iocetamic acid-4600 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the iocetamic acid-4600 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAM2 ADAM metallopeptidase domain 2
ADRA1D adrenoceptor alpha 1D
AKAP8L A kinase (PRKA) anchor protein 8-like
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
B4GALT1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
BBS9 Bardet-Biedl syndrome 9
BCAS1 breast carcinoma amplified sequence 1
C10ORF10 chromosome 10 open reading frame 10
C11ORF63 chromosome 11 open reading frame 63
C21ORF2 chromosome 21 open reading frame 2
C2CD2L C2CD2-like
CASP8 caspase 8, apoptosis-related cysteine peptidase
CCP110 centriolar coiled coil protein 110kDa
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDK20 cyclin-dependent kinase 20
CLCN4 chloride channel, voltage-sensitive 4
CLEC11A C-type lectin domain family 11, member A
COBLL1 cordon-bleu WH2 repeat protein-like 1
CREM cAMP responsive element modulator
CTIF CBP80/20-dependent translation initiation factor
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
DCSTAMP dendrocyte expressed seven transmembrane protein
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
DLC1 DLC1 Rho GTPase activating protein
DMP1 dentin matrix acidic phosphoprotein 1
DMPK dystrophia myotonica-protein kinase
DUSP1 dual specificity phosphatase 1
EYA3 EYA transcriptional coactivator and phosphatase 3
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2
GIF gastric intrinsic factor (vitamin B synthesis)
GK glycerol kinase
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GPSM3 G-protein signaling modulator 3
HEMK1 HemK methyltransferase family member 1
HIF3A hypoxia inducible factor 3, alpha subunit
HIST1H2AK histone cluster 1, H2ak
IL6 interleukin 6
ING4 inhibitor of growth family, member 4
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1
KLHL22 kelch-like family member 22
KLK7 kallikrein-related peptidase 7
KRIT1 KRIT1, ankyrin repeat containing
KRT9 keratin 9, type I
LARGE like-glycosyltransferase
MAP7 microtubule-associated protein 7
MAP7D3 MAP7 domain containing 3
MARK2 MAP/microtubule affinity-regulating kinase 2
MET MET proto-oncogene, receptor tyrosine kinase
MTA2 metastasis associated 1 family, member 2
MTMR1 myotubularin related protein 1
MYOZ3 myozenin 3
NCOA2 nuclear receptor coactivator 2
NEK9 NIMA-related kinase 9
NF1 neurofibromin 1
NFRKB nuclear factor related to kappaB binding protein
NOTCH2 notch 2
OLFML2B olfactomedin-like 2B
OR2B6 olfactory receptor, family 2, subfamily B, member 6
PALM paralemmin
PBX2 pre-B-cell leukemia homeobox 2
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor)
PDE4DIP phosphodiesterase 4D interacting protein
PGP phosphoglycolate phosphatase
PI4K2A phosphatidylinositol 4-kinase type 2 alpha
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PITX1 paired-like homeodomain 1
PLEK pleckstrin
POFUT1 protein O-fucosyltransferase 1
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
PRKCE protein kinase C, epsilon
RAB28 RAB28, member RAS oncogene family
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
REEP1 receptor accessory protein 1
RIMBP2 RIMS binding protein 2
RNF6 ring finger protein (C3H2C3 type) 6
RORA RAR-related orphan receptor A
RQCD1 RCD1 required for cell differentiation1 homolog (S. pombe)
RUNX1 runt-related transcription factor 1
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SEC14L4 SEC14-like 4 (S. cerevisiae)
SEC23A Sec23 homolog A (S. cerevisiae)
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7
SLCO1B1 solute carrier organic anion transporter family, member 1B1
SOS2 son of sevenless homolog 2 (Drosophila)
SPPL2B signal peptide peptidase like 2B
SRSF5 serine/arginine-rich splicing factor 5
STAT2 signal transducer and activator of transcription 2, 113kDa
STS steroid sulfatase (microsomal), isozyme S
TAF1C TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa
TGFA transforming growth factor, alpha
TNS1 tensin 1
TOR1AIP1 torsin A interacting protein 1
TRMT44 tRNA methyltransferase 44 homolog (S. cerevisiae)
TYMS thymidylate synthetase
UCP3 uncoupling protein 3 (mitochondrial, proton carrier)
UGT2B15 UDP glucuronosyltransferase 2 family, polypeptide B15
VPS53 vacuolar protein sorting 53 homolog (S. cerevisiae)
YIF1B Yip1 interacting factor homolog B (S. cerevisiae)
ZFX zinc finger protein, X-linked
ZKSCAN8 zinc finger with KRAB and SCAN domains 8

decreased expression

Symbol Name
ACADSB acyl-CoA dehydrogenase, short/branched chain
ACE angiotensin I converting enzyme
ACSL5 acyl-CoA synthetase long-chain family member 5
ADGRB2 adhesion G protein-coupled receptor B2
ALPK1 alpha-kinase 1
AOC2 amine oxidase, copper containing 2 (retina-specific)
APOLD1 apolipoprotein L domain containing 1
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ARL14 ADP-ribosylation factor-like 14
BEX1 brain expressed, X-linked 1
BTF3P12 basic transcription factor 3 pseudogene 12
C14ORF93 chromosome 14 open reading frame 93
C17ORF53 chromosome 17 open reading frame 53
C7ORF43 chromosome 7 open reading frame 43
CAPN15 calpain 15
CES3 carboxylesterase 3
CIR1 corepressor interacting with RBPJ, 1
CISH cytokine inducible SH2-containing protein
CLCN6 chloride channel, voltage-sensitive 6
CLSTN3 calsyntenin 3
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4
CNTNAP1 contactin associated protein 1
CPEB1 cytoplasmic polyadenylation element binding protein 1
CPNE7 copine VII
CPZ carboxypeptidase Z
CSF1R colony stimulating factor 1 receptor
CTC1 CTS telomere maintenance complex component 1
CTSF cathepsin F
DAGLA diacylglycerol lipase, alpha
EN1 engrailed homeobox 1
ERMAP erythroblast membrane-associated protein (Scianna blood group)
ERN2 endoplasmic reticulum to nucleus signaling 2
FBXO46 F-box protein 46
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32)
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group)
GAS8 growth arrest-specific 8
GUCY1B2 guanylate cyclase 1, soluble, beta 2 (pseudogene)
HIST1H1D histone cluster 1, H1d
HOXC8 homeobox C8
HSPA1L heat shock 70kDa protein 1-like
IL7 interleukin 7
INPPL1 inositol polyphosphate phosphatase-like 1
IRF1 interferon regulatory factor 1
ITPKA inositol-trisphosphate 3-kinase A
KLF13 Kruppel-like factor 13
LAMC3 laminin, gamma 3
LINS lines homolog (Drosophila)
LMNB1 lamin B1
LRRC61 leucine rich repeat containing 61
MAGEA6 melanoma antigen family A6
MDFI MyoD family inhibitor
MMRN2 multimerin 2
MTERF4 mitochondrial transcription termination factor 4
MUC3B mucin 3B, cell surface associated
MX1 MX dynamin-like GTPase 1
MXD3 MAX dimerization protein 3
NME5 NME/NM23 family member 5
OVGP1 oviductal glycoprotein 1, 120kDa
P2RX5 purinergic receptor P2X, ligand gated ion channel, 5
PACS1 phosphofurin acidic cluster sorting protein 1
PAK3 p21 protein (Cdc42/Rac)-activated kinase 3
PDE12 phosphodiesterase 12
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PLAC8 placenta-specific 8
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
POMT2 protein-O-mannosyltransferase 2
PRF1 perforin 1 (pore forming protein)
PRRG2 proline rich Gla (G-carboxyglutamic acid) 2
RNF126P1 ring finger protein 126 pseudogene 1
RNF39 ring finger protein 39
RPGRIP1L RPGRIP1-like
RPP25 ribonuclease P/MRP 25kDa subunit
SAMD9 sterile alpha motif domain containing 9
SAYSD1 SAYSVFN motif domain containing 1
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SH2D2A SH2 domain containing 2A
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2
SLMO1 slowmo homolog 1 (Drosophila)
SPTLC3 serine palmitoyltransferase, long chain base subunit 3
SYNGR3 synaptogyrin 3
TMEM212 transmembrane protein 212
TNK1 tyrosine kinase, non-receptor, 1
TSKU tsukushi, small leucine rich proteoglycan
TUBA3C tubulin, alpha 3c
TUBB2B tubulin, beta 2B class IIb
UAP1L1 UDP-N-acetylglucosamine pyrophosphorylase 1 like 1
VGF VGF nerve growth factor inducible
VN1R1 vomeronasal 1 receptor 1
ZAK sterile alpha motif and leucine zipper containing kinase AZK
ZCWPW1 zinc finger, CW type with PWWP domain 1
ZNF334 zinc finger protein 334
ZNF446 zinc finger protein 446
ZNF528 zinc finger protein 528
ZNF778 zinc finger protein 778
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