intrahepatic cholangiocarcinoma Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores
Category disease or phenotype associations
Type disease
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Genes

205 genes co-occuring with the disease intrahepatic cholangiocarcinoma in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
MUC2 mucin 2, oligomeric mucus/gel-forming 1.39477
KRT7 keratin 7, type II 1.3542
MUC5B mucin 5B, oligomeric mucus/gel-forming 1.34897
MUC1 mucin 1, cell surface associated 1.29877
PTPRE protein tyrosine phosphatase, receptor type, E 1.20137
KRT20 keratin 20, type I 1.16606
MBD2 methyl-CpG binding domain protein 2 1.08621
BICC1 BicC family RNA binding protein 1 1.06984
KRT19 keratin 19, type I 1.0606
AFP alpha-fetoprotein 1.03956
TP53 tumor protein p53 1.02735
KIAA1598 1.02355
TMC5 transmembrane channel-like 5 1.0109
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 0.95996
KRAS Kirsten rat sarcoma viral oncogene homolog 0.954108
CDX2 caudal type homeobox 2 0.949519
GOPC golgi-associated PDZ and coiled-coil motif containing 0.922149
S100P S100 calcium binding protein P 0.90732
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog 0.879424
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble 0.848716
GPC3 glypican 3 0.846669
HRAS Harvey rat sarcoma viral oncogene homolog 0.844211
MUC6 mucin 6, oligomeric mucus/gel-forming 0.838066
NAE1 NEDD8 activating enzyme E1 subunit 1 0.789672
FAR2 fatty acyl CoA reductase 2 0.787213
ROS1 ROS proto-oncogene 1 , receptor tyrosine kinase 0.779841
VEGFC vascular endothelial growth factor C 0.770027
RASGEF1A RasGEF domain family, member 1A 0.769618
SMYD3 SET and MYND domain containing 3 0.749644
RABGAP1L RAB GTPase activating protein 1-like 0.739488
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial 0.699517
UBE2M ubiquitin-conjugating enzyme E2M 0.679898
CDH17 cadherin 17, LI cadherin (liver-intestine) 0.678302
MUC4 mucin 4, cell surface associated 0.65763
TMEM11 transmembrane protein 11 0.651694
CXXC1 CXXC finger protein 1 0.650508
TACC3 transforming, acidic coiled-coil containing protein 3 0.650508
CCND1 cyclin D1 0.643404
ERRFI1 ERBB receptor feedback inhibitor 1 0.643009
SHC3 SHC (Src homology 2 domain containing) transforming protein 3 0.641827
IL12A interleukin 12A 0.631991
ALPPL2 alkaline phosphatase, placental-like 2 0.630027
ALPP alkaline phosphatase, placental 0.629635
ALPL alkaline phosphatase, liver/bone/kidney 0.629242
PER1 period circadian clock 1 0.628457
UBA3 ubiquitin-like modifier activating enzyme 3 0.621792
SLC7A6 solute carrier family 7 (amino acid transporter light chain, y+L system), member 6 0.620617
RAD51AP1 RAD51 associated protein 1 0.610838
AHCYL1 adenosylhomocysteinase-like 1 0.594843
PGRMC1 progesterone receptor membrane component 1 0.591337
ITIH1 inter-alpha-trypsin inhibitor heavy chain 1 0.585497
FHL1 four and a half LIM domains 1 0.571107
TFF1 trefoil factor 1 0.563723
CHST4 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4 0.556732
CKAP4 cytoskeleton-associated protein 4 0.551686
SLC38A1 solute carrier family 38, member 1 0.545481
CDH2 cadherin 2, type 1, N-cadherin (neuronal) 0.543155
AQP1 aquaporin 1 (Colton blood group) 0.538506
AGR3 anterior gradient 3 0.526904
ASXL1 additional sex combs like transcriptional regulator 1 0.526518
MMP7 matrix metallopeptidase 7 0.521888
TEP1 telomerase-associated protein 1 0.512648
EGFR epidermal growth factor receptor 0.511112
MET MET proto-oncogene, receptor tyrosine kinase 0.505739
ERBB2 erb-b2 receptor tyrosine kinase 2 0.503058
ASPH aspartate beta-hydroxylase 0.502675
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase 0.497703
PER3 period circadian clock 3 0.496939
NOTCH1 notch 1 0.493122
VSIG4 V-set and immunoglobulin domain containing 4 0.489311
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 0.487407
GGT2 gamma-glutamyltransferase 2 0.483224
SAV1 salvador family WW domain containing protein 1 0.479427
ABCC11 ATP-binding cassette, sub-family C (CFTR/MRP), member 11 0.478289
L1CAM L1 cell adhesion molecule 0.478289
PER2 period circadian clock 2 0.47753
ALB albumin 0.474119
PROM1 prominin 1 0.470332
SFN stratifin 0.462016
USP14 ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase) 0.458241
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 0.446935
MUC13 mucin 13, cell surface associated 0.43941
GPRC5A G protein-coupled receptor, class C, group 5, member A 0.431519
CEACAM8 carcinoembryonic antigen-related cell adhesion molecule 8 0.429266
EPCAM epithelial cell adhesion molecule 0.428516
MMP9 matrix metallopeptidase 9 0.425514
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 0.416147
TNC tenascin C 0.410909
BTC betacellulin 0.410909
PDLIM7 PDZ and LIM domain 7 (enigma) 0.408666
CD34 CD34 molecule 0.404184
SMAD4 SMAD family member 4 0.403438
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1 0.399334
GOT1 glutamic-oxaloacetic transaminase 1, soluble 0.397843
MLH1 mutL homolog 1 0.392257
TCEB2 transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B) 0.383337
F2 coagulation factor II (thrombin) 0.381852
SPP1 secreted phosphoprotein 1 0.379626
CLEC3A C-type lectin domain family 3, member A 0.377031
FXYD3 FXYD domain containing ion transport regulator 3 0.373328
CLEC2B C-type lectin domain family 2, member B 0.372217
FBN2 fibrillin 2 0.370368
HMGA1 high mobility group AT-hook 1 0.370368
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial 0.369628
FGFR2 fibroblast growth factor receptor 2 0.363347
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) 0.363347
GGT1 gamma-glutamyltransferase 1 0.363347
UGT2B11 UDP glucuronosyltransferase 2 family, polypeptide B11 0.358183
SLC43A2 solute carrier family 43 (amino acid system L transporter), member 2 0.350452
CLEC10A C-type lectin domain family 10, member A 0.349349
KRT8 keratin 8, type II 0.348246
MAGEA3 melanoma antigen family A3 0.345675
CLDN18 claudin 18 0.342006
BMX BMX non-receptor tyrosine kinase 0.340906
RPS6KB2 ribosomal protein S6 kinase, 70kDa, polypeptide 2 0.337608
CLDN4 claudin 4 0.335046
DPYD dihydropyrimidine dehydrogenase 0.333949
MIB1 mindbomb E3 ubiquitin protein ligase 1 0.331756
GPR17 G protein-coupled receptor 17 0.32993
NCAM1 neural cell adhesion molecule 1 0.328105
ZNF135 zinc finger protein 135 0.32701
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit 0.323002
CXCL5 chemokine (C-X-C motif) ligand 5 0.32009
RASSF1 Ras association (RalGDS/AF-6) domain family member 1 0.318635
UGT2B4 UDP glucuronosyltransferase 2 family, polypeptide B4 0.317909
GNAS GNAS complex locus 0.316456
FABP5 fatty acid binding protein 5 (psoriasis-associated) 0.304864
RERE arginine-glutamic acid dipeptide (RE) repeats 0.303059
CA10 carbonic anhydrase X 0.301615
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 0.300173
HOMER1 homer scaffolding protein 1 0.298011
ANKK1 ankyrin repeat and kinase domain containing 1 0.291539
BIRC5 baculoviral IAP repeat containing 5 0.286519
PCNA proliferating cell nuclear antigen 0.281868
WNT3 wingless-type MMTV integration site family, member 3 0.281153
RGMB repulsive guidance molecule family member b 0.279367
PTEN phosphatase and tensin homolog 0.278654
HDGF hepatoma-derived growth factor 0.273308
DCT dopachrome tautomerase 0.273308
LYVE1 lymphatic vessel endothelial hyaluronan receptor 1 0.272953
ABCB11 ATP-binding cassette, sub-family B (MDR/TAP), member 11 0.271174
OGG1 8-oxoguanine DNA glycosylase 0.268332
LGALS3 lectin, galactoside-binding, soluble, 3 0.261245
FSCN1 fascin actin-bundling protein 1 0.255946
BGN biglycan 0.255241
CD44 CD44 molecule (Indian blood group) 0.252422
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.25207
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 0.248203
CAPNS1 calpain, small subunit 1 0.248203
MIR214 microRNA 214 0.247852
CDKN2A cyclin-dependent kinase inhibitor 2A 0.24715
ANXA1 annexin A1 0.244345
MTSS1 metastasis suppressor 1 0.243295
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 0.241546
MSH2 mutS homolog 2 0.240497
PCYT1A phosphate cytidylyltransferase 1, choline, alpha 0.240497
NEUROG1 neurogenin 1 0.231448
ABCB4 ATP-binding cassette, sub-family B (MDR/TAP), member 4 0.229716
LHB luteinizing hormone beta polypeptide 0.224196
MIR22 microRNA 22 0.222479
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha 0.210253
CHFR checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase 0.205254
SHC2 SHC (Src homology 2 domain containing) transforming protein 2 0.205254
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 0.204593
BMI1 BMI1 proto-oncogene, polycomb ring finger 0.203933
FASLG Fas ligand (TNF superfamily, member 6) 0.203275
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 0.203275
ANXA2 annexin A2 0.199681
RNGTT RNA guanylyltransferase and 5'-phosphatase 0.198064
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila) 0.197099
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5 0.192031
HIST2H3PS2 histone cluster 2, H3, pseudogene 2 0.190786
EHF ets homologous factor 0.188632
YAP1 Yes-associated protein 1 0.187415
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 0.187113
H3F3A H3 histone, family 3A 0.185612
H3F3B H3 histone, family 3B (H3.3B) 0.185612
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 0.185016
FAXDC2 fatty acid hydroxylase domain containing 2 0.184424
MUC16 mucin 16, cell surface associated 0.182086
PTK7 protein tyrosine kinase 7 (inactive) 0.177576
LAMC2 laminin, gamma 2 0.168854
CLDN11 claudin 11 0.165874
EBAG9 estrogen receptor binding site associated, antigen, 9 0.165001
WNT2 wingless-type MMTV integration site family member 2 0.164786
HOXA1 homeobox A1 0.160387
CD151 CD151 molecule (Raph blood group) 0.160387
LGALS1 lectin, galactoside-binding, soluble, 1 0.158778
DEFB1 defensin, beta 1 0.158605
MMP2 matrix metallopeptidase 2 0.158434
RECK reversion-inducing-cysteine-rich protein with kazal motifs 0.157765
CHRM3 cholinergic receptor, muscarinic 3 0.139974
TCF4 transcription factor 4 0.139915
RCC1 regulator of chromosome condensation 1 0.139787
MARS methionyl-tRNA synthetase 0.139569
NCOA1 nuclear receptor coactivator 1 0.139342
COX5A cytochrome c oxidase subunit Va 0.134823
TPH1 tryptophan hydroxylase 1 0.13387
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) 0.133425
TYRO3 TYRO3 protein tyrosine kinase 0.131608
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip) 0.131497
NGF nerve growth factor (beta polypeptide) 0.130229
IVL involucrin 0.128224
DNMT1 DNA (cytosine-5-)-methyltransferase 1 0.126829
CXCR4 chemokine (C-X-C motif) receptor 4 0.126531