iocetamic acid-3022 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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197 genes differentially expressed following the iocetamic acid-3022 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACE angiotensin I converting enzyme
ACTA2 actin, alpha 2, smooth muscle, aorta
ADAM12 ADAM metallopeptidase domain 12
AIPL1 aryl hydrocarbon receptor interacting protein-like 1
AKAP4 A kinase (PRKA) anchor protein 4
APOA1 apolipoprotein A-I
APPBP2 amyloid beta precursor protein (cytoplasmic tail) binding protein 2
C8ORF4 chromosome 8 open reading frame 4
CACNA1I calcium channel, voltage-dependent, T type, alpha 1I subunit
CALD1 caldesmon 1
CCDC88C coiled-coil domain containing 88C
CCSER2 coiled-coil serine-rich protein 2
CD300C CD300c molecule
CD7 CD7 molecule
CDK2 cyclin-dependent kinase 2
CEACAM21 carcinoembryonic antigen-related cell adhesion molecule 21
CHMP6 charged multivesicular body protein 6
CMAHP cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene
COPE coatomer protein complex, subunit epsilon
CPN2 carboxypeptidase N, polypeptide 2
CXCL3 chemokine (C-X-C motif) ligand 3
CYP4F11 cytochrome P450, family 4, subfamily F, polypeptide 11
DCN decorin
DDR1 discoidin domain receptor tyrosine kinase 1
DEFA4 defensin, alpha 4, corticostatin
DUSP7 dual specificity phosphatase 7
EXT1 exostosin glycosyltransferase 1
FAM120C family with sequence similarity 120C
FAM127B family with sequence similarity 127, member B
FARP1 FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
GFER growth factor, augmenter of liver regeneration
GLRA2 glycine receptor, alpha 2
GMPR guanosine monophosphate reductase
GNB3 guanine nucleotide binding protein (G protein), beta polypeptide 3
GRIA3 glutamate receptor, ionotropic, AMPA 3
HDGFRP3 hepatoma-derived growth factor, related protein 3
HIST1H2BC histone cluster 1, H2bc
HIST1H4F histone cluster 1, H4f
KIF1A kinesin family member 1A
KLHL22 kelch-like family member 22
KLHL3 kelch-like family member 3
KLK5 kallikrein-related peptidase 5
LECT1 leukocyte cell derived chemotaxin 1
LEP leptin
LHPP phospholysine phosphohistidine inorganic pyrophosphate phosphatase
LIMD2 LIM domain containing 2
LLGL1 lethal giant larvae homolog 1 (Drosophila)
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MED27 mediator complex subunit 27
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2
MIR22HG MIR22 host gene
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
MYOM1 myomesin 1
NBR2 neighbor of BRCA1 gene 2 (non-protein coding)
NMT1 N-myristoyltransferase 1
ONECUT1 one cut homeobox 1
OSGIN2 oxidative stress induced growth inhibitor family member 2
PCDHGA8 protocadherin gamma subfamily A, 8
PDE4D phosphodiesterase 4D, cAMP-specific
PDLIM4 PDZ and LIM domain 4
PDPN podoplanin
PER1 period circadian clock 1
PIK3C2G phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 gamma
PMEPA1 prostate transmembrane protein, androgen induced 1
PMS2P3 postmeiotic segregation increased 2 pseudogene 3
POLR2L polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
PPP1R1A protein phosphatase 1, regulatory (inhibitor) subunit 1A
PSG11 pregnancy specific beta-1-glycoprotein 11
RAP1GAP RAP1 GTPase activating protein
RAPGEF1 Rap guanine nucleotide exchange factor (GEF) 1
RGS1 regulator of G-protein signaling 1
RHO rhodopsin
RNGTT RNA guanylyltransferase and 5'-phosphatase
RPL7 ribosomal protein L7
SCIN scinderin
SEC14L4 SEC14-like 4 (S. cerevisiae)
SERHL2 serine hydrolase-like 2
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SHOX2 short stature homeobox 2
SIGLEC1 sialic acid binding Ig-like lectin 1, sialoadhesin
SLC6A20 solute carrier family 6 (proline IMINO transporter), member 20
SLCO1B3 solute carrier organic anion transporter family, member 1B3
SNX13 sorting nexin 13
STK3 serine/threonine kinase 3
STRN3 striatin, calmodulin binding protein 3
TAPT1 transmembrane anterior posterior transformation 1
TNFRSF17 tumor necrosis factor receptor superfamily, member 17
TNNT3 troponin T type 3 (skeletal, fast)
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
WDR55 WD repeat domain 55
WISP3 WNT1 inducible signaling pathway protein 3
WWTR1 WW domain containing transcription regulator 1
ZBTB17 zinc finger and BTB domain containing 17
ZC3H7B zinc finger CCCH-type containing 7B
ZNF225 zinc finger protein 225
ZNF32 zinc finger protein 32

decreased expression

Symbol Name
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
ADAM3A ADAM metallopeptidase domain 3A (pseudogene)
ADGRB1 adhesion G protein-coupled receptor B1
AFF4 AF4/FMR2 family, member 4
ALOX15B arachidonate 15-lipoxygenase, type B
ANXA2P3 annexin A2 pseudogene 3
B4GALNT1 beta-1,4-N-acetyl-galactosaminyl transferase 1
BTBD18 BTB (POZ) domain containing 18
BTF3P11 basic transcription factor 3 pseudogene 11
CAMTA1 calmodulin binding transcription activator 1
CCDC186 coiled-coil domain containing 186
CCDC71 coiled-coil domain containing 71
CD79B CD79b molecule, immunoglobulin-associated beta
CDKL3 cyclin-dependent kinase-like 3
CHGA chromogranin A
CISH cytokine inducible SH2-containing protein
CLCN2 chloride channel, voltage-sensitive 2
CLGN calmegin
CNGB3 cyclic nucleotide gated channel beta 3
COL9A3 collagen, type IX, alpha 3
COPG2IT1 COPG2 imprinted transcript 1 (non-protein coding)
CPTP ceramide-1-phosphate transfer protein
CROT carnitine O-octanoyltransferase
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2
GATA4 GATA binding protein 4
GEM GTP binding protein overexpressed in skeletal muscle
GNG3 guanine nucleotide binding protein (G protein), gamma 3
GPR35 G protein-coupled receptor 35
GRPR gastrin-releasing peptide receptor
HDAC7 histone deacetylase 7
HIST1H3I histone cluster 1, H3i
HOXA5 homeobox A5
HOXB9 homeobox B9
HOXC10 homeobox C10
HOXD10 homeobox D10
IBSP integrin-binding sialoprotein
IFT22 intraflagellar transport 22
JPH3 junctophilin 3
KCNK12 potassium channel, two pore domain subfamily K, member 12
LEFTY2 left-right determination factor 2
LHX2 LIM homeobox 2
LIN7A lin-7 homolog A (C. elegans)
LPAR3 lysophosphatidic acid receptor 3
MAP3K14 mitogen-activated protein kinase kinase kinase 14
MAP6D1 MAP6 domain containing 1
MKL2 MKL/myocardin-like 2
MNS1 meiosis-specific nuclear structural 1
MYH15 myosin, heavy chain 15
NDE1 nudE neurodevelopment protein 1
NEUROD1 neuronal differentiation 1
NOL10 nucleolar protein 10
NXF2 nuclear RNA export factor 2
OCA2 oculocutaneous albinism II
OXCT2 3-oxoacid CoA transferase 2
PADI1 peptidyl arginine deiminase, type I
PARP12 poly (ADP-ribose) polymerase family, member 12
PDE11A phosphodiesterase 11A
PDE7B phosphodiesterase 7B
PDGFRL platelet-derived growth factor receptor-like
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PNPLA3 patatin-like phospholipase domain containing 3
POLH polymerase (DNA directed), eta
PP14571 uncharacterized LOC100130449
PYGB phosphorylase, glycogen; brain
RAB13 RAB13, member RAS oncogene family
RAB33A RAB33A, member RAS oncogene family
RAB3D RAB3D, member RAS oncogene family
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2
RIBC2 RIB43A domain with coiled-coils 2
RPL23AP32 ribosomal protein L23a pseudogene 32
RSPH14 radial spoke head 14 homolog (Chlamydomonas)
RWDD2A RWD domain containing 2A
SCRT1 scratch family zinc finger 1
SCUBE3 signal peptide, CUB domain, EGF-like 3
SFRP5 secreted frizzled-related protein 5
SH3GLB2 SH3-domain GRB2-like endophilin B2
SKIV2L superkiller viralicidic activity 2-like (S. cerevisiae)
SLC17A2 solute carrier family 17, member 2
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SNAI1 snail family zinc finger 1
SPTBN5 spectrin, beta, non-erythrocytic 5
SRD5A2 steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2)
STATH statherin
SYCP2 synaptonemal complex protein 2
TBX21 T-box 21
TMEM120B transmembrane protein 120B
TNNT1 troponin T type 1 (skeletal, slow)
TPSB2 tryptase beta 2 (gene/pseudogene)
TTC30A tetratricopeptide repeat domain 30A
UNC13A unc-13 homolog A (C. elegans)
USP18 ubiquitin specific peptidase 18
VPREB1 pre-B lymphocyte 1
VWA1 von Willebrand factor A domain containing 1
YPEL1 yippee-like 1 (Drosophila)
ZNF385D zinc finger protein 385D
ZNF41 zinc finger protein 41
ZNF484 zinc finger protein 484