inward rectifier potassium channel activity Gene Set

Dataset GO Molecular Function Annotations
Category structural or functional annotations
Type molecular function
Description Catalysis of the transmembrane transfer of a potassium ion by an inwardly-rectifying voltage-gated channel. An inwardly rectifying current-voltage relation is one where at any given driving force the inward flow of K+ ions exceeds the outward flow for the opposite driving force. The inward-rectification is due to a voltage-dependent block of the channel pore by a specific ligand or ligands, and as a result the macroscopic conductance depends on the difference between membrane voltage and the K+ equilibrium potential rather than on membrane voltage itself. (Gene Ontology, GO_0005242)
External Link http://amigo.geneontology.org/amigo/term/GO:0005242
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Genes

21 genes performing the inward rectifier potassium channel activity molecular function from the curated GO Molecular Function Annotations dataset.

Symbol Name
KCNE2 potassium channel, voltage gated subfamily E regulatory beta subunit 2
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KCNH7 potassium channel, voltage gated eag related subfamily H, member 7
KCNJ1 potassium channel, inwardly rectifying subfamily J, member 1
KCNJ10 potassium channel, inwardly rectifying subfamily J, member 10
KCNJ11 potassium channel, inwardly rectifying subfamily J, member 11
KCNJ12 potassium channel, inwardly rectifying subfamily J, member 12
KCNJ13 potassium channel, inwardly rectifying subfamily J, member 13
KCNJ14 potassium channel, inwardly rectifying subfamily J, member 14
KCNJ15 potassium channel, inwardly rectifying subfamily J, member 15
KCNJ16 potassium channel, inwardly rectifying subfamily J, member 16
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
KCNJ3 potassium channel, inwardly rectifying subfamily J, member 3
KCNJ4 potassium channel, inwardly rectifying subfamily J, member 4
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5
KCNJ6 potassium channel, inwardly rectifying subfamily J, member 6
KCNJ8 potassium channel, inwardly rectifying subfamily J, member 8
KCNJ9 potassium channel, inwardly rectifying subfamily J, member 9
KCNK1 potassium channel, two pore domain subfamily K, member 1
KCNK6 potassium channel, two pore domain subfamily K, member 6
KCNQ5 potassium channel, voltage gated KQT-like subfamily Q, member 5
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