iohexol-5704 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the iohexol-5704 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACOXL acyl-CoA oxidase-like
ADAM5 ADAM metallopeptidase domain 5 (pseudogene)
ADAMTS9 ADAM metallopeptidase with thrombospondin type 1 motif, 9
AFF2 AF4/FMR2 family, member 2
AQP3 aquaporin 3 (Gill blood group)
ATP9B ATPase, class II, type 9B
BAZ1B bromodomain adjacent to zinc finger domain, 1B
BEGAIN brain-enriched guanylate kinase-associated
BEST2 bestrophin 2
C19ORF66 chromosome 19 open reading frame 66
C8ORF17 chromosome 8 open reading frame 17
CALB2 calbindin 2
CAMK2B calcium/calmodulin-dependent protein kinase II beta
CCL27 chemokine (C-C motif) ligand 27
CD3D CD3d molecule, delta (CD3-TCR complex)
CDC14B cell division cycle 14B
CLCN4 chloride channel, voltage-sensitive 4
CLDN15 claudin 15
CLEC5A C-type lectin domain family 5, member A
COL11A1 collagen, type XI, alpha 1
CYLD cylindromatosis (turban tumor syndrome)
DNAJC4 DnaJ (Hsp40) homolog, subfamily C, member 4
EFNB3 ephrin-B3
FAM49B family with sequence similarity 49, member B
FGF18 fibroblast growth factor 18
FGL1 fibrinogen-like 1
FLJ11292
GABRA1 gamma-aminobutyric acid (GABA) A receptor, alpha 1
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2
GPR153 G protein-coupled receptor 153
GRIP2 glutamate receptor interacting protein 2
HIC2 hypermethylated in cancer 2
HNRNPM heterogeneous nuclear ribonucleoprotein M
IGLJ3 immunoglobulin lambda joining 3
IL11 interleukin 11
IL11RA interleukin 11 receptor, alpha
IMPG2 interphotoreceptor matrix proteoglycan 2
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KIAA0125 KIAA0125
KIR2DS1 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1
LAT2 linker for activation of T cells family, member 2
LOC100131510 uncharacterized LOC100131510
LUZP1 leucine zipper protein 1
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2
MECOM MDS1 and EVI1 complex locus
MMP13 matrix metallopeptidase 13
MOGAT2 monoacylglycerol O-acyltransferase 2
MSH6 mutS homolog 6
MUC3A mucin 3A, cell surface associated
MYT1L myelin transcription factor 1-like
NEUROD4 neuronal differentiation 4
NMT1 N-myristoyltransferase 1
NOD2 nucleotide-binding oligomerization domain containing 2
NOTCH2 notch 2
NPHS2 nephrosis 2, idiopathic, steroid-resistant (podocin)
OR10H1 olfactory receptor, family 10, subfamily H, member 1
OVOL1 ovo-like zinc finger 1
P2RX2 purinergic receptor P2X, ligand gated ion channel, 2
PAPPA2 pappalysin 2
PARD3 par-3 family cell polarity regulator
PHOX2A paired-like homeobox 2a
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PLCD1 phospholipase C, delta 1
PRSS3 protease, serine, 3
PSD3 pleckstrin and Sec7 domain containing 3
RAB3A RAB3A, member RAS oncogene family
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
RGS12 regulator of G-protein signaling 12
RSPH14 radial spoke head 14 homolog (Chlamydomonas)
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
SLC17A2 solute carrier family 17, member 2
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SNCAIP synuclein, alpha interacting protein
SOX15 SRY (sex determining region Y)-box 15
SOX30 SRY (sex determining region Y)-box 30
SPATA6 spermatogenesis associated 6
SV2A synaptic vesicle glycoprotein 2A
SYNJ1 synaptojanin 1
SYT13 synaptotagmin XIII
SYT5 synaptotagmin V
TAS2R1 taste receptor, type 2, member 1
TBC1D2 TBC1 domain family, member 2
TCP10 t-complex 10
TDRKH tudor and KH domain containing
TEX14 testis expressed 14
TMEM242 transmembrane protein 242
TMPRSS4 transmembrane protease, serine 4
TP53I11 tumor protein p53 inducible protein 11
TPSG1 tryptase gamma 1
TRD T cell receptor delta locus
TRIM3 tripartite motif containing 3
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TSHR thyroid stimulating hormone receptor
URB1 URB1 ribosome biogenesis 1 homolog (S. cerevisiae)
VCL vinculin
VLDLR very low density lipoprotein receptor
VPS53 vacuolar protein sorting 53 homolog (S. cerevisiae)
ZFHX2 zinc finger homeobox 2
ZMIZ2 zinc finger, MIZ-type containing 2

decreased expression

Symbol Name
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
ACSL5 acyl-CoA synthetase long-chain family member 5
ACTL8 actin-like 8
ADCY7 adenylate cyclase 7
AFAP1 actin filament associated protein 1
AHDC1 AT hook, DNA binding motif, containing 1
ALOX15 arachidonate 15-lipoxygenase
ALPK1 alpha-kinase 1
ALS2CL ALS2 C-terminal like
APLP1 amyloid beta (A4) precursor-like protein 1
ARMC6 armadillo repeat containing 6
ATP10D ATPase, class V, type 10D
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
BMP15 bone morphogenetic protein 15
CA11 carbonic anhydrase XI
CAPN5 calpain 5
CCP110 centriolar coiled coil protein 110kDa
CD70 CD70 molecule
CENPQ centromere protein Q
CHML choroideremia-like (Rab escort protein 2)
CHST10 carbohydrate sulfotransferase 10
CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2
CLEC4E C-type lectin domain family 4, member E
CLIP4 CAP-GLY domain containing linker protein family, member 4
CRELD1 cysteine-rich with EGF-like domains 1
CRIP1 cysteine-rich protein 1 (intestinal)
CSRP3 cysteine and glycine-rich protein 3 (cardiac LIM protein)
CXCR2 chemokine (C-X-C motif) receptor 2
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
EPX eosinophil peroxidase
FAM155A family with sequence similarity 155, member A
FARP2 FERM, RhoGEF and pleckstrin domain protein 2
FLCN folliculin
FLRT3 fibronectin leucine rich transmembrane protein 3
FRMD1 FERM domain containing 1
FSTL3 follistatin-like 3 (secreted glycoprotein)
FURIN furin (paired basic amino acid cleaving enzyme)
FUZ fuzzy planar cell polarity protein
GPATCH2L G patch domain containing 2-like
GSTCD glutathione S-transferase, C-terminal domain containing
HIST1H2AJ histone cluster 1, H2aj
HOXC8 homeobox C8
HOXD11 homeobox D11
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IFT54 intraflagellar transport 54
IL2 interleukin 2
ITPKB inositol-trisphosphate 3-kinase B
KCNMB3 potassium channel subfamily M regulatory beta subunit 3
KIAA0319L KIAA0319-like
KLF3 Kruppel-like factor 3 (basic)
LONRF3 LON peptidase N-terminal domain and ring finger 3
LRP2 low density lipoprotein receptor-related protein 2
LRRTM2 leucine rich repeat transmembrane neuronal 2
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
MAP2 microtubule-associated protein 2
MAPK12 mitogen-activated protein kinase 12
MDM4 MDM4, p53 regulator
MMRN2 multimerin 2
NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein
NRGN neurogranin (protein kinase C substrate, RC3)
OCA2 oculocutaneous albinism II
PADI1 peptidyl arginine deiminase, type I
PDE8B phosphodiesterase 8B
PDPR pyruvate dehydrogenase phosphatase regulatory subunit
PER3 period circadian clock 3
PODNL1 podocan-like 1
POLM polymerase (DNA directed), mu
PROL1 proline rich, lacrimal 1
PRR4 proline rich 4 (lacrimal)
PSG4 pregnancy specific beta-1-glycoprotein 4
RARRES2 retinoic acid receptor responder (tazarotene induced) 2
REPS2 RALBP1 associated Eps domain containing 2
RIN2 Ras and Rab interactor 2
RLN1 relaxin 1
RNF39 ring finger protein 39
RUSC2 RUN and SH3 domain containing 2
S100A2 S100 calcium binding protein A2
S100A9 S100 calcium binding protein A9
SCN10A sodium channel, voltage gated, type X alpha subunit
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SLC16A10 solute carrier family 16 (aromatic amino acid transporter), member 10
SLC25A21 solute carrier family 25 (mitochondrial oxoadipate carrier), member 21
SLC2A9 solute carrier family 2 (facilitated glucose transporter), member 9
SPATA1 spermatogenesis associated 1
TGFBR1 transforming growth factor, beta receptor 1
TNS2 tensin 2
TREM1 triggering receptor expressed on myeloid cells 1
TSC22D4 TSC22 domain family, member 4
TTBK2 tau tubulin kinase 2
UNC93B1 unc-93 homolog B1 (C. elegans)
VGF VGF nerve growth factor inducible
VIM vimentin
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
ZDHHC14 zinc finger, DHHC-type containing 14
ZNF506 zinc finger protein 506
ZNF750 zinc finger protein 750