| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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194 genes differentially expressed following the ioversol-6726 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACVR1B | activin A receptor, type IB |
| AIF1 | allograft inflammatory factor 1 |
| ALOX12B | arachidonate 12-lipoxygenase, 12R type |
| ANGPTL2 | angiopoietin-like 2 |
| ANKRD7 | ankyrin repeat domain 7 |
| ARTN | artemin |
| BTG2 | BTG family, member 2 |
| BTRC | beta-transducin repeat containing E3 ubiquitin protein ligase |
| C10ORF12 | chromosome 10 open reading frame 12 |
| C11ORF30 | chromosome 11 open reading frame 30 |
| C8A | complement component 8, alpha polypeptide |
| CABP1 | calcium binding protein 1 |
| CCDC102B | coiled-coil domain containing 102B |
| CD177 | CD177 molecule |
| CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) |
| CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha |
| CEP68 | centrosomal protein 68kDa |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) |
| CNR2 | cannabinoid receptor 2 (macrophage) |
| CTNND2 | catenin (cadherin-associated protein), delta 2 |
| CYBB | cytochrome b-245, beta polypeptide |
| DCN | decorin |
| DMP1 | dentin matrix acidic phosphoprotein 1 |
| DSTYK | dual serine/threonine and tyrosine protein kinase |
| E2F4 | E2F transcription factor 4, p107/p130-binding |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 |
| EFCAB6 | EF-hand calcium binding domain 6 |
| ENOX1 | ecto-NOX disulfide-thiol exchanger 1 |
| ETV1 | ets variant 1 |
| EYA4 | EYA transcriptional coactivator and phosphatase 4 |
| FAM182A | family with sequence similarity 182, member A |
| FGB | fibrinogen beta chain |
| FGF1 | fibroblast growth factor 1 (acidic) |
| FKBP8 | FK506 binding protein 8, 38kDa |
| FMO3 | flavin containing monooxygenase 3 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide |
| GPR68 | G protein-coupled receptor 68 |
| GPR85 | G protein-coupled receptor 85 |
| GRIA3 | glutamate receptor, ionotropic, AMPA 3 |
| HIC2 | hypermethylated in cancer 2 |
| HRG | histidine-rich glycoprotein |
| IL11 | interleukin 11 |
| INSR | insulin receptor |
| INTS1 | integrator complex subunit 1 |
| ITGAX | integrin, alpha X (complement component 3 receptor 4 subunit) |
| KCNJ5 | potassium channel, inwardly rectifying subfamily J, member 5 |
| KIAA1467 | KIAA1467 |
| LAMB4 | laminin, beta 4 |
| LLGL1 | lethal giant larvae homolog 1 (Drosophila) |
| MAG | myelin associated glycoprotein |
| MAPK10 | mitogen-activated protein kinase 10 |
| MEG3 | maternally expressed 3 (non-protein coding) |
| MRPL20 | mitochondrial ribosomal protein L20 |
| MRPS18C | mitochondrial ribosomal protein S18C |
| MTHFR | methylenetetrahydrofolate reductase (NAD(P)H) |
| MYO9B | myosin IXB |
| NMUR1 | neuromedin U receptor 1 |
| NPC1 | Niemann-Pick disease, type C1 |
| NRG1 | neuregulin 1 |
| NTRK2 | neurotrophic tyrosine kinase, receptor, type 2 |
| OTOF | otoferlin |
| PALM | paralemmin |
| PARVA | parvin, alpha |
| PAX5 | paired box 5 |
| PCDHGA10 | protocadherin gamma subfamily A, 10 |
| PDE5A | phosphodiesterase 5A, cGMP-specific |
| PPARA | peroxisome proliferator-activated receptor alpha |
| PPP3R1 | protein phosphatase 3, regulatory subunit B, alpha |
| PPP4R4 | protein phosphatase 4, regulatory subunit 4 |
| RAB11B | RAB11B, member RAS oncogene family |
| RAB3D | RAB3D, member RAS oncogene family |
| RHOT2 | ras homolog family member T2 |
| RUNX1 | runt-related transcription factor 1 |
| SCAND2P | SCAN domain containing 2 pseudogene |
| SCARB1 | scavenger receptor class B, member 1 |
| SENP7 | SUMO1/sentrin specific peptidase 7 |
| SLC34A2 | solute carrier family 34 (type II sodium/phosphate cotransporter), member 2 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) |
| SRSF7 | serine/arginine-rich splicing factor 7 |
| ST3GAL4 | ST3 beta-galactoside alpha-2,3-sialyltransferase 4 |
| TBXA2R | thromboxane A2 receptor |
| TCF12 | transcription factor 12 |
| TCF4 | transcription factor 4 |
| TGFA | transforming growth factor, alpha |
| TLN2 | talin 2 |
| TMEM140 | transmembrane protein 140 |
| TRIM3 | tripartite motif containing 3 |
| TRPC1 | transient receptor potential cation channel, subfamily C, member 1 |
| TRPM3 | transient receptor potential cation channel, subfamily M, member 3 |
| UBE2B | ubiquitin-conjugating enzyme E2B |
| ZBED4 | zinc finger, BED-type containing 4 |
| ZFAND5 | zinc finger, AN1-type domain 5 |
| ZNF268 | zinc finger protein 268 |
| ZNF407 | zinc finger protein 407 |
| ZNF609 | zinc finger protein 609 |
| ZNF76 | zinc finger protein 76 |
| ZNF768 | zinc finger protein 768 |
| ZNF783 | zinc finger family member 783 |
| ZNF93 | zinc finger protein 93 |
| Symbol | Name |
|---|---|
| ACVR2B | activin A receptor, type IIB |
| AGMAT | agmatine ureohydrolase (agmatinase) |
| APOC4 | apolipoprotein C-IV |
| ARHGEF16 | Rho guanine nucleotide exchange factor (GEF) 16 |
| ARMCX4 | armadillo repeat containing, X-linked 4 |
| ASPSCR1 | alveolar soft part sarcoma chromosome region, candidate 1 |
| ATAD5 | ATPase family, AAA domain containing 5 |
| C11ORF63 | chromosome 11 open reading frame 63 |
| C1QTNF9B-AS1 | C1QTNF9B antisense RNA 1 |
| C22ORF29 | chromosome 22 open reading frame 29 |
| C5ORF45 | chromosome 5 open reading frame 45 |
| CCDC106 | coiled-coil domain containing 106 |
| CCDC85C | coiled-coil domain containing 85C |
| CCNT1 | cyclin T1 |
| CDK3 | cyclin-dependent kinase 3 |
| CEP162 | centrosomal protein 162kDa |
| CHMP6 | charged multivesicular body protein 6 |
| CIDEC | cell death-inducing DFFA-like effector c |
| CISH | cytokine inducible SH2-containing protein |
| CNN1 | calponin 1, basic, smooth muscle |
| CPZ | carboxypeptidase Z |
| CRMP1 | collapsin response mediator protein 1 |
| CSF1R | colony stimulating factor 1 receptor |
| CYP7B1 | cytochrome P450, family 7, subfamily B, polypeptide 1 |
| DCSTAMP | dendrocyte expressed seven transmembrane protein |
| DEPTOR | DEP domain containing MTOR-interacting protein |
| EXD3 | exonuclease 3'-5' domain containing 3 |
| FHOD1 | formin homology 2 domain containing 1 |
| FMO4 | flavin containing monooxygenase 4 |
| FOXRED2 | FAD-dependent oxidoreductase domain containing 2 |
| FRMD8 | FERM domain containing 8 |
| GATA4 | GATA binding protein 4 |
| HDAC11 | histone deacetylase 11 |
| HIST1H2AI | histone cluster 1, H2ai |
| HIST1H2BO | histone cluster 1, H2bo |
| HNRNPA3P1 | heterogeneous nuclear ribonucleoprotein A3 pseudogene 1 |
| HOOK1 | hook microtubule-tethering protein 1 |
| HSPB6 | heat shock protein, alpha-crystallin-related, B6 |
| ICOS | inducible T-cell co-stimulator |
| INADL | InaD-like (Drosophila) |
| IREB2 | iron-responsive element binding protein 2 |
| KCNN1 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1 |
| KIRREL | kin of IRRE like (Drosophila) |
| KLHL36 | kelch-like family member 36 |
| KRT31 | keratin 31, type I |
| KRT34 | keratin 34, type I |
| KRT6A | keratin 6A, type II |
| LAMC3 | laminin, gamma 3 |
| LHPP | phospholysine phosphohistidine inorganic pyrophosphate phosphatase |
| LIME1 | Lck interacting transmembrane adaptor 1 |
| LINC00115 | long intergenic non-protein coding RNA 115 |
| LMO7 | LIM domain 7 |
| LOC257152 | uncharacterized LOC257152 |
| LRRK1 | leucine-rich repeat kinase 1 |
| MAP3K7CL | MAP3K7 C-terminal like |
| ME3 | malic enzyme 3, NADP(+)-dependent, mitochondrial |
| METTL16 | methyltransferase like 16 |
| MILR1 | mast cell immunoglobulin-like receptor 1 |
| MPP3 | membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3) |
| MYH15 | myosin, heavy chain 15 |
| NEK11 | NIMA-related kinase 11 |
| NPIPB15 | nuclear pore complex interacting protein family, member B15 |
| NPM3 | nucleophosmin/nucleoplasmin 3 |
| OBSCN | obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF |
| PAIP2B | poly(A) binding protein interacting protein 2B |
| PALMD | palmdelphin |
| PCDH12 | protocadherin 12 |
| PCDHA5 | protocadherin alpha 5 |
| PIGZ | phosphatidylinositol glycan anchor biosynthesis, class Z |
| PLD3 | phospholipase D family, member 3 |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C |
| PRAMEF10 | PRAME family member 10 |
| PRPH | peripherin |
| PSKH1 | protein serine kinase H1 |
| QSER1 | glutamine and serine rich 1 |
| RAPGEFL1 | Rap guanine nucleotide exchange factor (GEF)-like 1 |
| RPGRIP1L | RPGRIP1-like |
| RPH3AL | rabphilin 3A-like (without C2 domains) |
| RPL13P5 | ribosomal protein L13 pseudogene 5 |
| SCN1B | sodium channel, voltage gated, type I beta subunit |
| SLC16A6 | solute carrier family 16, member 6 |
| SLC22A1 | solute carrier family 22 (organic cation transporter), member 1 |
| SNTG1 | syntrophin, gamma 1 |
| SOX12 | SRY (sex determining region Y)-box 12 |
| SPRYD7 | SPRY domain containing 7 |
| STON1 | stonin 1 |
| TBXAS1 | thromboxane A synthase 1 (platelet) |
| TESPA1 | thymocyte expressed, positive selection associated 1 |
| TNFSF9 | tumor necrosis factor (ligand) superfamily, member 9 |
| TUBA4B | tubulin, alpha 4b |
| USP19 | ubiquitin specific peptidase 19 |
| VGF | VGF nerve growth factor inducible |
| ZNF385D | zinc finger protein 385D |
| ZNHIT2 | zinc finger, HIT-type containing 2 |