iohexol-3322 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

193 genes differentially expressed following the iohexol-3322 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAM12 ADAM metallopeptidase domain 12
AHI1 Abelson helper integration site 1
AKAP7 A kinase (PRKA) anchor protein 7
ALMS1 Alstrom syndrome protein 1
AMBRA1 autophagy/beclin-1 regulator 1
ARHGAP44 Rho GTPase activating protein 44
ATXN2L ataxin 2-like
BAHD1 bromo adjacent homology domain containing 1
BCAM basal cell adhesion molecule (Lutheran blood group)
C17ORF53 chromosome 17 open reading frame 53
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CAPN15 calpain 15
CCL19 chemokine (C-C motif) ligand 19
CD8A CD8a molecule
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3
CELSR3 cadherin, EGF LAG seven-pass G-type receptor 3
CNPPD1 cyclin Pas1/PHO80 domain containing 1
CORO7 coronin 7
CSF1 colony stimulating factor 1 (macrophage)
CTIF CBP80/20-dependent translation initiation factor
CXADR coxsackie virus and adenovirus receptor
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DRD2 dopamine receptor D2
DSCAM Down syndrome cell adhesion molecule
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
ELOVL5 ELOVL fatty acid elongase 5
EVPL envoplakin
F3 coagulation factor III (thromboplastin, tissue factor)
FAM102A family with sequence similarity 102, member A
FHOD1 formin homology 2 domain containing 1
FLJ22184
FOSL2 FOS-like antigen 2
FOXN3 forkhead box N3
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GLB1L galactosidase, beta 1-like
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GPR137 G protein-coupled receptor 137
GRIK5 glutamate receptor, ionotropic, kainate 5
GUSBP3 glucuronidase, beta pseudogene 3
HDAC5 histone deacetylase 5
HDAC7 histone deacetylase 7
HIST1H1D histone cluster 1, H1d
HIST1H4F histone cluster 1, H4f
HOXC4 homeobox C4
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker)
IQSEC1 IQ motif and Sec7 domain 1
KIF1C kinesin family member 1C
KLHL22 kelch-like family member 22
KRT24 keratin 24, type I
LGALS9 lectin, galactoside-binding, soluble, 9
LIMK1 LIM domain kinase 1
LRCH4 leucine-rich repeats and calponin homology (CH) domain containing 4
MAN1A2 mannosidase, alpha, class 1A, member 2
MED16 mediator complex subunit 16
MMP15 matrix metallopeptidase 15 (membrane-inserted)
MNMIP1 manchette microtubule inner protein 1
MORN1 MORN repeat containing 1
MRPS12 mitochondrial ribosomal protein S12
MZF1 myeloid zinc finger 1
NOVA2 neuro-oncological ventral antigen 2
NR2F1 nuclear receptor subfamily 2, group F, member 1
NR4A1 nuclear receptor subfamily 4, group A, member 1
PDLIM5 PDZ and LIM domain 5
PDLIM7 PDZ and LIM domain 7 (enigma)
PER3 period circadian clock 3
PGLYRP4 peptidoglycan recognition protein 4
PHACTR4 phosphatase and actin regulator 4
PLTP phospholipid transfer protein
POU2F2 POU class 2 homeobox 2
PPP2R5B protein phosphatase 2, regulatory subunit B', beta
PRB1 proline-rich protein BstNI subfamily 1
PTGDS prostaglandin D2 synthase 21kDa (brain)
PTK6 protein tyrosine kinase 6
PTN pleiotrophin
RAD54L2 RAD54-like 2 (S. cerevisiae)
RANBP10 RAN binding protein 10
RPL13P5 ribosomal protein L13 pseudogene 5
RPS4Y1 ribosomal protein S4, Y-linked 1
S100A8 S100 calcium binding protein A8
SLC6A20 solute carrier family 6 (proline IMINO transporter), member 20
SLC9A5 solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5
SUPT6H suppressor of Ty 6 homolog (S. cerevisiae)
TAOK1 TAO kinase 1
TNPO2 transportin 2
TSC22D4 TSC22 domain family, member 4
TSPAN2 tetraspanin 2
UBXN1 UBX domain protein 1
VASH1 vasohibin 1
VPS13D vacuolar protein sorting 13 homolog D (S. cerevisiae)
ZCCHC14 zinc finger, CCHC domain containing 14
ZFP36L2 ZFP36 ring finger protein-like 2
ZMIZ2 zinc finger, MIZ-type containing 2
ZNF235 zinc finger protein 235
ZNF592 zinc finger protein 592

decreased expression

Symbol Name
ABHD17B abhydrolase domain containing 17B
AHSP alpha hemoglobin stabilizing protein
ALPK1 alpha-kinase 1
ARHGAP4 Rho GTPase activating protein 4
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16
ATAT1 alpha tubulin acetyltransferase 1
ATG16L1 autophagy related 16-like 1 (S. cerevisiae)
B3GNT4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
BMP10 bone morphogenetic protein 10
C11ORF21 chromosome 11 open reading frame 21
C17ORF80 chromosome 17 open reading frame 80
C19ORF73 chromosome 19 open reading frame 73
C8ORF44 chromosome 8 open reading frame 44
CA11 carbonic anhydrase XI
CA5BP1 carbonic anhydrase VB pseudogene 1
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CCDC64 coiled-coil domain containing 64
CDK3 cyclin-dependent kinase 3
CEP72 centrosomal protein 72kDa
CHML choroideremia-like (Rab escort protein 2)
CHRNA6 cholinergic receptor, nicotinic, alpha 6 (neuronal)
CLEC4E C-type lectin domain family 4, member E
COPZ2 coatomer protein complex, subunit zeta 2
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
CYP4F11 cytochrome P450, family 4, subfamily F, polypeptide 11
DNAJC7 DnaJ (Hsp40) homolog, subfamily C, member 7
EFNA3 ephrin-A3
EGLN3 egl-9 family hypoxia-inducible factor 3
EHMT1 euchromatic histone-lysine N-methyltransferase 1
EMCN endomucin
EPB41L5 erythrocyte membrane protein band 4.1 like 5
ERCC4 excision repair cross-complementation group 4
FAM188A family with sequence similarity 188, member A
FBXL7 F-box and leucine-rich repeat protein 7
FBXL8 F-box and leucine-rich repeat protein 8
FBXO22 F-box protein 22
FER fer (fps/fes related) tyrosine kinase
FKBP5 FK506 binding protein 5
GADD45G growth arrest and DNA-damage-inducible, gamma
GDAP1 ganglioside induced differentiation associated protein 1
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GPATCH2L G patch domain containing 2-like
GPR176 G protein-coupled receptor 176
HCN4 hyperpolarization activated cyclic nucleotide gated potassium channel 4
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HPN hepsin
HSD17B14 hydroxysteroid (17-beta) dehydrogenase 14
IKZF5 IKAROS family zinc finger 5 (Pegasus)
KCTD20 potassium channel tetramerization domain containing 20
KIAA0319L KIAA0319-like
KIFAP3 kinesin-associated protein 3
KITLG KIT ligand
KLHL28 kelch-like family member 28
KLK8 kallikrein-related peptidase 8
KLRG1 killer cell lectin-like receptor subfamily G, member 1
LAS1L LAS1-like (S. cerevisiae)
METTL16 methyltransferase like 16
MGC12488
MMP3 matrix metallopeptidase 3
MSI1 musashi RNA-binding protein 1
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NMD3 NMD3 ribosome export adaptor
NPTX1 neuronal pentraxin I
NSUN6 NOP2/Sun domain family, member 6
PDIA3 protein disulfide isomerase family A, member 3
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PGBD5 piggyBac transposable element derived 5
PIGH phosphatidylinositol glycan anchor biosynthesis, class H
PLEKHA2 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2
PTPRS protein tyrosine phosphatase, receptor type, S
RAB30 RAB30, member RAS oncogene family
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
RELN reelin
RNF141 ring finger protein 141
SAYSD1 SAYSVFN motif domain containing 1
SCN1B sodium channel, voltage gated, type I beta subunit
SCRN3 secernin 3
SH2D4A SH2 domain containing 4A
SLC12A6 solute carrier family 12 (potassium/chloride transporter), member 6
SLC7A2 solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
STX1A syntaxin 1A (brain)
TLR2 toll-like receptor 2
TLR5 toll-like receptor 5
TPSG1 tryptase gamma 1
TRNAU1AP tRNA selenocysteine 1 associated protein 1
UCN urocortin
VGF VGF nerve growth factor inducible
WARS2 tryptophanyl tRNA synthetase 2, mitochondrial
WDR91 WD repeat domain 91
YY2 YY2 transcription factor
ZIC3 Zic family member 3
ZNF205 zinc finger protein 205
ZNF493 zinc finger protein 493
ZNF639 zinc finger protein 639
ZNF665 zinc finger protein 665
ZNF747 zinc finger protein 747