iopromide-2739 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the iopromide-2739 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAK1 AP2 associated kinase 1
AASS aminoadipate-semialdehyde synthase
ADGRB1 adhesion G protein-coupled receptor B1
ALDH6A1 aldehyde dehydrogenase 6 family, member A1
ALDOB aldolase B, fructose-bisphosphate
ANGPT2 angiopoietin 2
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
BRF1 BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit
C14ORF1 chromosome 14 open reading frame 1
C14ORF105 chromosome 14 open reading frame 105
CACNB4 calcium channel, voltage-dependent, beta 4 subunit
CALML3 calmodulin-like 3
CCL19 chemokine (C-C motif) ligand 19
CD6 CD6 molecule
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CEMP1 cementum protein 1
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal)
CLDN3 claudin 3
COL1A1 collagen, type I, alpha 1
CSHL1 chorionic somatomammotropin hormone-like 1
CST1 cystatin SN
CYP39A1 cytochrome P450, family 39, subfamily A, polypeptide 1
CYP4F8 cytochrome P450, family 4, subfamily F, polypeptide 8
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase)
DLGAP1 discs, large (Drosophila) homolog-associated protein 1
EHMT1 euchromatic histone-lysine N-methyltransferase 1
FGF4 fibroblast growth factor 4
FGF6 fibroblast growth factor 6
FGFR2 fibroblast growth factor receptor 2
GEM GTP binding protein overexpressed in skeletal muscle
GNAT1 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1
GPM6B glycoprotein M6B
GUCA2A guanylate cyclase activator 2A (guanylin)
HEYL hes-related family bHLH transcription factor with YRPW motif-like
HIST1H2AJ histone cluster 1, H2aj
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HNRNPDL heterogeneous nuclear ribonucleoprotein D-like
HOXC13 homeobox C13
IFT54 intraflagellar transport 54
IGHA1 immunoglobulin heavy constant alpha 1
IGHM immunoglobulin heavy constant mu
IL1R1 interleukin 1 receptor, type I
IL1RAPL2 interleukin 1 receptor accessory protein-like 2
IL1RN interleukin 1 receptor antagonist
INSR insulin receptor
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3
KCNH6 potassium channel, voltage gated eag related subfamily H, member 6
KIAA1456 KIAA1456
KIF1C kinesin family member 1C
KLC2 kinesin light chain 2
KLHL22 kelch-like family member 22
KRTAP5-9 keratin associated protein 5-9
LY6G6C lymphocyte antigen 6 complex, locus G6C
MAPT microtubule-associated protein tau
MBNL1 muscleblind-like splicing regulator 1
MIR622 microRNA 622
MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4
MRAS muscle RAS oncogene homolog
NCOR2 nuclear receptor corepressor 2
NLGN1 neuroligin 1
NPPB natriuretic peptide B
NRG1 neuregulin 1
NRP1 neuropilin 1
OCA2 oculocutaneous albinism II
PAX1 paired box 1
PBOV1 prostate and breast cancer overexpressed 1
PDE4DIP phosphodiesterase 4D interacting protein
PDLIM5 PDZ and LIM domain 5
PHYHIP phytanoyl-CoA 2-hydroxylase interacting protein
PICALM phosphatidylinositol binding clathrin assembly protein
PIGO phosphatidylinositol glycan anchor biosynthesis, class O
PPP1R2P9 protein phosphatase 1, regulatory (inhibitor) subunit 2 pseudogene 9
PRDX2 peroxiredoxin 2
PTGER3 prostaglandin E receptor 3 (subtype EP3)
RAB11B RAB11B, member RAS oncogene family
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
RPS6 ribosomal protein S6
SCN2B sodium channel, voltage gated, type II beta subunit
SFRP5 secreted frizzled-related protein 5
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2
SPAG8 sperm associated antigen 8
SPTLC3 serine palmitoyltransferase, long chain base subunit 3
STS steroid sulfatase (microsomal), isozyme S
SUGCT succinyl-CoA:glutarate-CoA transferase
SULT1C2 sulfotransferase family, cytosolic, 1C, member 2
SUPT20H suppressor of Ty 20 homolog (S. cerevisiae)
TBKBP1 TBK1 binding protein 1
TESPA1 thymocyte expressed, positive selection associated 1
TIGD6 tigger transposable element derived 6
TMEM212 transmembrane protein 212
TPD52L1 tumor protein D52-like 1
TRPC2 transient receptor potential cation channel, subfamily C, member 2, pseudogene
TSPYL5 TSPY-like 5
VWA1 von Willebrand factor A domain containing 1
ZNF407 zinc finger protein 407
ZNF44 zinc finger protein 44
ZNF81 zinc finger protein 81

decreased expression

Symbol Name
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3
ALKBH4 alkB, alkylation repair homolog 4 (E. coli)
APH1B APH1B gamma secretase subunit
ARG1 arginase 1
ARMCX4 armadillo repeat containing, X-linked 4
ASAP1-IT1 ASAP1 intronic transcript 1
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
BGLAP bone gamma-carboxyglutamate (gla) protein
BMP15 bone morphogenetic protein 15
C8ORF44 chromosome 8 open reading frame 44
CCDC85C coiled-coil domain containing 85C
CDA cytidine deaminase
CEP295 centrosomal protein 295kDa
CEP97 centrosomal protein 97kDa
CHMP6 charged multivesicular body protein 6
CLIP2 CAP-GLY domain containing linker protein 2
CRELD1 cysteine-rich with EGF-like domains 1
DNAL4 dynein, axonemal, light chain 4
DNM3 dynamin 3
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1
EFNA4 ephrin-A4
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
F13A1 coagulation factor XIII, A1 polypeptide
FAM131A family with sequence similarity 131, member A
FBXW4P1 F-box and WD repeat domain containing 4 pseudogene 1
FKBP9 FK506 binding protein 9, 63 kDa
FOXO4 forkhead box O4
FZD6 frizzled class receptor 6
GAS2 growth arrest-specific 2
GK3P glycerol kinase 3 pseudogene
GPRIN2 G protein regulated inducer of neurite outgrowth 2
GSTT1 glutathione S-transferase theta 1
HAAO 3-hydroxyanthranilate 3,4-dioxygenase
HOXC8 homeobox C8
HSPA1L heat shock 70kDa protein 1-like
ICAM4 intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)
IDI2-AS1 IDI2 antisense RNA 1
INCENP inner centromere protein antigens 135/155kDa
INF2 inverted formin, FH2 and WH2 domain containing
ISOC1 isochorismatase domain containing 1
JMJD4 jumonji domain containing 4
KIAA0753 KIAA0753
LTBP3 latent transforming growth factor beta binding protein 3
LZTS3 leucine zipper, putative tumor suppressor family member 3
MAB21L1 mab-21-like 1 (C. elegans)
MFSD11 major facilitator superfamily domain containing 11
MINOS1P1 mitochondrial inner membrane organizing system 1 pseudogene 1
MOCS3 molybdenum cofactor synthesis 3
MVP major vault protein
MYOZ3 myozenin 3
NIPAL2 NIPA-like domain containing 2
NNAT neuronatin
NOL10 nucleolar protein 10
NR1H3 nuclear receptor subfamily 1, group H, member 3
NUDT18 nudix (nucleoside diphosphate linked moiety X)-type motif 18
OLAH oleoyl-ACP hydrolase
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
PADI2 peptidyl arginine deiminase, type II
PARP12 poly (ADP-ribose) polymerase family, member 12
PCDHGB5 protocadherin gamma subfamily B, 5
PDE6H phosphodiesterase 6H, cGMP-specific, cone, gamma
PIAS3 protein inhibitor of activated STAT, 3
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PLTP phospholipid transfer protein
PREX2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
PRKCZ protein kinase C, zeta
PRR7 proline rich 7 (synaptic)
PYCRL pyrroline-5-carboxylate reductase-like
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RRAGB Ras-related GTP binding B
SALL2 spalt-like transcription factor 2
SERINC5 serine incorporator 5
SGMS1 sphingomyelin synthase 1
SIRAL2 SIR2 antiphage like 2
SLC12A5 solute carrier family 12 (potassium/chloride transporter), member 5
SLC12A9 solute carrier family 12, member 9
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SPATA2L spermatogenesis associated 2-like
SPR sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase)
STAG3L4 stromal antigen 3-like 4 (pseudogene)
STARD3 StAR-related lipid transfer (START) domain containing 3
STX1A syntaxin 1A (brain)
TBL1Y transducin (beta)-like 1, Y-linked
TCEB3B transcription elongation factor B polypeptide 3B (elongin A2)
TM7SF3 transmembrane 7 superfamily member 3
TMEM209 transmembrane protein 209
UAP1L1 UDP-N-acetylglucosamine pyrophosphorylase 1 like 1
UPB1 ureidopropionase, beta
USP6NL USP6 N-terminal like
ZC3H3 zinc finger CCCH-type containing 3
ZNF225 zinc finger protein 225
ZNF492 zinc finger protein 492
ZNF778 zinc finger protein 778