iohexol-4643 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

194 genes differentially expressed following the iohexol-4643 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACTG2 actin, gamma 2, smooth muscle, enteric
ADCY6 adenylate cyclase 6
ADD2 adducin 2 (beta)
ADRBK1 adrenergic, beta, receptor kinase 1
ANKRD6 ankyrin repeat domain 6
AP2A2 adaptor-related protein complex 2, alpha 2 subunit
ARHGAP33 Rho GTPase activating protein 33
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2
ARRB2 arrestin, beta 2
ASTN2 astrotactin 2
BCL6 B-cell CLL/lymphoma 6
BEX1 brain expressed, X-linked 1
BGLAP bone gamma-carboxyglutamate (gla) protein
BNC1 basonuclin 1
C1ORF116 chromosome 1 open reading frame 116
CA5B carbonic anhydrase VB, mitochondrial
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CCDC170 coiled-coil domain containing 170
CCNJL cyclin J-like
CDC25C cell division cycle 25C
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1
CHM choroideremia (Rab escort protein 1)
CLTCL1 clathrin, heavy chain-like 1
CPM carboxypeptidase M
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1)
DDX11 DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11
DGKA diacylglycerol kinase, alpha 80kDa
DOCK6 dedicator of cytokinesis 6
DST dystonin
EGR2 early growth response 2
EML3 echinoderm microtubule associated protein like 3
FAIM2 Fas apoptotic inhibitory molecule 2
FAM105A family with sequence similarity 105, member A
FAM63A family with sequence similarity 63, member A
FLJ11292
FUZ fuzzy planar cell polarity protein
GIPR gastric inhibitory polypeptide receptor
GMEB1 glucocorticoid modulatory element binding protein 1
GREM1 gremlin 1, DAN family BMP antagonist
HIST1H4F histone cluster 1, H4f
HLA-DMA major histocompatibility complex, class II, DM alpha
ICAM1 intercellular adhesion molecule 1
ICOSLG inducible T-cell co-stimulator ligand
INPP5J inositol polyphosphate-5-phosphatase J
KCNK12 potassium channel, two pore domain subfamily K, member 12
KLRG1 killer cell lectin-like receptor subfamily G, member 1
LTBP4 latent transforming growth factor beta binding protein 4
MANBA mannosidase, beta A, lysosomal
MAPRE3 microtubule-associated protein, RP/EB family, member 3
MST1 macrophage stimulating 1
NF2 neurofibromin 2 (merlin)
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
PAX8 paired box 8
PDE4C phosphodiesterase 4C, cAMP-specific
PDE4DIP phosphodiesterase 4D interacting protein
PHF20L1 PHD finger protein 20-like 1
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PKLR pyruvate kinase, liver and RBC
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PLCD1 phospholipase C, delta 1
PTPRU protein tyrosine phosphatase, receptor type, U
R3HCC1L R3H domain and coiled-coil containing 1-like
RAB28 RAB28, member RAS oncogene family
RALB v-ral simian leukemia viral oncogene homolog B
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
RC3H2 ring finger and CCCH-type domains 2
RDH11 retinol dehydrogenase 11 (all-trans/9-cis/11-cis)
RGS5 regulator of G-protein signaling 5
RGS6 regulator of G-protein signaling 6
RPH3AL rabphilin 3A-like (without C2 domains)
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
SEMA7A semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group)
SENP3 SUMO1/sentrin/SMT3 specific peptidase 3
SHOX2 short stature homeobox 2
SLC17A2 solute carrier family 17, member 2
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SPANXC SPANX family, member C
SYCP2 synaptonemal complex protein 2
TAGLN3 transgelin 3
TAPBP TAP binding protein (tapasin)
TCF4 transcription factor 4
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TNIK TRAF2 and NCK interacting kinase
TOP3A topoisomerase (DNA) III alpha
TPP1 tripeptidyl peptidase I
TRAFD1 TRAF-type zinc finger domain containing 1
TRAPPC13 trafficking protein particle complex 13
VCAN versican
VPS41 vacuolar protein sorting 41 homolog (S. cerevisiae)
XYLB xylulokinase homolog (H. influenzae)
ZHX3 zinc fingers and homeoboxes 3
ZNF268 zinc finger protein 268
ZNF467 zinc finger protein 467
ZNF589 zinc finger protein 589
ZNF76 zinc finger protein 76

decreased expression

Symbol Name
ACOXL acyl-CoA oxidase-like
AGO4 argonaute RISC catalytic component 4
AIM2 absent in melanoma 2
AKR1C4 aldo-keto reductase family 1, member C4
AMH anti-Mullerian hormone
ANKRD2 ankyrin repeat domain 2 (stretch responsive muscle)
APOBEC3F apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3F
APOL6 apolipoprotein L, 6
BAIAP3 BAI1-associated protein 3
C5ORF45 chromosome 5 open reading frame 45
C7ORF69 chromosome 7 open reading frame 69
CASP5 caspase 5, apoptosis-related cysteine peptidase
CCDC106 coiled-coil domain containing 106
CDH10 cadherin 10, type 2 (T2-cadherin)
CELP carboxyl ester lipase pseudogene
CGA glycoprotein hormones, alpha polypeptide
CISH cytokine inducible SH2-containing protein
COL9A3 collagen, type IX, alpha 3
CRYGC crystallin, gamma C
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
CYP4F11 cytochrome P450, family 4, subfamily F, polypeptide 11
DDN dendrin
EDN1 endothelin 1
EYA3 EYA transcriptional coactivator and phosphatase 3
FAM13C family with sequence similarity 13, member C
FBRS fibrosin
FMO4 flavin containing monooxygenase 4
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group)
GABARAPL3 GABA(A) receptors associated protein like 3, pseudogene
GADD45G growth arrest and DNA-damage-inducible, gamma
GPR37L1 G protein-coupled receptor 37 like 1
GSTA3 glutathione S-transferase alpha 3
HAMP hepcidin antimicrobial peptide
HEYL hes-related family bHLH transcription factor with YRPW motif-like
HIST1H1T histone cluster 1, H1t
HIST1H2BO histone cluster 1, H2bo
HIST2H2AA3 histone cluster 2, H2aa3
HOXA7 homeobox A7
HOXD11 homeobox D11
HRH2 histamine receptor H2
HSPB6 heat shock protein, alpha-crystallin-related, B6
IFT140 intraflagellar transport 140
IGLL3P immunoglobulin lambda-like polypeptide 3, pseudogene
IL15RA interleukin 15 receptor, alpha
IL32 interleukin 32
IL36RN interleukin 36 receptor antagonist
IRF2BP1 interferon regulatory factor 2 binding protein 1
ITK IL2-inducible T-cell kinase
KCNA5 potassium channel, voltage gated shaker related subfamily A, member 5
KLF3 Kruppel-like factor 3 (basic)
KRT31 keratin 31, type I
KRTAP1-3 keratin associated protein 1-3
LBX1 ladybird homeobox 1
LIMS2 LIM and senescent cell antigen-like domains 2
LOC100129648 uncharacterized LOC100129648
MAFK v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K
MRPL41 mitochondrial ribosomal protein L41
MTSS1L metastasis suppressor 1-like
MYH15 myosin, heavy chain 15
NAALAD2 N-acetylated alpha-linked acidic dipeptidase 2
NAT6 N-acetyltransferase 6 (GCN5-related)
NEUROD1 neuronal differentiation 1
NPIPB15 nuclear pore complex interacting protein family, member B15
NT5M 5',3'-nucleotidase, mitochondrial
OLFM4 olfactomedin 4
OR1G1 olfactory receptor, family 1, subfamily G, member 1
PBOV1 prostate and breast cancer overexpressed 1
PCDHB13 protocadherin beta 13
PDE8B phosphodiesterase 8B
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
POLL polymerase (DNA directed), lambda
PTTG2 pituitary tumor-transforming 2
RAPSN receptor-associated protein of the synapse
RBM12B-AS1 RBM12B antisense RNA 1
RFPL1S RFPL1 antisense RNA 1
RGR retinal G protein coupled receptor
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
SCGB2A2 secretoglobin, family 2A, member 2
SCN1B sodium channel, voltage gated, type I beta subunit
SETD8 SET domain containing (lysine methyltransferase) 8
SLC16A6 solute carrier family 16, member 6
STAG3 stromal antigen 3
STAG3L4 stromal antigen 3-like 4 (pseudogene)
TCEAL2 transcription elongation factor A (SII)-like 2
TMEM159 transmembrane protein 159
TNFRSF17 tumor necrosis factor receptor superfamily, member 17
TSNAXIP1 translin-associated factor X interacting protein 1
TSPAN2 tetraspanin 2
USP20 ubiquitin specific peptidase 20
WDR78 WD repeat domain 78
WFDC2 WAP four-disulfide core domain 2
XYLT2 xylosyltransferase II
ZNF10 zinc finger protein 10
ZNF141 zinc finger protein 141
ZNF208 zinc finger protein 208
ZNF222 zinc finger protein 222
ZSCAN2 zinc finger and SCAN domain containing 2