iopanoic acid-5448 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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198 genes differentially expressed following the iopanoic acid-5448 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase
ACRV1 acrosomal vesicle protein 1
ADGRG1 adhesion G protein-coupled receptor G1
AKAP8L A kinase (PRKA) anchor protein 8-like
APOC4 apolipoprotein C-IV
APOL2 apolipoprotein L, 2
ARHGAP4 Rho GTPase activating protein 4
B3GNTL1 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1
BCL2A1 BCL2-related protein A1
BMP2K BMP2 inducible kinase
C11ORF21 chromosome 11 open reading frame 21
CA5B carbonic anhydrase VB, mitochondrial
CALML3 calmodulin-like 3
CAMP cathelicidin antimicrobial peptide
CD4 CD4 molecule
CD58 CD58 molecule
CDRT1 CMT1A duplicated region transcript 1
CFAP70 cilia and flagella associated protein 70
CNOT3 CCR4-NOT transcription complex, subunit 3
CPS1 carbamoyl-phosphate synthase 1, mitochondrial
CSHL1 chorionic somatomammotropin hormone-like 1
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DGKA diacylglycerol kinase, alpha 80kDa
DHX34 DEAH (Asp-Glu-Ala-His) box polypeptide 34
DOK5 docking protein 5
DTNA dystrobrevin, alpha
DUSP6 dual specificity phosphatase 6
EDNRA endothelin receptor type A
EPHA1 EPH receptor A1
EPS8L3 EPS8-like 3
ERAP1 endoplasmic reticulum aminopeptidase 1
ERO1LB ERO1-like beta (S. cerevisiae)
EXT1 exostosin glycosyltransferase 1
FBXL7 F-box and leucine-rich repeat protein 7
FOXP3 forkhead box P3
GNA14 guanine nucleotide binding protein (G protein), alpha 14
GSTTP1 glutathione S-transferase theta pseudogene 1
GTDC1 glycosyltransferase-like domain containing 1
HIST1H2BN histone cluster 1, H2bn
HOXB6 homeobox B6
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
IGKV3-20 immunoglobulin kappa variable 3-20
ING4 inhibitor of growth family, member 4
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2
KCNJ3 potassium channel, inwardly rectifying subfamily J, member 3
KDM8 lysine (K)-specific demethylase 8
KLRF1 killer cell lectin-like receptor subfamily F, member 1
KPNA6 karyopherin alpha 6 (importin alpha 7)
LOC644450 uncharacterized LOC644450
LTC4S leukotriene C4 synthase
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2
MAP4 microtubule-associated protein 4
MAPRE3 microtubule-associated protein, RP/EB family, member 3
MBL2 mannose-binding lectin (protein C) 2, soluble
MID1 midline 1
MSMB microseminoprotein, beta-
MTAP methylthioadenosine phosphorylase
NDUFAF5 NADH dehydrogenase (ubiquinone) complex I, assembly factor 5
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NIPSNAP3B nipsnap homolog 3B (C. elegans)
NR6A1 nuclear receptor subfamily 6, group A, member 1
NXPH3 neurexophilin 3
OLFML2A olfactomedin-like 2A
PALM paralemmin
PCM1 pericentriolar material 1
PENK proenkephalin
PER1 period circadian clock 1
PEX10 peroxisomal biogenesis factor 10
PLD1 phospholipase D1, phosphatidylcholine-specific
PLEKHO2 pleckstrin homology domain containing, family O member 2
PLP1 proteolipid protein 1
PLSCR4 phospholipid scramblase 4
PPARD peroxisome proliferator-activated receptor delta
PYHIN1 pyrin and HIN domain family, member 1
RAB3GAP2 RAB3 GTPase activating protein subunit 2 (non-catalytic)
RELN reelin
S100A7 S100 calcium binding protein A7
S100A8 S100 calcium binding protein A8
SCUBE3 signal peptide, CUB domain, EGF-like 3
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
SEMA6A sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
SH3GL3 SH3-domain GRB2-like 3
SHANK1 SH3 and multiple ankyrin repeat domains 1
SIGLEC8 sialic acid binding Ig-like lectin 8
SLC16A4 solute carrier family 16, member 4
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
STK17B serine/threonine kinase 17b
TAAR5 trace amine associated receptor 5
TGFBR1 transforming growth factor, beta receptor 1
TMEM40 transmembrane protein 40
TNFAIP2 tumor necrosis factor, alpha-induced protein 2
TRA T cell receptor alpha locus
TRIL TLR4 interactor with leucine-rich repeats
TRPM2 transient receptor potential cation channel, subfamily M, member 2
UROD uroporphyrinogen decarboxylase
WIPI2 WD repeat domain, phosphoinositide interacting 2
YOD1 YOD1 deubiquitinase
ZNF76 zinc finger protein 76
ZSCAN2 zinc finger and SCAN domain containing 2

decreased expression

Symbol Name
A2M alpha-2-macroglobulin
ACBD4 acyl-CoA binding domain containing 4
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
AOC2 amine oxidase, copper containing 2 (retina-specific)
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17
ARMC4 armadillo repeat containing 4
ASB1 ankyrin repeat and SOCS box containing 1
C22ORF46 chromosome 22 open reading frame 46
C5ORF45 chromosome 5 open reading frame 45
CAMTA2 calmodulin binding transcription activator 2
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2)
CIC capicua transcriptional repressor
CLCF1 cardiotrophin-like cytokine factor 1
CORT cortistatin
CPSF7 cleavage and polyadenylation specific factor 7, 59kDa
CRABP1 cellular retinoic acid binding protein 1
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
DGKE diacylglycerol kinase, epsilon 64kDa
DHRS3 dehydrogenase/reductase (SDR family) member 3
DMTN dematin actin binding protein
DSCAM Down syndrome cell adhesion molecule
ETAA1 Ewing tumor-associated antigen 1
FANCE Fanconi anemia, complementation group E
FGD1 FYVE, RhoGEF and PH domain containing 1
FOSL1 FOS-like antigen 1
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12
GFPT2 glutamine-fructose-6-phosphate transaminase 2
GPR27 G protein-coupled receptor 27
HIST1H2AK histone cluster 1, H2ak
HIST1H4A histone cluster 1, H4a
IFITM1 interferon induced transmembrane protein 1
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
INO80D INO80 complex subunit D
INPP5J inositol polyphosphate-5-phosphatase J
IPO8 importin 8
IRF1 interferon regulatory factor 1
KCNF1 potassium channel, voltage gated modifier subfamily F, member 1
KIAA0125 KIAA0125
KIAA0754 KIAA0754
KLF2 Kruppel-like factor 2
KLHL25 kelch-like family member 25
KPNA5 karyopherin alpha 5 (importin alpha 6)
LEFTY1 left-right determination factor 1
LHPP phospholysine phosphohistidine inorganic pyrophosphate phosphatase
LIN7B lin-7 homolog B (C. elegans)
LOC100286895 cell division cycle 27 homolog pseudogene
LRP2 low density lipoprotein receptor-related protein 2
LRRC6 leucine rich repeat containing 6
LY6D lymphocyte antigen 6 complex, locus D
MRPL41 mitochondrial ribosomal protein L41
NIPAL2 NIPA-like domain containing 2
NKAIN1 Na+/K+ transporting ATPase interacting 1
NOD1 nucleotide-binding oligomerization domain containing 1
NPTX1 neuronal pentraxin I
NT5DC3 5'-nucleotidase domain containing 3
OGFRL1 opioid growth factor receptor-like 1
PCDHA6 protocadherin alpha 6
PDE12 phosphodiesterase 12
PIGN phosphatidylinositol glycan anchor biosynthesis, class N
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PNPLA6 patatin-like phospholipase domain containing 6
PPT2 palmitoyl-protein thioesterase 2
PRODH proline dehydrogenase (oxidase) 1
PSG4 pregnancy specific beta-1-glycoprotein 4
PSTPIP2 proline-serine-threonine phosphatase interacting protein 2
PTPRE protein tyrosine phosphatase, receptor type, E
RIN1 Ras and Rab interactor 1
RIN2 Ras and Rab interactor 2
RNF170 ring finger protein 170
RNF39 ring finger protein 39
RPL10L ribosomal protein L10-like
RUSC2 RUN and SH3 domain containing 2
SCN1B sodium channel, voltage gated, type I beta subunit
SIK1 salt-inducible kinase 1
SKI SKI proto-oncogene
SKIV2L superkiller viralicidic activity 2-like (S. cerevisiae)
SLC16A10 solute carrier family 16 (aromatic amino acid transporter), member 10
SLN sarcolipin
SNAI2 snail family zinc finger 2
SPON2 spondin 2, extracellular matrix protein
STBD1 starch binding domain 1
STEAP1 six transmembrane epithelial antigen of the prostate 1
STEAP4 STEAP family member 4
STRA6 stimulated by retinoic acid 6
TAOK1 TAO kinase 1
TGFBI transforming growth factor, beta-induced, 68kDa
TMEM242 transmembrane protein 242
TRAIP TRAF interacting protein
TRPV6 transient receptor potential cation channel, subfamily V, member 6
TTC33 tetratricopeptide repeat domain 33
ULBP2 UL16 binding protein 2
UPP1 uridine phosphorylase 1
USB1 U6 snRNA biogenesis 1
VASH1 vasohibin 1
ZBTB48 zinc finger and BTB domain containing 48
ZKSCAN3 zinc finger with KRAB and SCAN domains 3
ZNF696 zinc finger protein 696
ZNF701 zinc finger protein 701