iohexol Gene Set

Dataset	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures
Category	transcriptomics
Type	small molecule perturbation
Description	A benzenedicarboxamide compound having N-(2,3-dihydroxypropyl)carbamoyl groups at the 1- and 3-positions, iodo substituents at the 2-, 4- and 6-positions and an N-(2,3-dihydroxypropyl)acetamido group at the 5-position. (Chemical Entities of Biological Interest Ontology, CHEBI_31709)
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Genes

8 genes differentially expressed following the iohexol small molecule perturbation from the LINCS L1000 CMAP Chemical Perturbation Consensus Signatures dataset.

increased expression

Symbol	Name	Standardized Value
TIE1	tyrosine kinase with immunoglobulin-like and EGF-like domains 1	3.3269
CHRNB3	cholinergic receptor, nicotinic, beta 3 (neuronal)	3.04996
SMC1A	structural maintenance of chromosomes 1A	3.04895
ADGRL4	adhesion G protein-coupled receptor L4	3.04783
KLF2	Kruppel-like factor 2	3.04462

decreased expression

Symbol	Name	Standardized Value
CEMIP2	cell migration inducing hyaluronidase 2	-3.61592
CASK	calcium/calmodulin-dependent serine protein kinase (MAGUK family)	-3.17557
RASGRF1	Ras protein-specific guanine nucleotide-releasing factor 1	-3.04236