internal Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

261 genes co-occuring with the biological term internal in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ABCD1 ATP-binding cassette, sub-family D (ALD), member 1
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5
ADCY7 adenylate cyclase 7
AGO2 argonaute RISC catalytic component 2
AGTR1 angiotensin II receptor, type 1
AGTR2 angiotensin II receptor, type 2
AICDA activation-induced cytidine deaminase
ALB albumin
AMBP alpha-1-microglobulin/bikunin precursor
ANAPC5 anaphase promoting complex subunit 5
AP3D1 adaptor-related protein complex 3, delta 1 subunit
APC adenomatous polyposis coli
APOB apolipoprotein B
APOBEC3F apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3F
APOBEC3G apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G
APP amyloid beta (A4) precursor protein
AQP2 aquaporin 2 (collecting duct)
AQP4 aquaporin 4
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12
ATM ATM serine/threonine kinase
ATP5A1 ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle
B2M beta-2-microglobulin
BAG1 BCL2-associated athanogene
BCL2 B-cell CLL/lymphoma 2
BCL2L11 BCL2-like 11 (apoptosis facilitator)
BMP4 bone morphogenetic protein 4
BMPR1B bone morphogenetic protein receptor, type IB
BTN3A1 butyrophilin, subfamily 3, member A1
BYSL bystin-like
C3 complement component 3
C5 complement component 5
CA9 carbonic anhydrase IX
CACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
CAPN3 calpain 3, (p94)
CASR calcium-sensing receptor
CAT catalase
CCDC78 coiled-coil domain containing 78
CD9 CD9 molecule
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDH23 cadherin-related 23
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CELF1 CUGBP, Elav-like family member 1
CFHR4 complement factor H-related 4
CFHR5 complement factor H-related 5
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CHRM3 cholinergic receptor, muscarinic 3
CHRM5 cholinergic receptor, muscarinic 5
CLINT1 clathrin interactor 1
CNBP CCHC-type zinc finger, nucleic acid binding protein
CREBBP CREB binding protein
CSDE1 cold shock domain containing E1, RNA-binding
CSF2 colony stimulating factor 2 (granulocyte-macrophage)
CSK c-src tyrosine kinase
CX3CR1 chemokine (C-X3-C motif) receptor 1
CYGB cytoglobin
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
DDX5 DEAD (Asp-Glu-Ala-Asp) box helicase 5
DENND5A DENN/MADD domain containing 5A
DICER1 dicer 1, ribonuclease type III
DKC1 dyskeratosis congenita 1, dyskerin
DMD dystrophin
DROSHA drosha, ribonuclease type III
DYSF dysferlin
EDNRA endothelin receptor type A
EDNRB endothelin receptor type B
EGFR epidermal growth factor receptor
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2
EIF2S1 eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
EIF3A eukaryotic translation initiation factor 3, subunit A
EIF3C eukaryotic translation initiation factor 3, subunit C
EIF4G2 eukaryotic translation initiation factor 4 gamma, 2
EIF5B eukaryotic translation initiation factor 5B
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
ERAP1 endoplasmic reticulum aminopeptidase 1
ERBB2 erb-b2 receptor tyrosine kinase 2
ERBB4 erb-b2 receptor tyrosine kinase 4
ESR1 estrogen receptor 1
ESR2 estrogen receptor 2 (ER beta)
ESRRB estrogen-related receptor beta
FFAR1 free fatty acid receptor 1
FFAR3 free fatty acid receptor 3
FGF1 fibroblast growth factor 1 (acidic)
FGF2 fibroblast growth factor 2 (basic)
FLT1 fms-related tyrosine kinase 1
FLT3 fms-related tyrosine kinase 3
FTH1 ferritin, heavy polypeptide 1
GAP43 growth associated protein 43
GAPDH glyceraldehyde-3-phosphate dehydrogenase
GATA1 GATA binding protein 1 (globin transcription factor 1)
GGCX gamma-glutamyl carboxylase
GJA1 gap junction protein, alpha 1, 43kDa
GJB2 gap junction protein, beta 2, 26kDa
GLI3 GLI family zinc finger 3
GNB2L1 guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1
GSDMB gasdermin B
GUCY1B2 guanylate cyclase 1, soluble, beta 2 (pseudogene)
HBE1 hemoglobin, epsilon 1
HGS hepatocyte growth factor-regulated tyrosine kinase substrate
HIST1H1A histone cluster 1, H1a
HIST1H1B histone cluster 1, H1b
HIST1H1C histone cluster 1, H1c
HIST1H1D histone cluster 1, H1d
HLA-B major histocompatibility complex, class I, B
HMOX1 heme oxygenase 1
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1
HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2)
HNRNPD heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)
HNRNPDL heterogeneous nuclear ribonucleoprotein D-like
HNRNPL heterogeneous nuclear ribonucleoprotein L
HOXA1 homeobox A1
HOXA10 homeobox A10
HOXD9 homeobox D9
HPRT1 hypoxanthine phosphoribosyltransferase 1
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSPA1A heat shock 70kDa protein 1A
HSPB1 heat shock 27kDa protein 1
HTR1B 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
ICAM1 intercellular adhesion molecule 1
IFIH1 interferon induced with helicase C domain 1
IFITM3 interferon induced transmembrane protein 3
IFNB1 interferon, beta 1, fibroblast
IGF1R insulin-like growth factor 1 receptor
IGF2 insulin-like growth factor 2
IGH immunoglobulin heavy locus
IL24 interleukin 24
IL2RA interleukin 2 receptor, alpha
IL3 interleukin 3
IL6 interleukin 6
ILF2 interleukin enhancer binding factor 2
INSR insulin receptor
IRF2 interferon regulatory factor 2
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
JUN jun proto-oncogene
KDR kinase insert domain receptor
KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1
KRAS Kirsten rat sarcoma viral oncogene homolog
LCN1 lipocalin 1
LDB3 LIM domain binding 3
LEF1 lymphoid enhancer-binding factor 1
LGALS1 lectin, galactoside-binding, soluble, 1
LHX3 LIM homeobox 3
LUZP6 leucine zipper protein 6
LYN LYN proto-oncogene, Src family tyrosine kinase
MAPK3 mitogen-activated protein kinase 3
MAPK6 mitogen-activated protein kinase 6
MASP1 mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MCL1 myeloid cell leukemia 1
MCOLN1 mucolipin 1
MDC1 mediator of DNA-damage checkpoint 1
MED25 mediator complex subunit 25
MIR122 microRNA 122
MIR155 microRNA 155
MIR221 microRNA 221
MIR222 microRNA 222
MIR223 microRNA 223
MKNK1 MAP kinase interacting serine/threonine kinase 1
MMP12 matrix metallopeptidase 12
MMP2 matrix metallopeptidase 2
MMP3 matrix metallopeptidase 3
MMP9 matrix metallopeptidase 9
MPP5 membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5)
MRC2 mannose receptor, C type 2
MTCH1 mitochondrial carrier 1
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MTPN myotrophin
MTR 5-methyltetrahydrofolate-homocysteine methyltransferase
MUC1 mucin 1, cell surface associated
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYH9 myosin, heavy chain 9, non-muscle
NANOG Nanog homeobox
NDC80 NDC80 kinetochore complex component
NF1 neurofibromin 1
NFE2L2 nuclear factor, erythroid 2-like 2
NKRF NFKB repressing factor
NOS3 nitric oxide synthase 3 (endothelial cell)
NOTCH1 notch 1
NOX4 NADPH oxidase 4
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin)
ODC1 ornithine decarboxylase 1
ORAI1 ORAI calcium release-activated calcium modulator 1
OXTR oxytocin receptor
PABPC1 poly(A) binding protein, cytoplasmic 1
PARD6A par-6 family cell polarity regulator alpha
PARK2 parkin RBR E3 ubiquitin protein ligase
PARP1 poly (ADP-ribose) polymerase 1
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor)
PDPN podoplanin
PIM1 Pim-1 proto-oncogene, serine/threonine kinase
PINK1 PTEN induced putative kinase 1
PLAU plasminogen activator, urokinase
PLAUR plasminogen activator, urokinase receptor
PLD1 phospholipase D1, phosphatidylcholine-specific
PLG plasminogen
PMP2 peripheral myelin protein 2
POLL polymerase (DNA directed), lambda
POR P450 (cytochrome) oxidoreductase
POU5F1 POU class 5 homeobox 1
PREP prolyl endopeptidase
PRKCA protein kinase C, alpha
PRKCE protein kinase C, epsilon
PSAP prosaposin
PTK2B protein tyrosine kinase 2 beta
PTPN1 protein tyrosine phosphatase, non-receptor type 1
QSOX1 quiescin Q6 sulfhydryl oxidase 1
RHD Rh blood group, D antigen
RHOA ras homolog family member A
RNF146 ring finger protein 146
ROCK2 Rho-associated, coiled-coil containing protein kinase 2
RPA2 replication protein A2, 32kDa
RPAIN RPA interacting protein
RUNX1 runt-related transcription factor 1
RYR1 ryanodine receptor 1 (skeletal)
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SGCE sarcoglycan, epsilon
SHMT1 serine hydroxymethyltransferase 1 (soluble)
SLC6A1 solute carrier family 6 (neurotransmitter transporter), member 1
SNAI1 snail family zinc finger 1
SNRPA small nuclear ribonucleoprotein polypeptide A
SREBF1 sterol regulatory element binding transcription factor 1
SRPK1 SRSF protein kinase 1
SRSF3 serine/arginine-rich splicing factor 3
SSB Sjogren syndrome antigen B (autoantigen La)
STAT5A signal transducer and activator of transcription 5A
STIM1 stromal interaction molecule 1
TAX1BP3 Tax1 (human T-cell leukemia virus type I) binding protein 3
TEK TEK tyrosine kinase, endothelial
TFDP2 transcription factor Dp-2 (E2F dimerization partner 2)
TGFB1 transforming growth factor, beta 1
TGFBR1 transforming growth factor, beta receptor 1
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TIMP1 TIMP metallopeptidase inhibitor 1
TLR4 toll-like receptor 4
TOMM70A translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae)
TP53 tumor protein p53
TP63 tumor protein p63
TP73 tumor protein p73
TPH2 tryptophan hydroxylase 2
TRAF1 TNF receptor-associated factor 1
TRPC1 transient receptor potential cation channel, subfamily C, member 1
TRPM2 transient receptor potential cation channel, subfamily M, member 2
TRPM7 transient receptor potential cation channel, subfamily M, member 7
TSG101 tumor susceptibility 101
USH1C Usher syndrome 1C (autosomal recessive, severe)
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VEGFA vascular endothelial growth factor A
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
WWC1 WW and C2 domain containing 1
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa
ZEB1 zinc finger E-box binding homeobox 1