ion channel inhibitor activity Gene Set

Dataset GO Molecular Function Annotations 2025
Category structural or functional annotations
Type molecular function
Description Stops, prevents, or reduces the activity of an ion channel. (Gene Ontology, GO_0008200)
External Link http://amigo.geneontology.org/amigo/term/GO:0008200
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Genes

41 genes performing the ion channel inhibitor activity molecular function from the curated GO Molecular Function Annotations 2025 dataset.

Symbol Name
AMBP alpha-1-microglobulin/bikunin precursor
ANKRD36C ankyrin repeat domain 36C
ANO9 anoctamin 9
CALM1 calmodulin 1 (phosphorylase kinase, delta)
CALM2 calmodulin 2 (phosphorylase kinase, delta)
CAMK2D calcium/calmodulin-dependent protein kinase II delta
CAV3 caveolin 3
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
COMMD1 copper metabolism (Murr1) domain containing 1
ENSA endosulfine alpha
FKBP1B FK506 binding protein 1B, 12.6 kDa
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
KCNE4 potassium channel, voltage gated subfamily E regulatory beta subunit 4
KCNK2 potassium channel, two pore domain subfamily K, member 2
KCNMB3 potassium channel subfamily M regulatory beta subunit 3
KCNV1 potassium channel, voltage gated modifier subfamily V, member 1
LAMP1 lysosomal-associated membrane protein 1
LAMP2 lysosomal-associated membrane protein 2
MCUB mitochondrial calcium uniporter dominant negative subunit beta
MICU1 mitochondrial calcium uptake 1
NEDD4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
NHERF4 NHERF family PDZ scaffold protein 4
PACSIN3 protein kinase C and casein kinase substrate in neurons 3
PCSK9 proprotein convertase subtilisin/kexin type 9
PHPT1 phosphohistidine phosphatase 1
RACK1 receptor for activated C kinase 1
RSC1A1 regulatory solute carrier protein, family 1, member 1
SCN1B sodium channel, voltage gated, type I beta subunit
SCN3B sodium channel, voltage gated, type III beta subunit
SLC30A1 solute carrier family 30 (zinc transporter), member 1
STX1A syntaxin 1A (brain)
STX7 syntaxin 7
STX8 syntaxin 8
SYNGAP1 synaptic Ras GTPase activating protein 1
TMC7 transmembrane channel-like 7
TNNI3 troponin I type 3 (cardiac)
VAMP8 vesicle-associated membrane protein 8
VTI1B vesicle transport through interaction with t-SNAREs 1B
WNK4 WNK lysine deficient protein kinase 4
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon