iobenguane-2878 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the iobenguane-2878 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADH7 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
ALCAM activated leukocyte cell adhesion molecule
ALDOB aldolase B, fructose-bisphosphate
APC adenomatous polyposis coli
APOBEC2 apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2
ATM ATM serine/threonine kinase
ATP6V0A4 ATPase, H+ transporting, lysosomal V0 subunit a4
BAIAP3 BAI1-associated protein 3
BMP5 bone morphogenetic protein 5
C10ORF95 chromosome 10 open reading frame 95
C8A complement component 8, alpha polypeptide
C8ORF60 chromosome 8 open reading frame 60
CAV2 caveolin 2
CD209 CD209 molecule
CDC14A cell division cycle 14A
CDK14 cyclin-dependent kinase 14
CIDEB cell death-inducing DFFA-like effector b
CIITA class II, major histocompatibility complex, transactivator
COL1A1 collagen, type I, alpha 1
CPB2 carboxypeptidase B2 (plasma)
DLX2 distal-less homeobox 2
DMXL2 Dmx-like 2
ERCC2 excision repair cross-complementation group 2
ERCC6 excision repair cross-complementation group 6
FAM174B family with sequence similarity 174, member B
FAM49B family with sequence similarity 49, member B
FBXO2 F-box protein 2
FKBP8 FK506 binding protein 8, 38kDa
GDF5 growth differentiation factor 5
GLDC glycine dehydrogenase (decarboxylating)
GPATCH4 G patch domain containing 4
GRIK5 glutamate receptor, ionotropic, kainate 5
HCN2 hyperpolarization activated cyclic nucleotide gated potassium channel 2
HFE hemochromatosis
HOXA10 homeobox A10
HSD3B1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1
ICA1 islet cell autoantigen 1, 69kDa
IL11 interleukin 11
IRS4 insulin receptor substrate 4
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KLHL20 kelch-like family member 20
KLHL25 kelch-like family member 25
KLK1 kallikrein 1
LARP6 La ribonucleoprotein domain family, member 6
LINC00597 long intergenic non-protein coding RNA 597
LLPH LLP homolog, long-term synaptic facilitation (Aplysia)
MARS methionyl-tRNA synthetase
MBTD1 mbt domain containing 1
METTL7A methyltransferase like 7A
MOCS1 molybdenum cofactor synthesis 1
MYH14 myosin, heavy chain 14, non-muscle
NAALAD2 N-acetylated alpha-linked acidic dipeptidase 2
NCKIPSD NCK interacting protein with SH3 domain
NDUFA5 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5
NF1 neurofibromin 1
OCLM oculomedin
OR2B6 olfactory receptor, family 2, subfamily B, member 6
ORAI2 ORAI calcium release-activated calcium modulator 2
PCDHB3 protocadherin beta 3
PIDD1 p53-induced death domain protein 1
PLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent)
PMS2P3 postmeiotic segregation increased 2 pseudogene 3
POM121L2 POM121 transmembrane nucleoporin-like 2
PPFIBP2 PTPRF interacting protein, binding protein 2 (liprin beta 2)
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
RAD52 RAD52 homolog (S. cerevisiae)
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2
RARA retinoic acid receptor, alpha
RND1 Rho family GTPase 1
RREB1 ras responsive element binding protein 1
S100A2 S100 calcium binding protein A2
SAFB scaffold attachment factor B
SAYSD1 SAYSVFN motif domain containing 1
SDC2 syndecan 2
SERPINA7 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7
SLC44A1 solute carrier family 44 (choline transporter), member 1
SLC9A7 solute carrier family 9, subfamily A (NHE7, cation proton antiporter 7), member 7
SPDEF SAM pointed domain containing ETS transcription factor
SPPL2B signal peptide peptidase like 2B
SPRR1B small proline-rich protein 1B
SPTLC2 serine palmitoyltransferase, long chain base subunit 2
SRSF7 serine/arginine-rich splicing factor 7
STIM1 stromal interaction molecule 1
STS steroid sulfatase (microsomal), isozyme S
SZT2 seizure threshold 2 homolog (mouse)
TEF thyrotrophic embryonic factor
TEP1 telomerase-associated protein 1
TGFB2 transforming growth factor, beta 2
TM2D1 TM2 domain containing 1
TMC6 transmembrane channel-like 6
UBTD1 ubiquitin domain containing 1
UHRF1BP1L UHRF1 binding protein 1-like
UPF3A UPF3 regulator of nonsense transcripts homolog A (yeast)
VAV2 vav 2 guanine nucleotide exchange factor
YY1 YY1 transcription factor
ZMAT4 zinc finger, matrin-type 4
ZMIZ2 zinc finger, MIZ-type containing 2
ZNF197 zinc finger protein 197
ZNF652 zinc finger protein 652
ZSCAN18 zinc finger and SCAN domain containing 18

decreased expression

Symbol Name
ABI3BP ABI family, member 3 (NESH) binding protein
ABLIM3 actin binding LIM protein family, member 3
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
ALG12 ALG12, alpha-1,6-mannosyltransferase
ARID3B AT rich interactive domain 3B (BRIGHT-like)
B4GALT2 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
C3 complement component 3
CCDC85C coiled-coil domain containing 85C
CEP112 centrosomal protein 112kDa
CEP97 centrosomal protein 97kDa
CLCN2 chloride channel, voltage-sensitive 2
CLIP4 CAP-GLY domain containing linker protein family, member 4
CNNM2 cyclin and CBS domain divalent metal cation transport mediator 2
CRELD1 cysteine-rich with EGF-like domains 1
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
CXXC4 CXXC finger protein 4
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
DGAT1 diacylglycerol O-acyltransferase 1
DHRS3 dehydrogenase/reductase (SDR family) member 3
DNALI1 dynein, axonemal, light intermediate chain 1
DNM1 dynamin 1
DVL1 dishevelled segment polarity protein 1
EFNA3 ephrin-A3
EPHA2 EPH receptor A2
ERN2 endoplasmic reticulum to nucleus signaling 2
ETV6 ets variant 6
FOSL1 FOS-like antigen 1
GADD45G growth arrest and DNA-damage-inducible, gamma
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GMIP GEM interacting protein
GNA12 guanine nucleotide binding protein (G protein) alpha 12
GPATCH3 G patch domain containing 3
HEY2 hes-related family bHLH transcription factor with YRPW motif 2
HIST1H2AJ histone cluster 1, H2aj
HNRNPA3P1 heterogeneous nuclear ribonucleoprotein A3 pseudogene 1
HOXC13 homeobox C13
HOXC4 homeobox C4
HSD17B1 hydroxysteroid (17-beta) dehydrogenase 1
HYI hydroxypyruvate isomerase (putative)
IFT140 intraflagellar transport 140
IL17RA interleukin 17 receptor A
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
LOC729164 hCG1732469
LRRC37A2 leucine rich repeat containing 37, member A2
LY6D lymphocyte antigen 6 complex, locus D
LYPD1 LY6/PLAUR domain containing 1
MAP3K6 mitogen-activated protein kinase kinase kinase 6
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1
NAV2 neuron navigator 2
NEK11 NIMA-related kinase 11
NRSN2 neurensin 2
NXPE3 neurexophilin and PC-esterase domain family, member 3
OSMR oncostatin M receptor
PACS1 phosphofurin acidic cluster sorting protein 1
PAFAH1B2 platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa)
PHF14 PHD finger protein 14
PLCD1 phospholipase C, delta 1
PLEKHA6 pleckstrin homology domain containing, family A member 6
PLEKHO2 pleckstrin homology domain containing, family O member 2
POM121 POM121 transmembrane nucleoporin
PRPH peripherin
RIN2 Ras and Rab interactor 2
RNF170 ring finger protein 170
RNF2 ring finger protein 2
RPL10L ribosomal protein L10-like
RPL13P5 ribosomal protein L13 pseudogene 5
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4
RYR1 ryanodine receptor 1 (skeletal)
SETD1A SET domain containing 1A
SH2B2 SH2B adaptor protein 2
SLC12A8 solute carrier family 12, member 8
SRD5A3 steroid 5 alpha-reductase 3
TAOK1 TAO kinase 1
TBC1D19 TBC1 domain family, member 19
TBX19 T-box 19
TH tyrosine hydroxylase
THOP1 thimet oligopeptidase 1
TLR2 toll-like receptor 2
TM6SF1 transmembrane 6 superfamily member 1
TOM1 target of myb1 (chicken)
TRIM21 tripartite motif containing 21
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TUBA3C tubulin, alpha 3c
TYRP1 tyrosinase-related protein 1
USB1 U6 snRNA biogenesis 1
USP6NL USP6 N-terminal like
VASH2 vasohibin 2
XAB2 XPA binding protein 2
ZC3H3 zinc finger CCCH-type containing 3
ZNF204P zinc finger protein 204, pseudogene
ZNF205 zinc finger protein 205
ZNF282 zinc finger protein 282
ZNF34 zinc finger protein 34
ZNF350 zinc finger protein 350
ZNF41 zinc finger protein 41
ZSCAN2 zinc finger and SCAN domain containing 2