| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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191 genes differentially expressed following the ioxaglic acid-2966 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACADSB | acyl-CoA dehydrogenase, short/branched chain |
| ADAM22 | ADAM metallopeptidase domain 22 |
| ADGRG2 | adhesion G protein-coupled receptor G2 |
| AP5S1 | adaptor-related protein complex 5, sigma 1 subunit |
| APBB1IP | amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein |
| ARHGDIA | Rho GDP dissociation inhibitor (GDI) alpha |
| ARMCX4 | armadillo repeat containing, X-linked 4 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide |
| BAHCC1 | BAH domain and coiled-coil containing 1 |
| BIN1 | bridging integrator 1 |
| C17ORF53 | chromosome 17 open reading frame 53 |
| CAMSAP1 | calmodulin regulated spectrin-associated protein 1 |
| CCDC170 | coiled-coil domain containing 170 |
| CCDC85B | coiled-coil domain containing 85B |
| CCDC9 | coiled-coil domain containing 9 |
| CD70 | CD70 molecule |
| CDC14B | cell division cycle 14B |
| CFAP45 | cilia and flagella associated protein 45 |
| COL4A2 | collagen, type IV, alpha 2 |
| CTNND2 | catenin (cadherin-associated protein), delta 2 |
| DDR1-AS1 | DDR1 antisense RNA 1 (head to head) |
| DDX31 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 |
| EFNA5 | ephrin-A5 |
| ERMAP | erythroblast membrane-associated protein (Scianna blood group) |
| EXD3 | exonuclease 3'-5' domain containing 3 |
| EXPH5 | exophilin 5 |
| F12 | coagulation factor XII (Hageman factor) |
| FAM127A | family with sequence similarity 127, member A |
| FSCN1 | fascin actin-bundling protein 1 |
| GAD2 | glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) |
| GAS8 | growth arrest-specific 8 |
| GPRIN2 | G protein regulated inducer of neurite outgrowth 2 |
| GSPT1 | G1 to S phase transition 1 |
| HIC2 | hypermethylated in cancer 2 |
| HIST1H1D | histone cluster 1, H1d |
| HTRA2 | HtrA serine peptidase 2 |
| IMPG2 | interphotoreceptor matrix proteoglycan 2 |
| INPP5J | inositol polyphosphate-5-phosphatase J |
| KHSRP | KH-type splicing regulatory protein |
| KIF3C | kinesin family member 3C |
| KLHL25 | kelch-like family member 25 |
| LAD1 | ladinin 1 |
| LEF1 | lymphoid enhancer-binding factor 1 |
| MAST2 | microtubule associated serine/threonine kinase 2 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 |
| MID1 | midline 1 |
| MINK1 | misshapen-like kinase 1 |
| MKL1 | megakaryoblastic leukemia (translocation) 1 |
| MLH3 | mutL homolog 3 |
| MOGS | mannosyl-oligosaccharide glucosidase |
| MRAS | muscle RAS oncogene homolog |
| MREG | melanoregulin |
| MUL1 | mitochondrial E3 ubiquitin protein ligase 1 |
| MZF1 | myeloid zinc finger 1 |
| NR2C1 | nuclear receptor subfamily 2, group C, member 1 |
| P2RY4 | pyrimidinergic receptor P2Y, G-protein coupled, 4 |
| PADI2 | peptidyl arginine deiminase, type II |
| PDGFB | platelet-derived growth factor beta polypeptide |
| PDLIM2 | PDZ and LIM domain 2 (mystique) |
| PHF1 | PHD finger protein 1 |
| PHF3 | PHD finger protein 3 |
| PPIL2 | peptidylprolyl isomerase (cyclophilin)-like 2 |
| PPP2R2B | protein phosphatase 2, regulatory subunit B, beta |
| PRKCA | protein kinase C, alpha |
| PTAFR | platelet-activating factor receptor |
| RET | ret proto-oncogene |
| RGS12 | regulator of G-protein signaling 12 |
| RGS19 | regulator of G-protein signaling 19 |
| ROM1 | retinal outer segment membrane protein 1 |
| RPL13P5 | ribosomal protein L13 pseudogene 5 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A |
| SLN | sarcolipin |
| SMG7 | SMG7 nonsense mediated mRNA decay factor |
| SRSF7 | serine/arginine-rich splicing factor 7 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) |
| ST3GAL4 | ST3 beta-galactoside alpha-2,3-sialyltransferase 4 |
| STK11 | serine/threonine kinase 11 |
| TBRG4 | transforming growth factor beta regulator 4 |
| TBXA2R | thromboxane A2 receptor |
| TEAD4 | TEA domain family member 4 |
| TMCC1 | transmembrane and coiled-coil domain family 1 |
| TMEM2 | transmembrane protein 2 |
| TNFRSF8 | tumor necrosis factor receptor superfamily, member 8 |
| TPM1 | tropomyosin 1 (alpha) |
| TRMT61A | tRNA methyltransferase 61A |
| TUBA4B | tubulin, alpha 4b |
| UBQLN4 | ubiquilin 4 |
| UBTF | upstream binding transcription factor, RNA polymerase I |
| UPF3A | UPF3 regulator of nonsense transcripts homolog A (yeast) |
| USP46 | ubiquitin specific peptidase 46 |
| WWTR1 | WW domain containing transcription regulator 1 |
| ZFYVE9 | zinc finger, FYVE domain containing 9 |
| ZNF235 | zinc finger protein 235 |
| ZNF34 | zinc finger protein 34 |
| ZNF609 | zinc finger protein 609 |
| ZNF710 | zinc finger protein 710 |
| ZXDB | zinc finger, X-linked, duplicated B |
| Symbol | Name |
|---|---|
| AACS | acetoacetyl-CoA synthetase |
| AMIGO2 | adhesion molecule with Ig-like domain 2 |
| APPL2 | adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2 |
| ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 |
| ARID3B | AT rich interactive domain 3B (BRIGHT-like) |
| ARID5A | AT rich interactive domain 5A (MRF1-like) |
| C17ORF75 | chromosome 17 open reading frame 75 |
| CBLL1 | Cbl proto-oncogene-like 1, E3 ubiquitin protein ligase |
| CD9 | CD9 molecule |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
| CDKN2D | cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) |
| CGREF1 | cell growth regulator with EF-hand domain 1 |
| CPSF7 | cleavage and polyadenylation specific factor 7, 59kDa |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 |
| DNMBP | dynamin binding protein |
| DOCK4 | dedicator of cytokinesis 4 |
| DYM | dymeclin |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 |
| EGR3 | early growth response 3 |
| EMILIN2 | elastin microfibril interfacer 2 |
| ERF | Ets2 repressor factor |
| ETV4 | ets variant 4 |
| FAM188A | family with sequence similarity 188, member A |
| FAM192A | family with sequence similarity 192, member A |
| FBRS | fibrosin |
| FKBPL | FK506 binding protein like |
| GBP2 | guanylate binding protein 2, interferon-inducible |
| GCNT1 | glucosaminyl (N-acetyl) transferase 1, core 2 |
| GMPPB | GDP-mannose pyrophosphorylase B |
| GNG7 | guanine nucleotide binding protein (G protein), gamma 7 |
| GPALPP1 | GPALPP motifs containing 1 |
| GRAMD1B | GRAM domain containing 1B |
| GSTM2 | glutathione S-transferase mu 2 (muscle) |
| HDAC4 | histone deacetylase 4 |
| HIST1H2BN | histone cluster 1, H2bn |
| HP | haptoglobin |
| HS1BP3 | HCLS1 binding protein 3 |
| IER3 | immediate early response 3 |
| IFI6 | interferon, alpha-inducible protein 6 |
| IL4R | interleukin 4 receptor |
| ISG20 | interferon stimulated exonuclease gene 20kDa |
| ITGAX | integrin, alpha X (complement component 3 receptor 4 subunit) |
| JADE3 | jade family PHD finger 3 |
| KAT2A | K(lysine) acetyltransferase 2A |
| KIAA0754 | KIAA0754 |
| KIF1B | kinesin family member 1B |
| MAGEB2 | melanoma antigen family B2 |
| MANSC1 | MANSC domain containing 1 |
| MED9 | mediator complex subunit 9 |
| MST1 | macrophage stimulating 1 |
| MVD | mevalonate (diphospho) decarboxylase |
| MX1 | MX dynamin-like GTPase 1 |
| NT5E | 5'-nucleotidase, ecto (CD73) |
| OLR1 | oxidized low density lipoprotein (lectin-like) receptor 1 |
| PAQR4 | progestin and adipoQ receptor family member IV |
| PIM2 | Pim-2 proto-oncogene, serine/threonine kinase |
| PKIG | protein kinase (cAMP-dependent, catalytic) inhibitor gamma |
| PLAG1 | pleiomorphic adenoma gene 1 |
| PMCH | pro-melanin-concentrating hormone |
| PNMA1 | paraneoplastic Ma antigen 1 |
| PNOC | prepronociceptin |
| POMT1 | protein-O-mannosyltransferase 1 |
| POMZP3 | POM121 and ZP3 fusion |
| PPP3CC | protein phosphatase 3, catalytic subunit, gamma isozyme |
| PRAF2 | PRA1 domain family, member 2 |
| PRKX | protein kinase, X-linked |
| PTCD2 | pentatricopeptide repeat domain 2 |
| PTH2R | parathyroid hormone 2 receptor |
| RPAIN | RPA interacting protein |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| RPL23AP7 | ribosomal protein L23a pseudogene 7 |
| RUSC2 | RUN and SH3 domain containing 2 |
| SGK1 | serum/glucocorticoid regulated kinase 1 |
| SLC16A4 | solute carrier family 16, member 4 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 |
| SP1 | Sp1 transcription factor |
| STAG3 | stromal antigen 3 |
| STBD1 | starch binding domain 1 |
| STON1 | stonin 1 |
| STRN | striatin, calmodulin binding protein |
| SULT1A2 | sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2 |
| TCEA2 | transcription elongation factor A (SII), 2 |
| TCTA | T-cell leukemia translocation altered |
| TMEM184C | transmembrane protein 184C |
| TMEM254 | transmembrane protein 254 |
| TRPS1 | trichorhinophalangeal syndrome I |
| TUBB2A | tubulin, beta 2A class IIa |
| UPP1 | uridine phosphorylase 1 |
| USB1 | U6 snRNA biogenesis 1 |
| WDR60 | WD repeat domain 60 |
| ZNF212 | zinc finger protein 212 |
| ZNF230 | zinc finger protein 230 |
| ZNF32 | zinc finger protein 32 |
| ZNF529 | zinc finger protein 529 |
