| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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196 genes differentially expressed following the iohexol-2461 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AHDC1 | AT hook, DNA binding motif, containing 1 |
| ANKMY1 | ankyrin repeat and MYND domain containing 1 |
| ANKRD7 | ankyrin repeat domain 7 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit |
| ARHGAP6 | Rho GTPase activating protein 6 |
| ARSD | arylsulfatase D |
| ATXN2L | ataxin 2-like |
| C20ORF27 | chromosome 20 open reading frame 27 |
| CA1 | carbonic anhydrase I |
| CA9 | carbonic anhydrase IX |
| CACNB3 | calcium channel, voltage-dependent, beta 3 subunit |
| CALML3 | calmodulin-like 3 |
| CARD10 | caspase recruitment domain family, member 10 |
| CD47 | CD47 molecule |
| CDH1 | cadherin 1, type 1, E-cadherin (epithelial) |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 |
| CFLAR | CASP8 and FADD-like apoptosis regulator |
| CGA | glycoprotein hormones, alpha polypeptide |
| CORO1B | coronin, actin binding protein, 1B |
| CPTP | ceramide-1-phosphate transfer protein |
| CRHR1 | corticotropin releasing hormone receptor 1 |
| CSHL1 | chorionic somatomammotropin hormone-like 1 |
| DEFA4 | defensin, alpha 4, corticostatin |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 |
| DNAJC6 | DnaJ (Hsp40) homolog, subfamily C, member 6 |
| EN1 | engrailed homeobox 1 |
| FADS3 | fatty acid desaturase 3 |
| FAM3A | family with sequence similarity 3, member A |
| FBXL18 | F-box and leucine-rich repeat protein 18 |
| FCAR | Fc fragment of IgA receptor |
| FCMR | Fc fragment of IgM receptor |
| FLT3LG | fms-related tyrosine kinase 3 ligand |
| GYG2 | glycogenin 2 |
| HDLBP | high density lipoprotein binding protein |
| HIST1H2AL | histone cluster 1, H2al |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase |
| IZUMO4 | IZUMO family member 4 |
| KCNE2 | potassium channel, voltage gated subfamily E regulatory beta subunit 2 |
| KCNN1 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1 |
| KLF3 | Kruppel-like factor 3 (basic) |
| LDHC | lactate dehydrogenase C |
| LIMCH1 | LIM and calponin homology domains 1 |
| LMOD1 | leiomodin 1 (smooth muscle) |
| LPAR1 | lysophosphatidic acid receptor 1 |
| LPP | LIM domain containing preferred translocation partner in lipoma |
| LY6G6C | lymphocyte antigen 6 complex, locus G6C |
| MAP3K6 | mitogen-activated protein kinase kinase kinase 6 |
| MBL1P | mannose-binding lectin (protein A) 1, pseudogene |
| MMP16 | matrix metallopeptidase 16 (membrane-inserted) |
| MYO1B | myosin IB |
| MYO6 | myosin VI |
| NECAB3 | N-terminal EF-hand calcium binding protein 3 |
| NEUROD1 | neuronal differentiation 1 |
| NPM3 | nucleophosmin/nucleoplasmin 3 |
| NRCAM | neuronal cell adhesion molecule |
| OASL | 2'-5'-oligoadenylate synthetase-like |
| OR1D2 | olfactory receptor, family 1, subfamily D, member 2 |
| P2RY4 | pyrimidinergic receptor P2Y, G-protein coupled, 4 |
| P2RY6 | pyrimidinergic receptor P2Y, G-protein coupled, 6 |
| PAPSS2 | 3'-phosphoadenosine 5'-phosphosulfate synthase 2 |
| PBX2 | pre-B-cell leukemia homeobox 2 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) |
| PKP3 | plakophilin 3 |
| PNMAL1 | paraneoplastic Ma antigen family-like 1 |
| PPP1R26 | protein phosphatase 1, regulatory subunit 26 |
| PSG11 | pregnancy specific beta-1-glycoprotein 11 |
| PTTG2 | pituitary tumor-transforming 2 |
| RAB5C | RAB5C, member RAS oncogene family |
| RAC3 | ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) |
| RBM5 | RNA binding motif protein 5 |
| REPS1 | RALBP1 associated Eps domain containing 1 |
| RPGRIP1L | RPGRIP1-like |
| RPL10L | ribosomal protein L10-like |
| RUNX1 | runt-related transcription factor 1 |
| SH3BP1 | SH3-domain binding protein 1 |
| SH3BP2 | SH3-domain binding protein 2 |
| SH3PXD2A | SH3 and PX domains 2A |
| SIGLEC8 | sialic acid binding Ig-like lectin 8 |
| SLC12A4 | solute carrier family 12 (potassium/chloride transporter), member 4 |
| SLC13A1 | solute carrier family 13 (sodium/sulfate symporter), member 1 |
| SLC22A5 | solute carrier family 22 (organic cation/carnitine transporter), member 5 |
| SLC35E2 | solute carrier family 35, member E2 |
| SRCAP | Snf2-related CREBBP activator protein |
| ST8SIA3 | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3 |
| STK3 | serine/threonine kinase 3 |
| SYDE1 | synapse defective 1, Rho GTPase, homolog 1 (C. elegans) |
| TBX10 | T-box 10 |
| TFF2 | trefoil factor 2 |
| TMEM140 | transmembrane protein 140 |
| TMEM212 | transmembrane protein 212 |
| TRGV5 | T cell receptor gamma variable 5 |
| VAMP2 | vesicle-associated membrane protein 2 (synaptobrevin 2) |
| WAS | Wiskott-Aldrich syndrome |
| WDR25 | WD repeat domain 25 |
| ZBTB22 | zinc finger and BTB domain containing 22 |
| ZC3H7B | zinc finger CCCH-type containing 7B |
| ZFHX2 | zinc finger homeobox 2 |
| ZNF124 | zinc finger protein 124 |
| Symbol | Name |
|---|---|
| ACTR8 | ARP8 actin-related protein 8 homolog (yeast) |
| ANP32A-IT1 | ANP32A intronic transcript 1 |
| APOO | apolipoprotein O |
| BANK1 | B-cell scaffold protein with ankyrin repeats 1 |
| BAX | BCL2-associated X protein |
| BTK | Bruton agammaglobulinemia tyrosine kinase |
| C4ORF29 | chromosome 4 open reading frame 29 |
| C8ORF44 | chromosome 8 open reading frame 44 |
| C8ORF60 | chromosome 8 open reading frame 60 |
| CBL | Cbl proto-oncogene, E3 ubiquitin protein ligase |
| CDK6 | cyclin-dependent kinase 6 |
| CDR2L | cerebellar degeneration-related protein 2-like |
| CEP295 | centrosomal protein 295kDa |
| CES3 | carboxylesterase 3 |
| CHRNA5 | cholinergic receptor, nicotinic, alpha 5 (neuronal) |
| CPPED1 | calcineurin-like phosphoesterase domain containing 1 |
| CXCR2 | chemokine (C-X-C motif) receptor 2 |
| DBF4B | DBF4 zinc finger B |
| DHRS11 | dehydrogenase/reductase (SDR family) member 11 |
| DHX38 | DEAH (Asp-Glu-Ala-His) box polypeptide 38 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| FADD | Fas (TNFRSF6)-associated via death domain |
| FLCN | folliculin |
| GANAB | glucosidase, alpha; neutral AB |
| GAR1 | GAR1 ribonucleoprotein |
| GATC | glutamyl-tRNA(Gln) amidotransferase, subunit C |
| GINS4 | GINS complex subunit 4 (Sld5 homolog) |
| GSTCD | glutathione S-transferase, C-terminal domain containing |
| GTF2H3 | general transcription factor IIH, polypeptide 3, 34kDa |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HACD3 | 3-hydroxyacyl-CoA dehydratase 3 |
| HELLS | helicase, lymphoid-specific |
| HIRA | histone cell cycle regulator |
| HIST1H1E | histone cluster 1, H1e |
| KLHL28 | kelch-like family member 28 |
| LOC100287590 | uncharacterized LOC100287590 |
| LRP5 | low density lipoprotein receptor-related protein 5 |
| LRRC37A3 | leucine rich repeat containing 37, member A3 |
| LZTS3 | leucine zipper, putative tumor suppressor family member 3 |
| MBTD1 | mbt domain containing 1 |
| MBTPS2 | membrane-bound transcription factor peptidase, site 2 |
| MED18 | mediator complex subunit 18 |
| MEGF8 | multiple EGF-like-domains 8 |
| METTL2B | methyltransferase like 2B |
| METTL8 | methyltransferase like 8 |
| MIR22HG | MIR22 host gene |
| MPHOSPH8 | M-phase phosphoprotein 8 |
| MYBBP1A | MYB binding protein (P160) 1a |
| NAA15 | N(alpha)-acetyltransferase 15, NatA auxiliary subunit |
| NCAPG2 | non-SMC condensin II complex, subunit G2 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
| NFE2L3 | nuclear factor, erythroid 2-like 3 |
| OR7E47P | olfactory receptor, family 7, subfamily E, member 47 pseudogene |
| PLEKHA2 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2 |
| PMVK | phosphomevalonate kinase |
| PNOC | prepronociceptin |
| POLR2J2 | polymerase (RNA) II (DNA directed) polypeptide J2 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor |
| PPM1E | protein phosphatase, Mg2+/Mn2+ dependent, 1E |
| PRKAG1 | protein kinase, AMP-activated, gamma 1 non-catalytic subunit |
| PRRG4 | proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) |
| R3HCC1L | R3H domain and coiled-coil containing 1-like |
| RCAN3 | RCAN family member 3 |
| RFXAP | regulatory factor X-associated protein |
| RNF122 | ring finger protein 122 |
| RNF125 | ring finger protein 125, E3 ubiquitin protein ligase |
| RNFT1 | ring finger protein, transmembrane 1 |
| RPP14 | ribonuclease P/MRP 14kDa subunit |
| SDF2L1 | stromal cell-derived factor 2-like 1 |
| SH2D3C | SH2 domain containing 3C |
| SNAPC2 | small nuclear RNA activating complex, polypeptide 2, 45kDa |
| STAG3L1 | stromal antigen 3-like 1 (pseudogene) |
| STK16 | serine/threonine kinase 16 |
| STK19 | serine/threonine kinase 19 |
| STX11 | syntaxin 11 |
| SUZ12P1 | suppressor of zeste 12 homolog pseudogene 1 |
| TEP1 | telomerase-associated protein 1 |
| TIMM50 | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) |
| TPM4 | tropomyosin 4 |
| TPST1 | tyrosylprotein sulfotransferase 1 |
| TRMT2B | tRNA methyltransferase 2 homolog B (S. cerevisiae) |
| U2AF1 | U2 small nuclear RNA auxiliary factor 1 |
| VNN2 | vanin 2 |
| WDR62 | WD repeat domain 62 |
| XPNPEP3 | X-prolyl aminopeptidase 3, mitochondrial |
| XRCC2 | X-ray repair complementing defective repair in Chinese hamster cells 2 |
| ZC4H2 | zinc finger, C4H2 domain containing |
| ZFYVE21 | zinc finger, FYVE domain containing 21 |
| ZNF160 | zinc finger protein 160 |
| ZNF264 | zinc finger protein 264 |
| ZNF345 | zinc finger protein 345 |
| ZNF426 | zinc finger protein 426 |
| ZNF652 | zinc finger protein 652 |
| ZNF654 | zinc finger protein 654 |
| ZNF721 | zinc finger protein 721 |
| ZNF768 | zinc finger protein 768 |
| ZW10 | zw10 kinetochore protein |