iproniazid-2288 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the iproniazid-2288 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A4GNT alpha-1,4-N-acetylglucosaminyltransferase
ABCB9 ATP-binding cassette, sub-family B (MDR/TAP), member 9
ACPP acid phosphatase, prostate
ADAM29 ADAM metallopeptidase domain 29
ADCK2 aarF domain containing kinase 2
ADGRA2 adhesion G protein-coupled receptor A2
AIM2 absent in melanoma 2
APOE apolipoprotein E
ATP10B ATPase, class V, type 10B
ATP1A2 ATPase, Na+/K+ transporting, alpha 2 polypeptide
ATP2B2 ATPase, Ca++ transporting, plasma membrane 2
BAAT bile acid CoA:amino acid N-acyltransferase
BAZ2B bromodomain adjacent to zinc finger domain, 2B
BCL2 B-cell CLL/lymphoma 2
BIRC7 baculoviral IAP repeat containing 7
C9ORF156 chromosome 9 open reading frame 156
CA3 carbonic anhydrase III
CAMK2B calcium/calmodulin-dependent protein kinase II beta
CCDC64 coiled-coil domain containing 64
CD36 CD36 molecule (thrombospondin receptor)
CD53 CD53 molecule
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1
CFLAR CASP8 and FADD-like apoptosis regulator
CLIC5 chloride intracellular channel 5
COL2A1 collagen, type II, alpha 1
COPG2IT1 COPG2 imprinted transcript 1 (non-protein coding)
CPQ carboxypeptidase Q
CREBBP CREB binding protein
CRISP2 cysteine-rich secretory protein 2
CROCCP3 ciliary rootlet coiled-coil, rootletin pseudogene 3
CRTC1 CREB regulated transcription coactivator 1
CSF1R colony stimulating factor 1 receptor
CUL7 cullin 7
CYP4F12 cytochrome P450, family 4, subfamily F, polypeptide 12
DNAJC4 DnaJ (Hsp40) homolog, subfamily C, member 4
ELL elongation factor RNA polymerase II
EXOC7 exocyst complex component 7
FGF17 fibroblast growth factor 17
FPR1 formyl peptide receptor 1
GPT glutamic-pyruvate transaminase (alanine aminotransferase)
GRM1 glutamate receptor, metabotropic 1
GUCA1B guanylate cyclase activator 1B (retina)
H2AFX H2A histone family, member X
HCFC1 host cell factor C1
HCN2 hyperpolarization activated cyclic nucleotide gated potassium channel 2
HFE hemochromatosis
HR hair growth associated
IFI27 interferon, alpha-inducible protein 27
IFNA14 interferon, alpha 14
IL2 interleukin 2
IL36G interleukin 36, gamma
IVL involucrin
KCNH6 potassium channel, voltage gated eag related subfamily H, member 6
KLF13 Kruppel-like factor 13
KLHL18 kelch-like family member 18
KLHL25 kelch-like family member 25
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MAS1 MAS1 proto-oncogene, G protein-coupled receptor
MEF2C myocyte enhancer factor 2C
MEGF6 multiple EGF-like-domains 6
MLANA melan-A
MMP25 matrix metallopeptidase 25
MNMIP1 manchette microtubule inner protein 1
MOBP myelin-associated oligodendrocyte basic protein
MOGAT2 monoacylglycerol O-acyltransferase 2
NBL1 neuroblastoma 1, DAN family BMP antagonist
NDRG2 NDRG family member 2
NPHP1 nephronophthisis 1 (juvenile)
NRL neural retina leucine zipper
PACS1 phosphofurin acidic cluster sorting protein 1
PALM paralemmin
PCDH12 protocadherin 12
PCSK6 proprotein convertase subtilisin/kexin type 6
PDE4B phosphodiesterase 4B, cAMP-specific
PER2 period circadian clock 2
PFKFB2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
PIP prolactin-induced protein
PPFIBP2 PTPRF interacting protein, binding protein 2 (liprin beta 2)
PRX periaxin
RCN1 reticulocalbin 1, EF-hand calcium binding domain
RHEB Ras homolog enriched in brain
RNF122 ring finger protein 122
RNF17 ring finger protein 17
SAYSD1 SAYSVFN motif domain containing 1
SCARA3 scavenger receptor class A, member 3
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
SNX13 sorting nexin 13
SRF serum response factor (c-fos serum response element-binding transcription factor)
SSX3 synovial sarcoma, X breakpoint 3
SYCE1L synaptonemal complex central element protein 1-like
TBXA2R thromboxane A2 receptor
TIMP3 TIMP metallopeptidase inhibitor 3
TLL1 tolloid-like 1
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TRPM2 transient receptor potential cation channel, subfamily M, member 2
USP2 ubiquitin specific peptidase 2
VPS53 vacuolar protein sorting 53 homolog (S. cerevisiae)
WDR55 WD repeat domain 55
ZNF528 zinc finger protein 528
ZNF646 zinc finger protein 646

decreased expression

Symbol Name
A1CF APOBEC1 complementation factor
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase
ADTRP androgen-dependent TFPI-regulating protein
ALPK1 alpha-kinase 1
AMT aminomethyltransferase
APOLD1 apolipoprotein L domain containing 1
ASIC1 acid sensing (proton gated) ion channel 1
B3GALT4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4
BAG4 BCL2-associated athanogene 4
BAHD1 bromo adjacent homology domain containing 1
BHLHE41 basic helix-loop-helix family, member e41
BRAF B-Raf proto-oncogene, serine/threonine kinase
C14ORF79 chromosome 14 open reading frame 79
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CCDC132 coiled-coil domain containing 132
CD34 CD34 molecule
CD82 CD82 molecule
CFAP44 cilia and flagella associated protein 44
CFAP45 cilia and flagella associated protein 45
CLDND1 claudin domain containing 1
CNN2 calponin 2
CNTN1 contactin 1
CUL9 cullin 9
CUZD1 CUB and zona pellucida-like domains 1
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
ELP6 elongator acetyltransferase complex subunit 6
EPHX2 epoxide hydrolase 2, cytoplasmic
ERCC4 excision repair cross-complementation group 4
ERMAP erythroblast membrane-associated protein (Scianna blood group)
ERN2 endoplasmic reticulum to nucleus signaling 2
FAM120C family with sequence similarity 120C
FAM131A family with sequence similarity 131, member A
FKBP10 FK506 binding protein 10, 65 kDa
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12
GATA4 GATA binding protein 4
GFI1 growth factor independent 1 transcription repressor
GINS4 GINS complex subunit 4 (Sld5 homolog)
GPR176 G protein-coupled receptor 176
GPR27 G protein-coupled receptor 27
GRB7 growth factor receptor-bound protein 7
GUSBP3 glucuronidase, beta pseudogene 3
HIST1H4F histone cluster 1, H4f
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HOXC4 homeobox C4
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
INHA inhibin, alpha
IQCG IQ motif containing G
KIAA0319L KIAA0319-like
KLRG1 killer cell lectin-like receptor subfamily G, member 1
LIN7A lin-7 homolog A (C. elegans)
LINC01587 long intergenic non-protein coding RNA 1587
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1
MAGEH1 melanoma antigen family H1
MED31 mediator complex subunit 31
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1
MMP3 matrix metallopeptidase 3
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)
PCDHA6 protocadherin alpha 6
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PLEKHO2 pleckstrin homology domain containing, family O member 2
PLEKHS1 pleckstrin homology domain containing, family S member 1
PPP2R3B protein phosphatase 2, regulatory subunit B'', beta
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
RCOR3 REST corepressor 3
S100A9 S100 calcium binding protein A9
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SETD8 SET domain containing (lysine methyltransferase) 8
SIX1 SIX homeobox 1
SLC16A6 solute carrier family 16, member 6
SLC29A3 solute carrier family 29 (equilibrative nucleoside transporter), member 3
SLC30A3 solute carrier family 30 (zinc transporter), member 3
SLC34A2 solute carrier family 34 (type II sodium/phosphate cotransporter), member 2
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TARP TCR gamma alternate reading frame protein
TBC1D2 TBC1 domain family, member 2
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1
TCHH trichohyalin
TLN1 talin 1
UBQLN4 ubiquilin 4
VEZT vezatin, adherens junctions transmembrane protein
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
YY2 YY2 transcription factor
ZBTB33 zinc finger and BTB domain containing 33
ZCWPW1 zinc finger, CW type with PWWP domain 1
ZDHHC18 zinc finger, DHHC-type containing 18
ZIM2 zinc finger, imprinted 2
ZNF136 zinc finger protein 136
ZNF37BP zinc finger protein 37B, pseudogene
ZNF428 zinc finger protein 428
ZNF652 zinc finger protein 652
ZNF747 zinc finger protein 747
ZNF76 zinc finger protein 76
ZNF778 zinc finger protein 778