iodixanol-3023 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

194 genes differentially expressed following the iodixanol-3023 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABAT 4-aminobutyrate aminotransferase
ALDH1L1 aldehyde dehydrogenase 1 family, member L1
ANK2 ankyrin 2, neuronal
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26
ARTN artemin
ASPH aspartate beta-hydroxylase
BCL2L1 BCL2-like 1
C9ORF9 chromosome 9 open reading frame 9
CAPN5 calpain 5
CD58 CD58 molecule
CDH10 cadherin 10, type 2 (T2-cadherin)
CFP complement factor properdin
CHN2 chimerin 2
CHRNE cholinergic receptor, nicotinic, epsilon (muscle)
CKM creatine kinase, muscle
CNNM1 cyclin and CBS domain divalent metal cation transport mediator 1
COL14A1 collagen, type XIV, alpha 1
CYP39A1 cytochrome P450, family 39, subfamily A, polypeptide 1
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5
CYP4F2 cytochrome P450, family 4, subfamily F, polypeptide 2
DAPK2 death-associated protein kinase 2
DDAH2 dimethylarginine dimethylaminohydrolase 2
DGCR8 DGCR8 microprocessor complex subunit
DHX34 DEAH (Asp-Glu-Ala-His) box polypeptide 34
DNPEP aspartyl aminopeptidase
DPEP2 dipeptidase 2
EDN3 endothelin 3
EFS embryonal Fyn-associated substrate
EXOG endo/exonuclease (5'-3'), endonuclease G-like
EXT1 exostosin glycosyltransferase 1
FOXJ1 forkhead box J1
FXYD3 FXYD domain containing ion transport regulator 3
GJA8 gap junction protein, alpha 8, 50kDa
GLI2 GLI family zinc finger 2
GNMT glycine N-methyltransferase
GPR37L1 G protein-coupled receptor 37 like 1
GRM4 glutamate receptor, metabotropic 4
HOXB3 homeobox B3
HRG histidine-rich glycoprotein
HRH3 histamine receptor H3
HSF1 heat shock transcription factor 1
IGLV3-19 immunoglobulin lambda variable 3-19
KIAA1045 KIAA1045
KLF3 Kruppel-like factor 3 (basic)
LAMA4 laminin, alpha 4
LOC730101 uncharacterized LOC730101
MAPRE3 microtubule-associated protein, RP/EB family, member 3
MC2R melanocortin 2 receptor (adrenocorticotropic hormone)
MDK midkine (neurite growth-promoting factor 2)
MLF1 myeloid leukemia factor 1
MORC1 MORC family CW-type zinc finger 1
MRPL41 mitochondrial ribosomal protein L41
MRPS12 mitochondrial ribosomal protein S12
MTCP1 mature T-cell proliferation 1
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
NBR2 neighbor of BRCA1 gene 2 (non-protein coding)
NHLH2 nescient helix loop helix 2
NRAP nebulin-related anchoring protein
NTRK1 neurotrophic tyrosine kinase, receptor, type 1
OSBPL10 oxysterol binding protein-like 10
PALLD palladin, cytoskeletal associated protein
PAPPA pregnancy-associated plasma protein A, pappalysin 1
PCDHGA8 protocadherin gamma subfamily A, 8
PDX1 pancreatic and duodenal homeobox 1
PGAP3 post-GPI attachment to proteins 3
PIWIL1 piwi-like RNA-mediated gene silencing 1
POLR2L polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa
PPP2R5B protein phosphatase 2, regulatory subunit B', beta
QPCTL glutaminyl-peptide cyclotransferase-like
RGS14 regulator of G-protein signaling 14
RGS4 regulator of G-protein signaling 4
RHBG Rh family, B glycoprotein (gene/pseudogene)
RNF39 ring finger protein 39
RNF6 ring finger protein (C3H2C3 type) 6
RUNDC3A RUN domain containing 3A
SEMG2 semenogelin II
SLC22A1 solute carrier family 22 (organic cation transporter), member 1
SLC25A44 solute carrier family 25, member 44
SNTB2 syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)
SPDEF SAM pointed domain containing ETS transcription factor
ST8SIA1 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1
SVIL supervillin
TEAD3 TEA domain family member 3
TIAM1 T-cell lymphoma invasion and metastasis 1
TIMP3 TIMP metallopeptidase inhibitor 3
TOX thymocyte selection-associated high mobility group box
UGT2B4 UDP glucuronosyltransferase 2 family, polypeptide B4
VGLL1 vestigial-like family member 1
WISP3 WNT1 inducible signaling pathway protein 3
ZBTB7B zinc finger and BTB domain containing 7B
ZCCHC4 zinc finger, CCHC domain containing 4
ZFP36L2 ZFP36 ring finger protein-like 2
ZNF440 zinc finger protein 440
ZNF492 zinc finger protein 492
ZNF528 zinc finger protein 528
ZZEF1 zinc finger, ZZ-type with EF-hand domain 1

decreased expression

Symbol Name
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
ADAM15 ADAM metallopeptidase domain 15
AFF4 AF4/FMR2 family, member 4
ALDOAP2 aldolase A, fructose-bisphosphate pseudogene 2
ARMCX4 armadillo repeat containing, X-linked 4
C11ORF16 chromosome 11 open reading frame 16
C17ORF53 chromosome 17 open reading frame 53
C1ORF35 chromosome 1 open reading frame 35
C22ORF29 chromosome 22 open reading frame 29
C5AR1 complement component 5a receptor 1
C9ORF3 chromosome 9 open reading frame 3
CACNB4 calcium channel, voltage-dependent, beta 4 subunit
CCDC85C coiled-coil domain containing 85C
CD79B CD79b molecule, immunoglobulin-associated beta
CDK20 cyclin-dependent kinase 20
CHST4 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4
CISH cytokine inducible SH2-containing protein
CLCN5 chloride channel, voltage-sensitive 5
CTNNBIP1 catenin, beta interacting protein 1
CXORF56 chromosome X open reading frame 56
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
DCAF13 DDB1 and CUL4 associated factor 13
DDX43 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43
DOLK dolichol kinase
EDAR ectodysplasin A receptor
EXD3 exonuclease 3'-5' domain containing 3
EXOSC1 exosome component 1
FAM205BP transmembrane protein C9orf144B pseudogene
FAM46C family with sequence similarity 46, member C
FBXL7 F-box and leucine-rich repeat protein 7
FMOD fibromodulin
GAREM GRB2 associated, regulator of MAPK1
GATA4 GATA binding protein 4
GID4 GID complex subunit 4
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GPR35 G protein-coupled receptor 35
HIST1H3I histone cluster 1, H3i
HOXB9 homeobox B9
KCNK12 potassium channel, two pore domain subfamily K, member 12
KIAA0753 KIAA0753
LIN7B lin-7 homolog B (C. elegans)
LLPH LLP homolog, long-term synaptic facilitation (Aplysia)
LOC100286895 cell division cycle 27 homolog pseudogene
LOC57399 uncharacterized gastric protein ZA52P
LRRC20 leucine rich repeat containing 20
LTBP2 latent transforming growth factor beta binding protein 2
LY6D lymphocyte antigen 6 complex, locus D
MBTPS2 membrane-bound transcription factor peptidase, site 2
MMP9 matrix metallopeptidase 9
MYH4 myosin, heavy chain 4, skeletal muscle
NFE2L3 nuclear factor, erythroid 2-like 3
NOL10 nucleolar protein 10
OLFML2A olfactomedin-like 2A
PADI2 peptidyl arginine deiminase, type II
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PCDHGB6 protocadherin gamma subfamily B, 6
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
PLAT plasminogen activator, tissue
PPIP5K1 diphosphoinositol pentakisphosphate kinase 1
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit
PRKCZ protein kinase C, zeta
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
RNF126P1 ring finger protein 126 pseudogene 1
RPGR retinitis pigmentosa GTPase regulator
RWDD2A RWD domain containing 2A
S100A12 S100 calcium binding protein A12
SAA4 serum amyloid A4, constitutive
SCN5A sodium channel, voltage gated, type V alpha subunit
SETD1A SET domain containing 1A
SH2D4A SH2 domain containing 4A
SH3GLB2 SH3-domain GRB2-like endophilin B2
SIGLEC15 sialic acid binding Ig-like lectin 15
SLC35F6 solute carrier family 35, member F6
SNAI1 snail family zinc finger 1
SPINT1 serine peptidase inhibitor, Kunitz type 1
SPRR2B small proline-rich protein 2B
SRD5A2 steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2)
TAGLN3 transgelin 3
TBKBP1 TBK1 binding protein 1
TBR1 T-box, brain, 1
TGFBR1 transforming growth factor, beta receptor 1
TMEM140 transmembrane protein 140
TSPAN2 tetraspanin 2
TTPAL tocopherol (alpha) transfer protein-like
UPK2 uroplakin 2
USB1 U6 snRNA biogenesis 1
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
VPREB1 pre-B lymphocyte 1
XPNPEP3 X-prolyl aminopeptidase 3, mitochondrial
YPEL1 yippee-like 1 (Drosophila)
ZFHX3 zinc finger homeobox 3
ZNF254 zinc finger protein 254
ZNF415 zinc finger protein 415
ZNF76 zinc finger protein 76
ZNF81 zinc finger protein 81
ZNF816 zinc finger protein 816