ioversol-3026 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

192 genes differentially expressed following the ioversol-3026 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABHD6 abhydrolase domain containing 6
ALDH1L1 aldehyde dehydrogenase 1 family, member L1
ARHGAP26 Rho GTPase activating protein 26
B3GAT1 beta-1,3-glucuronyltransferase 1
BDNF brain-derived neurotrophic factor
BFSP1 beaded filament structural protein 1, filensin
C6ORF10 chromosome 6 open reading frame 10
CCDC134 coiled-coil domain containing 134
CCDC70 coiled-coil domain containing 70
CD7 CD7 molecule
CDC14B cell division cycle 14B
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CHRNB3 cholinergic receptor, nicotinic, beta 3 (neuronal)
CIB2 calcium and integrin binding family member 2
CLTC clathrin, heavy chain (Hc)
COL10A1 collagen, type X, alpha 1
CRH corticotropin releasing hormone
CSPG4 chondroitin sulfate proteoglycan 4
CXCL3 chemokine (C-X-C motif) ligand 3
DCLK2 doublecortin-like kinase 2
DDAH1 dimethylarginine dimethylaminohydrolase 1
DDO D-aspartate oxidase
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DISC1 disrupted in schizophrenia 1
DKFZP434L187 uncharacterized LOC26082
DNAH3 dynein, axonemal, heavy chain 3
EGLN3 egl-9 family hypoxia-inducible factor 3
EPB41 erythrocyte membrane protein band 4.1
EYA3 EYA transcriptional coactivator and phosphatase 3
FBXO40 F-box protein 40
FCN1 ficolin (collagen/fibrinogen domain containing) 1
FRMD8 FERM domain containing 8
FUT3 fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group)
GABRA5 gamma-aminobutyric acid (GABA) A receptor, alpha 5
GAS1 growth arrest-specific 1
GFER growth factor, augmenter of liver regeneration
GHRH growth hormone releasing hormone
GLI2 GLI family zinc finger 2
GLP1R glucagon-like peptide 1 receptor
GPX7 glutathione peroxidase 7
GRHL2 grainyhead-like 2 (Drosophila)
HIST1H2BO histone cluster 1, H2bo
HOXA3 homeobox A3
HOXD3 homeobox D3
IFNA6 interferon, alpha 6
IL17RB interleukin 17 receptor B
IL33R interleukin 33 receptor
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2
KCNC1 potassium channel, voltage gated Shaw related subfamily C, member 1
KCNIP2 Kv channel interacting protein 2
KCNJ3 potassium channel, inwardly rectifying subfamily J, member 3
KDSR 3-ketodihydrosphingosine reductase
KRT17 keratin 17, type I
KRT81 keratin 81, type II
LMAN2 lectin, mannose-binding 2
LMF1 lipase maturation factor 1
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
MCAM melanoma cell adhesion molecule
MED25 mediator complex subunit 25
MYH11 myosin, heavy chain 11, smooth muscle
NMUR1 neuromedin U receptor 1
PCDHB17P protocadherin beta 17 pseudogene
PDE11A phosphodiesterase 11A
PHF7 PHD finger protein 7
PI4K2A phosphatidylinositol 4-kinase type 2 alpha
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PLEKHS1 pleckstrin homology domain containing, family S member 1
PLN phospholamban
PPP1R3A protein phosphatase 1, regulatory subunit 3A
PPP2R5B protein phosphatase 2, regulatory subunit B', beta
PTPRM protein tyrosine phosphatase, receptor type, M
PVR poliovirus receptor
RANBP3 RAN binding protein 3
RARA retinoic acid receptor, alpha
RBM12B-AS1 RBM12B antisense RNA 1
ROBO3 roundabout, axon guidance receptor, homolog 3 (Drosophila)
RPL10L ribosomal protein L10-like
SEMA6A sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
SEZ6L seizure related 6 homolog (mouse)-like
SH2D1A SH2 domain containing 1A
SLC12A5 solute carrier family 12 (potassium/chloride transporter), member 5
SLC22A7 solute carrier family 22 (organic anion transporter), member 7
SLC34A1 solute carrier family 34 (type II sodium/phosphate cotransporter), member 1
SLC37A1 solute carrier family 37 (glucose-6-phosphate transporter), member 1
SLMO1 slowmo homolog 1 (Drosophila)
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1
SRPK3 SRSF protein kinase 3
TBX5 T-box 5
TIAM1 T-cell lymphoma invasion and metastasis 1
TMC7 transmembrane channel-like 7
TMPRSS4 transmembrane protease, serine 4
TNP2 transition protein 2 (during histone to protamine replacement)
WISP3 WNT1 inducible signaling pathway protein 3
ZNF337 zinc finger protein 337

decreased expression

Symbol Name
ABCC6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6
ACPP acid phosphatase, prostate
ACVR2A activin A receptor, type IIA
ADTRP androgen-dependent TFPI-regulating protein
ALDOAP2 aldolase A, fructose-bisphosphate pseudogene 2
APOBEC2 apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26
AXIN1 axin 1
BBS1 Bardet-Biedl syndrome 1
BCAR3 breast cancer anti-estrogen resistance 3
BTBD18 BTB (POZ) domain containing 18
C11ORF30 chromosome 11 open reading frame 30
C8A complement component 8, alpha polypeptide
CA5BP1 carbonic anhydrase VB pseudogene 1
CCDC186 coiled-coil domain containing 186
CFP complement factor properdin
CHMP6 charged multivesicular body protein 6
CHPF chondroitin polymerizing factor
CLGN calmegin
CXORF56 chromosome X open reading frame 56
CYP2W1 cytochrome P450, family 2, subfamily W, polypeptide 1
DNAL4 dynein, axonemal, light chain 4
DTX2 deltex 2, E3 ubiquitin ligase
ECSIT ECSIT signalling integrator
EEF1A2 eukaryotic translation elongation factor 1 alpha 2
ERAL1 Era-like 12S mitochondrial rRNA chaperone 1
EXD3 exonuclease 3'-5' domain containing 3
FKBPL FK506 binding protein like
FOXD1 forkhead box D1
FRS3 fibroblast growth factor receptor substrate 3
FUZ fuzzy planar cell polarity protein
GABRA4 gamma-aminobutyric acid (GABA) A receptor, alpha 4
GBP2 guanylate binding protein 2, interferon-inducible
GDAP1 ganglioside induced differentiation associated protein 1
HIST1H1B histone cluster 1, H1b
HIST1H3G histone cluster 1, H3g
HOXB9 homeobox B9
IBSP integrin-binding sialoprotein
ICAM4 intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)
IFT140 intraflagellar transport 140
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IL18 interleukin 18
INCENP inner centromere protein antigens 135/155kDa
KHDRBS2 KH domain containing, RNA binding, signal transduction associated 2
KHDRBS3 KH domain containing, RNA binding, signal transduction associated 3
KIAA0753 KIAA0753
KIAA1107 KIAA1107
KLHL36 kelch-like family member 36
LIN7A lin-7 homolog A (C. elegans)
LRRC20 leucine rich repeat containing 20
LRRK1 leucine-rich repeat kinase 1
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
LTBP2 latent transforming growth factor beta binding protein 2
METRN meteorin, glial cell differentiation regulator
MICB MHC class I polypeptide-related sequence B
MPZ myelin protein zero
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
NCKAP1L NCK-associated protein 1-like
NDE1 nudE neurodevelopment protein 1
NME8 NME/NM23 family member 8
PARP16 poly (ADP-ribose) polymerase family, member 16
PDE12 phosphodiesterase 12
PDGFD platelet derived growth factor D
PLS1 plastin 1
PRSS21 protease, serine, 21 (testisin)
RAB17 RAB17, member RAS oncogene family
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1
RGS13 regulator of G-protein signaling 13
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
SALL2 spalt-like transcription factor 2
SCG5 secretogranin V
SERINC5 serine incorporator 5
SHPK sedoheptulokinase
SLC17A2 solute carrier family 17, member 2
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
STAT5A signal transducer and activator of transcription 5A
STK16 serine/threonine kinase 16
TBKBP1 TBK1 binding protein 1
TBXAS1 thromboxane A synthase 1 (platelet)
THBS3 thrombospondin 3
TMEM209 transmembrane protein 209
TOM1 target of myb1 (chicken)
TRIM68 tripartite motif containing 68
TRIM9 tripartite motif containing 9
UAP1L1 UDP-N-acetylglucosamine pyrophosphorylase 1 like 1
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
WDR25 WD repeat domain 25
YOD1 YOD1 deubiquitinase
ZBTB48 zinc finger and BTB domain containing 48
ZBTB6 zinc finger and BTB domain containing 6
ZNF428 zinc finger protein 428
ZNF668 zinc finger protein 668
ZNF671 zinc finger protein 671
ZNF749 zinc finger protein 749
ZNF768 zinc finger protein 768