iobenguane-7299 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

194 genes differentially expressed following the iobenguane-7299 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCC6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6
ACADSB acyl-CoA dehydrogenase, short/branched chain
ACSL5 acyl-CoA synthetase long-chain family member 5
ARID3A AT rich interactive domain 3A (BRIGHT-like)
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
BIN1 bridging integrator 1
CAV2 caveolin 2
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CCPG1 cell cycle progression 1
CCSER2 coiled-coil serine-rich protein 2
CDK3 cyclin-dependent kinase 3
CFAP69 cilia and flagella associated protein 69
CHI3L2 chitinase 3-like 2
COL7A1 collagen, type VII, alpha 1
CUZD1 CUB and zona pellucida-like domains 1
DAGLA diacylglycerol lipase, alpha
DIO2 deiodinase, iodothyronine, type II
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
EDNRA endothelin receptor type A
EPHA7 EPH receptor A7
EPM2A epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)
FBXL15 F-box and leucine-rich repeat protein 15
FCMR Fc fragment of IgM receptor
FLJ11292
GGA2 golgi-associated, gamma adaptin ear containing, ARF binding protein 2
GSK3A glycogen synthase kinase 3 alpha
HABP4 hyaluronan binding protein 4
HIP1 huntingtin interacting protein 1
HIST1H1D histone cluster 1, H1d
HIST2H2AA3 histone cluster 2, H2aa3
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
IGSF3 immunoglobulin superfamily, member 3
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa
KCNAB2 potassium channel, voltage gated subfamily A regulatory beta subunit 2
KDM4C lysine (K)-specific demethylase 4C
KIAA0485 uncharacterized LOC57235
LIMK2 LIM domain kinase 2
LRP1 low density lipoprotein receptor-related protein 1
LRRC61 leucine rich repeat containing 61
MARS methionyl-tRNA synthetase
MFAP3L microfibrillar-associated protein 3-like
MGAT2 mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
MMP15 matrix metallopeptidase 15 (membrane-inserted)
MTMR3 myotubularin related protein 3
MUC7 mucin 7, secreted
NOTCH4 notch 4
NPC1 Niemann-Pick disease, type C1
NPFFR1 neuropeptide FF receptor 1
NR4A1 nuclear receptor subfamily 4, group A, member 1
NR4A2 nuclear receptor subfamily 4, group A, member 2
OVGP1 oviductal glycoprotein 1, 120kDa
PAK6 p21 protein (Cdc42/Rac)-activated kinase 6
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PIGQ phosphatidylinositol glycan anchor biosynthesis, class Q
PLCH2 phospholipase C, eta 2
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PRPH peripherin
PWAR5 Prader Willi/Angelman region RNA 5
RAD51B RAD51 paralog B
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5
RARA retinoic acid receptor, alpha
RARRES3 retinoic acid receptor responder (tazarotene induced) 3
RPGRIP1L RPGRIP1-like
S100A3 S100 calcium binding protein A3
SAYSD1 SAYSVFN motif domain containing 1
SEC61A2 Sec61 alpha 2 subunit (S. cerevisiae)
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2
SMAD1 SMAD family member 1
SMURF1 SMAD specific E3 ubiquitin protein ligase 1
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SOGA1 suppressor of glucose, autophagy associated 1
SOX2 SRY (sex determining region Y)-box 2
STAC SH3 and cysteine rich domain
STAG3 stromal antigen 3
STAG3L4 stromal antigen 3-like 4 (pseudogene)
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1
SYT11 synaptotagmin XI
TRIO trio Rho guanine nucleotide exchange factor
TSNAXIP1 translin-associated factor X interacting protein 1
TUBA3C tubulin, alpha 3c
TUSC3 tumor suppressor candidate 3
UBXN1 UBX domain protein 1
VCX2 variable charge, X-linked 2
WNT10B wingless-type MMTV integration site family, member 10B
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase
ZBTB7A zinc finger and BTB domain containing 7A
ZC3H7B zinc finger CCCH-type containing 7B
ZNF137P zinc finger protein 137, pseudogene
ZNF222 zinc finger protein 222
ZNF280A zinc finger protein 280A
ZNF41 zinc finger protein 41
ZNF480 zinc finger protein 480
ZNF778 zinc finger protein 778
ZNF783 zinc finger family member 783

decreased expression

Symbol Name
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
ANG angiogenin, ribonuclease, RNase A family, 5
ANKZF1 ankyrin repeat and zinc finger domain containing 1
ANXA2P3 annexin A2 pseudogene 3
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1
AXIN1 axin 1
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
BBS7 Bardet-Biedl syndrome 7
BCAS4 breast carcinoma amplified sequence 4
BHLHB9 basic helix-loop-helix domain containing, class B, 9
BOLA1 bolA family member 1
BPGM 2,3-bisphosphoglycerate mutase
BSPRY B-box and SPRY domain containing
C1ORF35 chromosome 1 open reading frame 35
C9ORF114 chromosome 9 open reading frame 114
CAMTA2 calmodulin binding transcription activator 2
CAPN15 calpain 15
CGREF1 cell growth regulator with EF-hand domain 1
CHCHD7 coiled-coil-helix-coiled-coil-helix domain containing 7
CHMP6 charged multivesicular body protein 6
COLGALT2 collagen beta(1-O)galactosyltransferase 2
CRIP1 cysteine-rich protein 1 (intestinal)
CTSO cathepsin O
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DEF6 differentially expressed in FDCP 6 homolog (mouse)
DLK1 delta-like 1 homolog (Drosophila)
DTX4 deltex 4, E3 ubiquitin ligase
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
EIF5A2 eukaryotic translation initiation factor 5A2
EMC9 ER membrane protein complex subunit 9
EVPL envoplakin
FAM50B family with sequence similarity 50, member B
FANCE Fanconi anemia, complementation group E
GUCY1A3 guanylate cyclase 1, soluble, alpha 3
HHLA3 HERV-H LTR-associating 3
HIST1H2AG histone cluster 1, H2ag
HIST1H3H histone cluster 1, H3h
HSD3B2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2
INF2 inverted formin, FH2 and WH2 domain containing
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
KDM5C lysine (K)-specific demethylase 5C
L2HGDH L-2-hydroxyglutarate dehydrogenase
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
LINC00339 long intergenic non-protein coding RNA 339
MAP6D1 MAP6 domain containing 1
MBIP MAP3K12 binding inhibitory protein 1
MBTPS2 membrane-bound transcription factor peptidase, site 2
METRN meteorin, glial cell differentiation regulator
MICALL2 MICAL-like 2
MMACHC methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria
MOGS mannosyl-oligosaccharide glucosidase
MON1B MON1 secretory trafficking family member B
MOSPD3 motile sperm domain containing 3
NARFL nuclear prelamin A recognition factor-like
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon
NLRX1 NLR family member X1
NME5 NME/NM23 family member 5
NXPH4 neurexophilin 4
PCSK7 proprotein convertase subtilisin/kexin type 7
PEX26 peroxisomal biogenesis factor 26
PHKG2 phosphorylase kinase, gamma 2 (testis)
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
POLM polymerase (DNA directed), mu
PORCN porcupine homolog (Drosophila)
PPP2R3B protein phosphatase 2, regulatory subunit B'', beta
PPT2 palmitoyl-protein thioesterase 2
PTPN14 protein tyrosine phosphatase, non-receptor type 14
RNF219 ring finger protein 219
RPL13P5 ribosomal protein L13 pseudogene 5
SH3TC2 SH3 domain and tetratricopeptide repeats 2
SIPA1 signal-induced proliferation-associated 1
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1
SNIP1 Smad nuclear interacting protein 1
SNX24 sorting nexin 24
SREBF1 sterol regulatory element binding transcription factor 1
STAR steroidogenic acute regulatory protein
STARD13 StAR-related lipid transfer (START) domain containing 13
SYNPO synaptopodin
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TBC1D19 TBC1 domain family, member 19
THBS3 thrombospondin 3
TMEM159 transmembrane protein 159
TMEM183A transmembrane protein 183A
TPCN1 two pore segment channel 1
TRIM66 tripartite motif containing 66
UBQLN4 ubiquilin 4
USP27X ubiquitin specific peptidase 27, X-linked
USP32 ubiquitin specific peptidase 32
WDR46 WD repeat domain 46
XAB2 XPA binding protein 2
XPNPEP3 X-prolyl aminopeptidase 3, mitochondrial
ZFHX3 zinc finger homeobox 3
ZNF34 zinc finger protein 34
ZNF350 zinc finger protein 350