ionomycin Gene Set

Dataset Phosphosite Textmining Biological Term Annotations
Category structural or functional annotations
Type biological term
Description A very long-chain fatty acid that is docosa-10,16-dienoic acid which is substituted by methyl groups at positions 4, 6, 8, 12, 14, 18 and 20, by hydroxy groups at positions 11, 19 and 21, and by a (2',5-dimethyloctahydro-2,2'-bifuran-5-yl)ethanol group at position 21. An ionophore produced by Streptomyces conglobatus, it is used in research to raise the intracellular level of Ca(2+) and as a research tool to understand Ca(2+) transport across biological membranes. (Chemical Entities of Biological Interest Ontology, CHEBI_63954)
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Genes

56 proteins co-occuring with the biological term ionomycin in abstracts of publications describing phosphosites from the Phosphosite Textmining Biological Term Annotations dataset.

Symbol Name
ABI1 abl-interactor 1
ACACA acetyl-CoA carboxylase alpha
AKT1 v-akt murine thymoma viral oncogene homolog 1
ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide
BCL10 B-cell CLL/lymphoma 10
CAMK1 calcium/calmodulin-dependent protein kinase I
CAMK1D calcium/calmodulin-dependent protein kinase ID
CAMK2A calcium/calmodulin-dependent protein kinase II alpha
CAMK2D calcium/calmodulin-dependent protein kinase II delta
CD28 CD28 molecule
CD3G CD3g molecule, gamma (CD3-TCR complex)
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CREB1 cAMP responsive element binding protein 1
DUSP16 dual specificity phosphatase 16
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
IKZF1 IKAROS family zinc finger 1 (Ikaros)
IRAK1 interleukin-1 receptor-associated kinase 1
IRS1 insulin receptor substrate 1
KCNB1 potassium channel, voltage gated Shab related subfamily B, member 1
KCNK18 potassium channel, two pore domain subfamily K, member 18
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
LCK LCK proto-oncogene, Src family tyrosine kinase
MAP3K5 mitogen-activated protein kinase kinase kinase 5
MAPK1 mitogen-activated protein kinase 1
MAPK14 mitogen-activated protein kinase 14
MAPK3 mitogen-activated protein kinase 3
MAPK8 mitogen-activated protein kinase 8
MARK2 MAP/microtubule affinity-regulating kinase 2
MYH9 myosin, heavy chain 9, non-muscle
MYL12B myosin, light chain 12B, regulatory
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
NFATC2 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NOS3 nitric oxide synthase 3 (endothelial cell)
NOX5 NADPH oxidase, EF-hand calcium binding domain 5
NUMB numb homolog (Drosophila)
NUMBL numb homolog (Drosophila)-like
OPRD1 opioid receptor, delta 1
PDPK1 3-phosphoinositide dependent protein kinase 1
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLN phospholamban
PNPLA8 patatin-like phospholipase domain containing 8
POU2AF1 POU class 2 associating factor 1
PPP1R12A protein phosphatase 1, regulatory subunit 12A
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit
PRKCQ protein kinase C, theta
PTK2 protein tyrosine kinase 2
PTK2B protein tyrosine kinase 2 beta
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
S100A9 S100 calcium binding protein A9
SMAD2 SMAD family member 2
SRC SRC proto-oncogene, non-receptor tyrosine kinase
STMN1 stathmin 1
VIM vimentin