ionomycin-979 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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198 genes differentially expressed following the ionomycin-979 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ANG angiogenin, ribonuclease, RNase A family, 5
ARFGAP3 ADP-ribosylation factor GTPase activating protein 3
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
ARMCX3 armadillo repeat containing, X-linked 3
ATF3 activating transcription factor 3
ATG3 autophagy related 3
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
ATXN1 ataxin 1
C16ORF45 chromosome 16 open reading frame 45
CDC6 cell division cycle 6
CDK2AP2 cyclin-dependent kinase 2 associated protein 2
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CREB3L2 cAMP responsive element binding protein 3-like 2
CRELD1 cysteine-rich with EGF-like domains 1
CRELD2 cysteine-rich with EGF-like domains 2
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3
DUSP4 dual specificity phosphatase 4
EAF2 ELL associated factor 2
EDEM1 ER degradation enhancer, mannosidase alpha-like 1
EDEM2 ER degradation enhancer, mannosidase alpha-like 2
EPAS1 endothelial PAS domain protein 1
ERP44 endoplasmic reticulum protein 44
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
ETV5 ets variant 5
FICD FIC domain containing
FKBP14 FK506 binding protein 14, 22 kDa
FLJ42627 uncharacterized LOC645644
FNDC3B fibronectin type III domain containing 3B
FYN FYN proto-oncogene, Src family tyrosine kinase
GADD45A growth arrest and DNA-damage-inducible, alpha
GLRX glutaredoxin (thioltransferase)
GMPPA GDP-mannose pyrophosphorylase A
GMPPB GDP-mannose pyrophosphorylase B
GRB10 growth factor receptor-bound protein 10
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1
HSPA13 heat shock protein 70kDa family, member 13
HYOU1 hypoxia up-regulated 1
ICAM1 intercellular adhesion molecule 1
INHBE inhibin, beta E
ISG20 interferon stimulated exonuclease gene 20kDa
KRT17 keratin 17, type I
LARP6 La ribonucleoprotein domain family, member 6
LIN7B lin-7 homolog B (C. elegans)
LZTFL1 leucine zipper transcription factor-like 1
MANF mesencephalic astrocyte-derived neurotrophic factor
MAP1B microtubule-associated protein 1B
MBNL2 muscleblind-like splicing regulator 2
MED6 mediator complex subunit 6
MGAT2 mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
MIR22HG MIR22 host gene
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NUCB2 nucleobindin 2
NUPR1 nuclear protein, transcriptional regulator, 1
PDGFRL platelet-derived growth factor receptor-like
PDIA4 protein disulfide isomerase family A, member 4
PGM3 phosphoglucomutase 3
PHLDA1 pleckstrin homology-like domain, family A, member 1
PLA2G3 phospholipase A2, group III
PRNP prion protein
PRODH proline dehydrogenase (oxidase) 1
PRSS16 protease, serine, 16 (thymus)
RCAN1 regulator of calcineurin 1
RHOQ ras homolog family member Q
RNASE4 ribonuclease, RNase A family, 4
RRBP1 ribosome binding protein 1
SDF2L1 stromal cell-derived factor 2-like 1
SEC24D SEC24 family member D
SEL1L sel-1 suppressor of lin-12-like (C. elegans)
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6
SLC33A1 solute carrier family 33 (acetyl-CoA transporter), member 1
SLC39A14 solute carrier family 39 (zinc transporter), member 14
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SNAI2 snail family zinc finger 2
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STARD5 StAR-related lipid transfer (START) domain containing 5
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TES testin LIM domain protein
TFPI2 tissue factor pathway inhibitor 2
THBD thrombomodulin
TMED7 transmembrane emp24 protein transport domain containing 7
TMEM39A transmembrane protein 39A
TRIB3 tribbles pseudokinase 3
TRIM2 tripartite motif containing 2
TSPYL2 TSPY-like 2
TUBA3C tubulin, alpha 3c
USP36 ubiquitin specific peptidase 36
VEGFA vascular endothelial growth factor A
WIPI1 WD repeat domain, phosphoinositide interacting 1
ZNF165 zinc finger protein 165
ZNF365 zinc finger protein 365
ZNF592 zinc finger protein 592

decreased expression

Symbol Name
ACVR2B activin A receptor, type IIB
ADGRL2 adhesion G protein-coupled receptor L2
ALAD aminolevulinate dehydratase
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26
ARNTL2 aryl hydrocarbon receptor nuclear translocator-like 2
ARRB1 arrestin, beta 1
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila)
BHLHB9 basic helix-loop-helix domain containing, class B, 9
BMP4 bone morphogenetic protein 4
BRINP3 bone morphogenetic protein/retinoic acid inducible neural-specific 3
C1GALT1 core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1
C1ORF106 chromosome 1 open reading frame 106
C1ORF35 chromosome 1 open reading frame 35
C21ORF91 chromosome 21 open reading frame 91
CA11 carbonic anhydrase XI
CA2 carbonic anhydrase II
CCDC88C coiled-coil domain containing 88C
CCP110 centriolar coiled coil protein 110kDa
CEP131 centrosomal protein 131kDa
CIR1 corepressor interacting with RBPJ, 1
CLSPN claspin
CTSK cathepsin K
CXCR4 chemokine (C-X-C motif) receptor 4
DEGS1 delta(4)-desaturase, sphingolipid 1
DNA2 DNA replication helicase/nuclease 2
DZANK1 double zinc ribbon and ankyrin repeat domains 1
E2F8 E2F transcription factor 8
EIF5A2 eukaryotic translation initiation factor 5A2
ELOVL4 ELOVL fatty acid elongase 4
FAAH fatty acid amide hydrolase
FAM111A family with sequence similarity 111, member A
FAM155B family with sequence similarity 155, member B
FAM192A family with sequence similarity 192, member A
FBXO3 F-box protein 3
FKBP5 FK506 binding protein 5
FUZ fuzzy planar cell polarity protein
GATA6 GATA binding protein 6
GCA grancalcin, EF-hand calcium binding protein
GLCE glucuronic acid epimerase
GNA13 guanine nucleotide binding protein (G protein), alpha 13
HELLS helicase, lymphoid-specific
HIST1H3G histone cluster 1, H3g
HSPA1A heat shock 70kDa protein 1A
HSPA1L heat shock 70kDa protein 1-like
HSPA2 heat shock 70kDa protein 2
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
ICK intestinal cell (MAK-like) kinase
IFT81 intraflagellar transport 81
KCNMB3 potassium channel subfamily M regulatory beta subunit 3
KIAA1551 KIAA1551
KIF14 kinesin family member 14
METTL2B methyltransferase like 2B
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
MOSPD3 motile sperm domain containing 3
MRPL17 mitochondrial ribosomal protein L17
MTA2 metastasis associated 1 family, member 2
MTERF1 mitochondrial transcription termination factor 1
MTRF1 mitochondrial translational release factor 1
NBEAL2 neurobeachin-like 2
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NPY1R neuropeptide Y receptor Y1
PAFAH1B2 platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa)
PAQR4 progestin and adipoQ receptor family member IV
PARD6A par-6 family cell polarity regulator alpha
PARPBP PARP1 binding protein
PER3 period circadian clock 3
PEX11A peroxisomal biogenesis factor 11 alpha
PHC1 polyhomeotic homolog 1 (Drosophila)
PKIA protein kinase (cAMP-dependent, catalytic) inhibitor alpha
PLA2G15 phospholipase A2, group XV
PLCXD1 phosphatidylinositol-specific phospholipase C, X domain containing 1
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
PP14571 uncharacterized LOC100130449
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PROCR protein C receptor, endothelial
PRR15L proline rich 15-like
RECQL4 RecQ protein-like 4
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
RIBC2 RIB43A domain with coiled-coils 2
RIPPLY3 ripply transcriptional repressor 3
RRAGB Ras-related GTP binding B
RRNAD1 ribosomal RNA adenine dimethylase domain containing 1
SECISBP2 SECIS binding protein 2
SLC25A40 solute carrier family 25, member 40
SLC6A14 solute carrier family 6 (amino acid transporter), member 14
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
SNRPF small nuclear ribonucleoprotein polypeptide F
SNX7 sorting nexin 7
SP140L SP140 nuclear body protein-like
SYCP2 synaptonemal complex protein 2
TDRD7 tudor domain containing 7
TFF3 trefoil factor 3 (intestinal)
TRMU tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
TTBK2 tau tubulin kinase 2
ZBTB6 zinc finger and BTB domain containing 6
ZKSCAN3 zinc finger with KRAB and SCAN domains 3
ZNF253 zinc finger protein 253
ZNF639 zinc finger protein 639