iodixanol-3362 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the iodixanol-3362 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACOX2 acyl-CoA oxidase 2, branched chain
ADORA1 adenosine A1 receptor
APOD apolipoprotein D
ARHGAP26 Rho GTPase activating protein 26
ARHGAP44 Rho GTPase activating protein 44
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ARPIN actin-related protein 2/3 complex inhibitor
ATG3 autophagy related 3
BCAM basal cell adhesion molecule (Lutheran blood group)
CD2 CD2 molecule
CD3D CD3d molecule, delta (CD3-TCR complex)
CD70 CD70 molecule
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney)
CERS4 ceramide synthase 4
CFHR4 complement factor H-related 4
CFLAR CASP8 and FADD-like apoptosis regulator
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
COA1 cytochrome c oxidase assembly factor 1 homolog (S. cerevisiae)
COL11A2 collagen, type XI, alpha 2
CORT cortistatin
CRYBB2P1 crystallin, beta B2 pseudogene 1
DEF6 differentially expressed in FDCP 6 homolog (mouse)
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35
EDA ectodysplasin A
EPYC epiphycan
EXOSC1 exosome component 1
FABP3 fatty acid binding protein 3, muscle and heart
FAM198B family with sequence similarity 198, member B
FAM66D family with sequence similarity 66, member D
FKRP fukutin related protein
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
GABRG2 gamma-aminobutyric acid (GABA) A receptor, gamma 2
GABRG3 gamma-aminobutyric acid (GABA) A receptor, gamma 3
GDPD2 glycerophosphodiester phosphodiesterase domain containing 2
GPR135 G protein-coupled receptor 135
GPR182 G protein-coupled receptor 182
GRM6 glutamate receptor, metabotropic 6
GTF2A1 general transcription factor IIA, 1, 19/37kDa
HNRNPM heterogeneous nuclear ribonucleoprotein M
HOXA10 homeobox A10
HS3ST2 heparan sulfate (glucosamine) 3-O-sulfotransferase 2
IL1B interleukin 1, beta
ING1 inhibitor of growth family, member 1
IRS4 insulin receptor substrate 4
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
JUN jun proto-oncogene
KCNK10 potassium channel, two pore domain subfamily K, member 10
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KIAA1024 KIAA1024
KIR2DS1 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1
KRT20 keratin 20, type I
LIMK2 LIM domain kinase 2
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2
MKL1 megakaryoblastic leukemia (translocation) 1
MSR1 macrophage scavenger receptor 1
MST1L macrophage stimulating 1-like
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
MYCNOS MYCN opposite strand
NF1 neurofibromin 1
NPRL2 nitrogen permease regulator-like 2 (S. cerevisiae)
NUP188 nucleoporin 188kDa
OMG oligodendrocyte myelin glycoprotein
PDE10A phosphodiesterase 10A
PDHA2 pyruvate dehydrogenase (lipoamide) alpha 2
PICK1 protein interacting with PRKCA 1
PIP prolactin-induced protein
PKNOX1 PBX/knotted 1 homeobox 1
PLEKHS1 pleckstrin homology domain containing, family S member 1
PMEL premelanosome protein
PRB1 proline-rich protein BstNI subfamily 1
PRKCI protein kinase C, iota
PRSS53 protease, serine, 53
RAB6B RAB6B, member RAS oncogene family
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
RIMS2 regulating synaptic membrane exocytosis 2
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin)
RNF125 ring finger protein 125, E3 ubiquitin protein ligase
SAFB2 scaffold attachment factor B2
SAMD9 sterile alpha motif domain containing 9
SEMA7A semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group)
SFI1 Sfi1 homolog, spindle assembly associated (yeast)
SKAP1 src kinase associated phosphoprotein 1
SLC9A7 solute carrier family 9, subfamily A (NHE7, cation proton antiporter 7), member 7
SPAG8 sperm associated antigen 8
STAB2 stabilin 2
TAGLN3 transgelin 3
TET3 tet methylcytosine dioxygenase 3
TMEM176A transmembrane protein 176A
TNFRSF4 tumor necrosis factor receptor superfamily, member 4
TRIO trio Rho guanine nucleotide exchange factor
TSC22D2 TSC22 domain family, member 2
TTLL5 tubulin tyrosine ligase-like family member 5
WSB1 WD repeat and SOCS box containing 1
ZC3H7B zinc finger CCCH-type containing 7B
ZNF117 zinc finger protein 117
ZNF532 zinc finger protein 532
ZNF646 zinc finger protein 646
ZSCAN18 zinc finger and SCAN domain containing 18

decreased expression

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
ACTN4 actinin, alpha 4
APLP1 amyloid beta (A4) precursor-like protein 1
APOC4 apolipoprotein C-IV
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila)
B3GNT4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
BAHCC1 BAH domain and coiled-coil containing 1
BET1L Bet1 golgi vesicular membrane trafficking protein-like
C10ORF95 chromosome 10 open reading frame 95
C17ORF53 chromosome 17 open reading frame 53
C1ORF56 chromosome 1 open reading frame 56
C6ORF47 chromosome 6 open reading frame 47
C7ORF43 chromosome 7 open reading frame 43
CAMK1 calcium/calmodulin-dependent protein kinase I
CBX7 chromobox homolog 7
CCDC121 coiled-coil domain containing 121
CCDC71 coiled-coil domain containing 71
CGA glycoprotein hormones, alpha polypeptide
CRTAP cartilage associated protein
CYP4F12 cytochrome P450, family 4, subfamily F, polypeptide 12
DCBLD2 discoidin, CUB and LCCL domain containing 2
DGAT1 diacylglycerol O-acyltransferase 1
DNAJC24 DnaJ (Hsp40) homolog, subfamily C, member 24
DYSF dysferlin
ENO3 enolase 3 (beta, muscle)
ERN2 endoplasmic reticulum to nucleus signaling 2
FAM188A family with sequence similarity 188, member A
FAN1 FANCD2/FANCI-associated nuclease 1
FBXL2 F-box and leucine-rich repeat protein 2
FBXO2 F-box protein 2
FSCN1 fascin actin-bundling protein 1
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
GEMIN8 gem (nuclear organelle) associated protein 8
GFI1 growth factor independent 1 transcription repressor
GK3P glycerol kinase 3 pseudogene
GPR157 G protein-coupled receptor 157
GRAMD1C GRAM domain containing 1C
HMOX1 heme oxygenase 1
HOXA4 homeobox A4
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
INO80D INO80 complex subunit D
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KIAA0355 KIAA0355
KIAA1107 KIAA1107
LHX1 LIM homeobox 1
LOC257152 uncharacterized LOC257152
MALL mal, T-cell differentiation protein-like
MAP3K8 mitogen-activated protein kinase kinase kinase 8
MEIS2 Meis homeobox 2
MINOS1P1 mitochondrial inner membrane organizing system 1 pseudogene 1
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
MTA2 metastasis associated 1 family, member 2
MTMR6 myotubularin related protein 6
MYOZ3 myozenin 3
N4BP3 NEDD4 binding protein 3
NDRG4 NDRG family member 4
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon
NIPAL2 NIPA-like domain containing 2
NPM3 nucleophosmin/nucleoplasmin 3
PDE12 phosphodiesterase 12
PEX26 peroxisomal biogenesis factor 26
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PLCD1 phospholipase C, delta 1
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PMCH pro-melanin-concentrating hormone
POM121 POM121 transmembrane nucleoporin
PPP2R3B protein phosphatase 2, regulatory subunit B'', beta
RAB3A RAB3A, member RAS oncogene family
RNF121 ring finger protein 121
RPUSD2 RNA pseudouridylate synthase domain containing 2
SALL2 spalt-like transcription factor 2
SAYSD1 SAYSVFN motif domain containing 1
SFT2D2 SFT2 domain containing 2
SGCG sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)
SH3TC1 SH3 domain and tetratricopeptide repeats 1
SLC22A18AS solute carrier family 22 (organic cation transporter), member 18 antisense
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1
SOX3 SRY (sex determining region Y)-box 3
STARD3 StAR-related lipid transfer (START) domain containing 3
SYNC syncoilin, intermediate filament protein
TCHH trichohyalin
TCTN2 tectonic family member 2
TH tyrosine hydroxylase
THNSL2 threonine synthase-like 2 (S. cerevisiae)
TM6SF1 transmembrane 6 superfamily member 1
TMEM212 transmembrane protein 212
TONSL tonsoku-like, DNA repair protein
TPK1 thiamin pyrophosphokinase 1
UPP1 uridine phosphorylase 1
USB1 U6 snRNA biogenesis 1
VLDLR very low density lipoprotein receptor
WDR62 WD repeat domain 62
ZFHX2 zinc finger homeobox 2
ZNF227 zinc finger protein 227
ZNF34 zinc finger protein 34
ZNF358 zinc finger protein 358
ZNF432 zinc finger protein 432
ZNF770 zinc finger protein 770