein 219 0.233497
CARD10 caspase recruitment domain family, member 10 0.233497
SERGEF secretion regulating guanine nucleotide exchange factor 0.233497
ZNF175 zinc finger protein 175 0.233497
ITFG1 integrin alpha FG-GAP repeat containing 1 0.233497
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 0.233497
COL1A1 collagen, type I, alpha 1 0.233497
AGA aspartylglucosaminidase 0.233497
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) 0.233497
WDR37 WD repeat domain 37 0.233497
RNASEH1 ribonuclease H1 0.233497
TM6SF1 transmembrane 6 superfamily member 1 0.233497
WDR89 WD repeat domain 89 0.233497
KIF2C kinesin family member 2C 0.233497
PCF11 PCF11 cleavage and polyadenylation factor subunit 0.233497
KIAA1549 KIAA1549 0.233497
SRRM3 serine/arginine repetitive matrix 3 0.233497
TARS2 threonyl-tRNA synthetase 2, mitochondrial (putative) 0.233497
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 0.233497
SPIRE2 spire-type actin nucleation factor 2 0.233497
SYNE2 spectrin repeat containing, nuclear envelope 2 0.233497
CNKSR1 connector enhancer of kinase suppressor of Ras 1 0.233497
PGS1 phosphatidylglycerophosphate synthase 1 0.233497
KRT2 keratin 2, type II 0.233497
KRT8 keratin 8, type II 0.233497
C21ORF2 chromosome 21 open reading frame 2 0.233497
ARL11 ADP-ribosylation factor-like 11 0.233497
RNMTL1 RNA methyltransferase like 1 0.233497
CLK3 CDC-like kinase 3 0.233497
CMTM6 CKLF-like MARVEL transmembrane domain containing 6 0.233497
MRPS23 mitochondrial ribosomal protein S23 0.233497
AXL AXL receptor tyrosine kinase 0.233497
CCDC59 coiled-coil domain containing 59 0.233497
CCDC58 coiled-coil domain containing 58 0.233497
ZNF786 zinc finger protein 786 0.233497
PCYT2 phosphate cytidylyltransferase 2, ethanolamine 0.233497
CHID1 chitinase domain containing 1 0.233497
USP10 ubiquitin specific peptidase 10 0.233497
IP6K2 inositol hexakisphosphate kinase 2 0.233497
FANCL Fanconi anemia, complementation group L 0.233497
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 0.233497
EXD2 exonuclease 3'-5' domain containing 2 0.233497
PSMB4 proteasome (prosome, macropain) subunit, beta type, 4 0.233497
PTPN18 protein tyrosine phosphatase, non-receptor type 18 (brain-derived) 0.233497
PHACTR4 phosphatase and actin regulator 4 0.233497
RBM23 RNA binding motif protein 23 0.233497
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) 0.233497
ZYG11B zyg-11 family member B, cell cycle regulator 0.233497
CD99L2 CD99 molecule-like 2 0.233497
ERCC5 excision repair cross-complementation group 5 0.233497
TRIM52 tripartite motif containing 52 0.233497
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase 0.233497
KIF3C kinesin family member 3C 0.233497
NFATC4 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 0.233497
SLC31A2 solute carrier family 31 (copper transporter), member 2 0.233497
TOM1L2 target of myb1-like 2 (chicken) 0.233497
CRTAP cartilage associated protein 0.233497
FAM118A family with sequence similarity 118, member A 0.233497
DHX34 DEAH (Asp-Glu-Ala-His) box polypeptide 34 0.233497
BSDC1 BSD domain containing 1 0.233497
FAM161B family with sequence similarity 161, member B 0.233497
MDN1 MDN1, midasin homolog (yeast) 0.233497
QTRTD1 queuine tRNA-ribosyltransferase domain containing 1 0.233497
OBFC1 oligonucleotide/oligosaccharide-binding fold containing 1 0.233497
STAG2 stromal antigen 2 0.233497
ZFC3H1 zinc finger, C3H1-type containing 0.233497
RBM33 RNA binding motif protein 33 0.233497
C12ORF49 chromosome 12 open reading frame 49 0.233497
C19ORF57 chromosome 19 open reading frame 57 0.233497
SLC44A2 solute carrier family 44 (choline transporter), member 2 0.233497
RAB3IP RAB3A interacting protein 0.233497
SBF2 SET binding factor 2 0.233497
TTC4 tetratricopeptide repeat domain 4 0.233497
CHD3 chromodomain helicase DNA binding protein 3 0.233497
EIF1AD eukaryotic translation initiation factor 1A domain containing 0.233497
ZFAND6 zinc finger, AN1-type domain 6 0.233497
DNAJA2 DnaJ (Hsp40) homolog, subfamily A, member 2 0.233497
ZNF619 zinc finger protein 619 0.233497
NSFL1C NSFL1 (p97) cofactor (p47) 0.233497
GTPBP10 GTP-binding protein 10 (putative) 0.233497
BCAS4 breast carcinoma amplified sequence 4 0.233497
LAMP2 lysosomal-associated membrane protein 2 0.233497
ERAL1 Era-like 12S mitochondrial rRNA chaperone 1 0.233497
IPO4 importin 4 0.233497
EXOSC4 exosome component 4 0.233497
EXOSC9 exosome component 9 0.233497
BAG2 BCL2-associated athanogene 2 0.233497
NDOR1 NADPH dependent diflavin oxidoreductase 1 0.233497
KIAA0825 KIAA0825 0.233497
PIK3R3 phosphoinositide-3-kinase, regulatory subunit 3 (gamma) 0.233497
MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase 0.233497
CDCP1 CUB domain containing protein 1 0.233497
C17ORF70 chromosome 17 open reading frame 70 0.233497
UAP1L1 UDP-N-acetylglucosamine pyrophosphorylase 1 like 1 0.233497
USPL1 ubiquitin specific peptidase like 1 0.233497
PGM3 phosphoglucomutase 3 0.233497
ADAM22 ADAM metallopeptidase domain 22 0.233497
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9 0.233497
SMG7 SMG7 nonsense mediated mRNA decay factor 0.233497
ZFP69 ZFP69 zinc finger protein 0.233497