iopromide Gene Set

Dataset	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures
Category	transcriptomics
Type	small molecule perturbation
Description	A dicarboxylic acid diamide that consists of N-methylisophthalamide bearing three iodo substituents at positions 2, 4 and 6, a methoxyacetyl substituent at position 5 and two 2,3-dihydroxypropyl groups attached to the amide nitrogens. A water soluble x-ray contrast agent for intravascular administration. (Chemical Entities of Biological Interest Ontology, CHEBI_63578)
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Genes

10 genes differentially expressed following the iopromide small molecule perturbation from the LINCS L1000 CMAP Chemical Perturbation Consensus Signatures dataset.

increased expression

Symbol	Name	Standardized Value
STXBP1	syntaxin binding protein 1	3.99847
IDH3B	isocitrate dehydrogenase 3 (NAD+) beta	3.26402

decreased expression

Symbol	Name	Standardized Value
HMG20B	high mobility group 20B	-4.87477
NFKBIB	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta	-4.8577
CASP10	caspase 10, apoptosis-related cysteine peptidase	-4.81545
ID4	inhibitor of DNA binding 4, dominant negative helix-loop-helix protein	-3.40191
PRDM13	PR domain containing 13	-3.397
CT62	cancer/testis antigen 62	-3.09372
HNF4G	hepatocyte nuclear factor 4, gamma	-3.06269
CDC42	cell division cycle 42	-3.0177