intermediate filament Gene Set

Dataset GO Cellular Component Annotations 2023
Category structural or functional annotations
Type biological process
Description A cytoskeletal structure that forms a distinct elongated structure, characteristically 10 nm in diameter, that occurs in the cytoplasm of eukaryotic cells. Intermediate filaments form a fibrous system, composed of chemically heterogeneous subunits and involved in mechanically integrating the various components of the cytoplasmic space. Intermediate filaments may be divided into five chemically distinct classes: Type I, acidic keratins; Type II, basic keratins; Type III, including desmin, vimentin and others; Type IV, neurofilaments and related filaments; and Type V, lamins. (Gene Ontology, GO_0005882)
External Link http://amigo.geneontology.org/amigo/term/GO:0005882
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Genes

70 proteins localized to the intermediate filament cellular component from the curated GO Cellular Component Annotations 2023 dataset.

Symbol Name
BFSP1 beaded filament structural protein 1, filensin
BFSP2 beaded filament structural protein 2, phakinin
C9ORF16 chromosome 9 open reading frame 16
CLIP1 CAP-GLY domain containing linker protein 1
CSNK1A1 casein kinase 1, alpha 1
DSP desmoplakin
DST dystonin
EPPK1 epiplakin 1
EVPL envoplakin
FBF1 Fas (TNFRSF6) binding factor 1
GFAP glial fibrillary acidic protein
GPER1 G protein-coupled estrogen receptor 1
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
INA internexin neuronal intermediate filament protein, alpha
KRT1 keratin 1, type II
KRT10 keratin 10, type I
KRT13 keratin 13, type I
KRT14 keratin 14, type I
KRT16 keratin 16, type I
KRT17 keratin 17, type I
KRT18 keratin 18, type I
KRT2 keratin 2, type II
KRT20 keratin 20, type I
KRT25 keratin 25, type I
KRT3 keratin 3, type II
KRT36 keratin 36, type I
KRT4 keratin 4, type II
KRT5 keratin 5, type II
KRT6A keratin 6A, type II
KRT6B keratin 6B, type II
KRT7 keratin 7, type II
KRT71 keratin 71, type II
KRT72 keratin 72, type II
KRT73 keratin 73, type II
KRT74 keratin 74, type II
KRT75 keratin 75, type II
KRT76 keratin 76, type II
KRT77 keratin 77, type II
KRT78 keratin 78, type II
KRT79 keratin 79, type II
KRT8 keratin 8, type II
KRT80 keratin 80, type II
KRT81 keratin 81, type II
KRT82 keratin 82, type II
KRT83 keratin 83, type II
KRT84 keratin 84, type II
KRT85 keratin 85, type II
KRT86 keratin 86, type II
KRT9 keratin 9, type I
MACF1 microtubule-actin crosslinking factor 1
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1
NCKIPSD NCK interacting protein with SH3 domain
NEFL neurofilament, light polypeptide
NEFM neurofilament, medium polypeptide
NES nestin
PKP1 plakophilin 1
PKP2 plakophilin 2
PLEC plectin
PNN pinin, desmosome associated protein
PPL periplakin
PRPH peripherin
RTN2 reticulon 2
SACK1H scaffolding CK1 anchoring protein H
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SYNM synemin, intermediate filament protein
TCHP trichoplein, keratin filament binding
TLK2 tousled-like kinase 2
UPP2 uridine phosphorylase 2
VIM vimentin
VMAC vimentin-type intermediate filament associated coiled-coil protein