iopamidol-5832 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the iopamidol-5832 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACOT11 acyl-CoA thioesterase 11
ADGRF5 adhesion G protein-coupled receptor F5
AHI1 Abelson helper integration site 1
ALK anaplastic lymphoma receptor tyrosine kinase
AMBRA1 autophagy/beclin-1 regulator 1
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha
ASTN2 astrotactin 2
ATG16L1 autophagy related 16-like 1 (S. cerevisiae)
ATP2B3 ATPase, Ca++ transporting, plasma membrane 3
B4GALT6 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6
BAIAP2 BAI1-associated protein 2
BIN1 bridging integrator 1
BMP2K BMP2 inducible kinase
BTBD18 BTB (POZ) domain containing 18
CDHR2 cadherin-related family member 2
CEP68 centrosomal protein 68kDa
CFLAR CASP8 and FADD-like apoptosis regulator
CHEK2 checkpoint kinase 2
CLN5 ceroid-lipofuscinosis, neuronal 5
COL6A1 collagen, type VI, alpha 1
COPG2IT1 COPG2 imprinted transcript 1 (non-protein coding)
CRYBB2P1 crystallin, beta B2 pseudogene 1
CYP4F8 cytochrome P450, family 4, subfamily F, polypeptide 8
DCAF11 DDB1 and CUL4 associated factor 11
DCAF17 DDB1 and CUL4 associated factor 17
DHRS7 dehydrogenase/reductase (SDR family) member 7
EMC3 ER membrane protein complex subunit 3
EML3 echinoderm microtubule associated protein like 3
ESR1 estrogen receptor 1
FAM50B family with sequence similarity 50, member B
FCER2 Fc fragment of IgE, low affinity II, receptor for (CD23)
FGFR1 fibroblast growth factor receptor 1
GALK2 galactokinase 2
GGA2 golgi-associated, gamma adaptin ear containing, ARF binding protein 2
GPR17 G protein-coupled receptor 17
IFI6 interferon, alpha-inducible protein 6
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IFITM1 interferon induced transmembrane protein 1
IGFBP5 insulin-like growth factor binding protein 5
IKZF1 IKAROS family zinc finger 1 (Ikaros)
IL11RA interleukin 11 receptor, alpha
IL1R2 interleukin 1 receptor, type II
IRF4 interferon regulatory factor 4
KDM4C lysine (K)-specific demethylase 4C
KLF12 Kruppel-like factor 12
L3MBTL1 l(3)mbt-like 1 (Drosophila)
LOC647070 uncharacterized LOC647070
MAPK10 mitogen-activated protein kinase 10
MECOM MDS1 and EVI1 complex locus
MMP13 matrix metallopeptidase 13
NEFM neurofilament, medium polypeptide
NF2 neurofibromin 2 (merlin)
NPTX1 neuronal pentraxin I
NPY6R neuropeptide Y receptor Y6 (pseudogene)
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa
PAFAH2 platelet-activating factor acetylhydrolase 2, 40kDa
PALMD palmdelphin
PASK PAS domain containing serine/threonine kinase
PCM1 pericentriolar material 1
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent)
PPP4R4 protein phosphatase 4, regulatory subunit 4
PRUNE2 prune homolog 2 (Drosophila)
RABEP1 rabaptin, RAB GTPase binding effector protein 1
RANBP1 RAN binding protein 1
RNF146 ring finger protein 146
RPL3L ribosomal protein L3-like
SARM1 sterile alpha and TIR motif containing 1
SBNO1 strawberry notch homolog 1 (Drosophila)
SEMA4G sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
SIRT3 sirtuin 3
SLC25A44 solute carrier family 25, member 44
SLC43A1 solute carrier family 43 (amino acid system L transporter), member 1
SLC46A3 solute carrier family 46, member 3
SLC6A20 solute carrier family 6 (proline IMINO transporter), member 20
SLC9A5 solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5
SMAD4 SMAD family member 4
SP110 SP110 nuclear body protein
SSH3 slingshot protein phosphatase 3
SSTR4 somatostatin receptor 4
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
ST6GALNAC4 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4
TBC1D9B TBC1 domain family, member 9B (with GRAM domain)
TDRKH tudor and KH domain containing
TLE3 transducin-like enhancer of split 3
TMCC1 transmembrane and coiled-coil domain family 1
TMEM120B transmembrane protein 120B
TPD52 tumor protein D52
TPM2 tropomyosin 2 (beta)
TROVE2 TROVE domain family, member 2
VNN2 vanin 2
WDR1 WD repeat domain 1
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase
YIPF4 Yip1 domain family, member 4
ZFX zinc finger protein, X-linked
ZMYND11 zinc finger, MYND-type containing 11
ZNF10 zinc finger protein 10
ZNF492 zinc finger protein 492

decreased expression

Symbol Name
ACVR2B activin A receptor, type IIB
ADAM15 ADAM metallopeptidase domain 15
ALPK1 alpha-kinase 1
ALS2CL ALS2 C-terminal like
AP3B1 adaptor-related protein complex 3, beta 1 subunit
ARHGEF10L Rho guanine nucleotide exchange factor (GEF) 10-like
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
BAG4 BCL2-associated athanogene 4
BATF3 basic leucine zipper transcription factor, ATF-like 3
BFAR bifunctional apoptosis regulator
BIK BCL2-interacting killer (apoptosis-inducing)
BMP15 bone morphogenetic protein 15
BTF3P12 basic transcription factor 3 pseudogene 12
C16ORF59 chromosome 16 open reading frame 59
CCS copper chaperone for superoxide dismutase
CDKN2AIP CDKN2A interacting protein
CISH cytokine inducible SH2-containing protein
CLDN8 claudin 8
COBL cordon-bleu WH2 repeat protein
CRYL1 crystallin, lambda 1
CSNK1E casein kinase 1, epsilon
CTAGE9 CTAGE family, member 9
CUL9 cullin 9
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1
DCAF13 DDB1 and CUL4 associated factor 13
DEPTOR DEP domain containing MTOR-interacting protein
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2
EAF2 ELL associated factor 2
EFNA1 ephrin-A1
EGLN2 egl-9 family hypoxia-inducible factor 2
EHMT2 euchromatic histone-lysine N-methyltransferase 2
ERF Ets2 repressor factor
GBF1 golgi brefeldin A resistant guanine nucleotide exchange factor 1
GPR3 G protein-coupled receptor 3
GTPBP6 GTP binding protein 6 (putative)
HIST1H1T histone cluster 1, H1t
HIST3H2A histone cluster 3, H2a
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HOXC13 homeobox C13
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
IL17RB interleukin 17 receptor B
KCTD15 potassium channel tetramerization domain containing 15
KLHL26 kelch-like family member 26
KLHL36 kelch-like family member 36
LAMA5 laminin, alpha 5
LHPP phospholysine phosphohistidine inorganic pyrophosphate phosphatase
LOC100127972 uncharacterized LOC100127972
LYPLA2P1 lysophospholipase II pseudogene 1
MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2
MICALL2 MICAL-like 2
MRPL28 mitochondrial ribosomal protein L28
MTMR11 myotubularin related protein 11
MYO1D myosin ID
NCS1 neuronal calcium sensor 1
NHEJ1 nonhomologous end-joining factor 1
NOTCH1 notch 1
NRSN2 neurensin 2
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
PADI1 peptidyl arginine deiminase, type I
PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime
PDGFRL platelet-derived growth factor receptor-like
PLEKHO2 pleckstrin homology domain containing, family O member 2
POLA1 polymerase (DNA directed), alpha 1, catalytic subunit
PRMT7 protein arginine methyltransferase 7
RAI2 retinoic acid induced 2
RFX7 regulatory factor X, 7
RNF126P1 ring finger protein 126 pseudogene 1
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1
RPAP1 RNA polymerase II associated protein 1
SH3TC2 SH3 domain and tetratricopeptide repeats 2
SLC12A9 solute carrier family 12, member 9
SLC27A3 solute carrier family 27 (fatty acid transporter), member 3
SPEG SPEG complex locus
STBD1 starch binding domain 1
STEAP4 STEAP family member 4
TINF2 TERF1 (TRF1)-interacting nuclear factor 2
TKFC triokinase/FMN cyclase
TLN1 talin 1
TMEM212 transmembrane protein 212
TMEM51 transmembrane protein 51
TNRC6B trinucleotide repeat containing 6B
TPRA1 transmembrane protein, adipocyte asscociated 1
TRABD TraB domain containing
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TSPYL2 TSPY-like 2
TTC31 tetratricopeptide repeat domain 31
TTLL7 tubulin tyrosine ligase-like family member 7
TXNL4B thioredoxin-like 4B
UGGT2 UDP-glucose glycoprotein glucosyltransferase 2
ULK1 unc-51 like autophagy activating kinase 1
VASH2 vasohibin 2
VEZT vezatin, adherens junctions transmembrane protein
ZBED1 zinc finger, BED-type containing 1
ZNF408 zinc finger protein 408
ZNF426 zinc finger protein 426
ZNF611 zinc finger protein 611
ZNF668 zinc finger protein 668