iobenguane-1729 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the iobenguane-1729 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACAN aggrecan
ADA adenosine deaminase
ADCY6 adenylate cyclase 6
APOC4 apolipoprotein C-IV
ASMTL acetylserotonin O-methyltransferase-like
ATP5SL ATP5S-like
BBC3 BCL2 binding component 3
C9ORF156 chromosome 9 open reading frame 156
C9ORF16 chromosome 9 open reading frame 16
CACNB3 calcium channel, voltage-dependent, beta 3 subunit
CACNG4 calcium channel, voltage-dependent, gamma subunit 4
CBX6 chromobox homolog 6
CCS copper chaperone for superoxide dismutase
CD6 CD6 molecule
CDK12 cyclin-dependent kinase 12
CDK5 cyclin-dependent kinase 5
CDK6 cyclin-dependent kinase 6
CHAF1B chromatin assembly factor 1, subunit B (p60)
CHRM4 cholinergic receptor, muscarinic 4
CLUH clustered mitochondria (cluA/CLU1) homolog
CNTN1 contactin 1
COQ4 coenzyme Q4
CRAT carnitine O-acetyltransferase
CSNK1D casein kinase 1, delta
DPH2 DPH2 homolog (S. cerevisiae)
E2F1 E2F transcription factor 1
E4F1 E4F transcription factor 1
ELK1 ELK1, member of ETS oncogene family
EMC1 ER membrane protein complex subunit 1
EML2 echinoderm microtubule associated protein like 2
EPS8L1 EPS8-like 1
ERI3 ERI1 exoribonuclease family member 3
FAM168B family with sequence similarity 168, member B
FANCF Fanconi anemia, complementation group F
FKBP6 FK506 binding protein 6, 36kDa
FLOT1 flotillin 1
GGA2 golgi-associated, gamma adaptin ear containing, ARF binding protein 2
GLI3 GLI family zinc finger 3
GMDS GDP-mannose 4,6-dehydratase
HDAC5 histone deacetylase 5
HEMK1 HemK methyltransferase family member 1
HFE hemochromatosis
HOOK2 hook microtubule-tethering protein 2
HS6ST1 heparan sulfate 6-O-sulfotransferase 1
HSF2BP heat shock transcription factor 2 binding protein
HUS1 HUS1 checkpoint homolog (S. pombe)
IL5RA interleukin 5 receptor, alpha
IQSEC1 IQ motif and Sec7 domain 1
KIAA0391 KIAA0391
KLF6 Kruppel-like factor 6
LILRB2 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2
LMF2 lipase maturation factor 2
LOC729164 hCG1732469
MADCAM1 mucosal vascular addressin cell adhesion molecule 1
MED14 mediator complex subunit 14
METAP2 methionyl aminopeptidase 2
METRN meteorin, glial cell differentiation regulator
METTL13 methyltransferase like 13
MPDU1 mannose-P-dolichol utilization defect 1
MPPE1 metallophosphoesterase 1
MRPL35 mitochondrial ribosomal protein L35
MST1 macrophage stimulating 1
MYL4 myosin, light chain 4, alkali; atrial, embryonic
NCAPH non-SMC condensin I complex, subunit H
NOC4L nucleolar complex associated 4 homolog (S. cerevisiae)
NOTCH1 notch 1
OGFR opioid growth factor receptor
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PLCB2 phospholipase C, beta 2
PLEK2 pleckstrin 2
PLEKHG3 pleckstrin homology domain containing, family G (with RhoGef domain) member 3
PRDM11 PR domain containing 11
PSG6 pregnancy specific beta-1-glycoprotein 6
PTGDS prostaglandin D2 synthase 21kDa (brain)
RANGAP1 Ran GTPase activating protein 1
REC8 REC8 meiotic recombination protein
RECK reversion-inducing-cysteine-rich protein with kazal motifs
RHOT2 ras homolog family member T2
RITA1 RBPJ interacting and tubulin associated 1
SEC31B SEC31 homolog B (S. cerevisiae)
SLC27A5 solute carrier family 27 (fatty acid transporter), member 5
SLC39A9 solute carrier family 39, member 9
SLC4A2 solute carrier family 4 (anion exchanger), member 2
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SPPL2B signal peptide peptidase like 2B
SRD5A1 steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1)
TBC1D17 TBC1 domain family, member 17
TBC1D30 TBC1 domain family, member 30
TK2 thymidine kinase 2, mitochondrial
TPSG1 tryptase gamma 1
TRGV5 T cell receptor gamma variable 5
TRPV1 transient receptor potential cation channel, subfamily V, member 1
UBE4B ubiquitination factor E4B
WDR13 WD repeat domain 13
YLPM1 YLP motif containing 1
ZC3H13 zinc finger CCCH-type containing 13
ZC3H14 zinc finger CCCH-type containing 14
ZMYND8 zinc finger, MYND-type containing 8

decreased expression

Symbol Name
ABCA11P ATP-binding cassette, sub-family A (ABC1), member 11, pseudogene
ABHD3 abhydrolase domain containing 3
AP5S1 adaptor-related protein complex 5, sigma 1 subunit
APOBR apolipoprotein B receptor
ASAP1-IT1 ASAP1 intronic transcript 1
ATXN2 ataxin 2
BARD1 BRCA1 associated RING domain 1
BATF3 basic leucine zipper transcription factor, ATF-like 3
BMS1 BMS1 ribosome biogenesis factor
BST1 bone marrow stromal cell antigen 1
BTK Bruton agammaglobulinemia tyrosine kinase
C19ORF24 chromosome 19 open reading frame 24
CARM1 coactivator-associated arginine methyltransferase 1
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CCZ1B CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae)
CD82 CD82 molecule
CEP72 centrosomal protein 72kDa
CNPY3 canopy FGF signaling regulator 3
COMMD10 COMM domain containing 10
CRYBG3 beta-gamma crystallin domain containing 3
CRYL1 crystallin, lambda 1
DCLRE1B DNA cross-link repair 1B
DCPS decapping enzyme, scavenger
DDX39A DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
DFFA DNA fragmentation factor, 45kDa, alpha polypeptide
DNAJB14 DnaJ (Hsp40) homolog, subfamily B, member 14
DRAP1 DR1-associated protein 1 (negative cofactor 2 alpha)
DUSP11 dual specificity phosphatase 11 (RNA/RNP complex 1-interacting)
ELSPBP1 epididymal sperm binding protein 1
FCHO1 FCH domain only 1
GAB2 GRB2-associated binding protein 2
GADD45A growth arrest and DNA-damage-inducible, alpha
GPATCH2 G patch domain containing 2
GTF2F2 general transcription factor IIF, polypeptide 2, 30kDa
HAGH hydroxyacylglutathione hydrolase
HAUS7 HAUS augmin-like complex, subunit 7
HIRA histone cell cycle regulator
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
JRKL JRK-like
KCTD15 potassium channel tetramerization domain containing 15
KIFC1 kinesin family member C1
LMO4 LIM domain only 4
LOC202181 SUMO-interacting motifs containing 1 pseudogene
MCM10 minichromosome maintenance complex component 10
MCRS1 microspherule protein 1
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
MT1HL1 metallothionein 1H-like 1
MTG1 mitochondrial ribosome-associated GTPase 1
MTHFS 5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase)
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NEDD8 neural precursor cell expressed, developmentally down-regulated 8
NIP7 NIP7, nucleolar pre-rRNA processing protein
NT5E 5'-nucleotidase, ecto (CD73)
OGDH oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
OVGP1 oviductal glycoprotein 1, 120kDa
OXSR1 oxidative stress responsive 1
PDSS2 prenyl (decaprenyl) diphosphate synthase, subunit 2
PLA2G12A phospholipase A2, group XIIA
PPRC1 peroxisome proliferator-activated receptor gamma, coactivator-related 1
PSKH1 protein serine kinase H1
RAB8B RAB8B, member RAS oncogene family
RSL24D1 ribosomal L24 domain containing 1
SART1 squamous cell carcinoma antigen recognized by T cells
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
SNX6 sorting nexin 6
SPA17 sperm autoantigenic protein 17
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
SRBD1 S1 RNA binding domain 1
STAR steroidogenic acute regulatory protein
STK39 serine threonine kinase 39
TAC3 tachykinin 3
TACC3 transforming, acidic coiled-coil containing protein 3
TCTN2 tectonic family member 2
TOMM22 translocase of outer mitochondrial membrane 22 homolog (yeast)
TPCN1 two pore segment channel 1
TRHDE thyrotropin-releasing hormone degrading enzyme
TRIM9 tripartite motif containing 9
TRPM2 transient receptor potential cation channel, subfamily M, member 2
TSPAN32 tetraspanin 32
TTC4 tetratricopeptide repeat domain 4
UBXN2B UBX domain protein 2B
UGDH UDP-glucose 6-dehydrogenase
UXS1 UDP-glucuronate decarboxylase 1
WBP2 WW domain binding protein 2
WBSCR16 Williams-Beuren syndrome chromosome region 16
XYLT1 xylosyltransferase I
YARS2 tyrosyl-tRNA synthetase 2, mitochondrial
ZCCHC8 zinc finger, CCHC domain containing 8
ZNF217 zinc finger protein 217
ZNF273 zinc finger protein 273
ZNF280D zinc finger protein 280D
ZNF350 zinc finger protein 350
ZNF468 zinc finger protein 468
ZNF804A zinc finger protein 804A
ZNRD1-AS1 ZNRD1 antisense RNA 1
ZW10 zw10 kinetochore protein