| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the iproniazid-5458 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCA7 | ATP-binding cassette, sub-family A (ABC1), member 7 |
| ACVR1B | activin A receptor, type IB |
| ADGRG1 | adhesion G protein-coupled receptor G1 |
| ADORA1 | adenosine A1 receptor |
| AHNAK | AHNAK nucleoprotein |
| ALDOB | aldolase B, fructose-bisphosphate |
| ANKH | ANKH inorganic pyrophosphate transport regulator |
| APC | adenomatous polyposis coli |
| APOE | apolipoprotein E |
| APOH | apolipoprotein H (beta-2-glycoprotein I) |
| ATP10B | ATPase, class V, type 10B |
| B3GNT3 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 |
| BCL2A1 | BCL2-related protein A1 |
| C14ORF79 | chromosome 14 open reading frame 79 |
| C3ORF18 | chromosome 3 open reading frame 18 |
| CABP2 | calcium binding protein 2 |
| CACNA1D | calcium channel, voltage-dependent, L type, alpha 1D subunit |
| CCL5 | chemokine (C-C motif) ligand 5 |
| CDK14 | cyclin-dependent kinase 14 |
| CEP295 | centrosomal protein 295kDa |
| CLSTN2 | calsyntenin 2 |
| CNGB3 | cyclic nucleotide gated channel beta 3 |
| COX6A2 | cytochrome c oxidase subunit VIa polypeptide 2 |
| CTNS | cystinosin, lysosomal cystine transporter |
| CYP2D6 | cytochrome P450, family 2, subfamily D, polypeptide 6 |
| DCAKD | dephospho-CoA kinase domain containing |
| DNALI1 | dynein, axonemal, light intermediate chain 1 |
| DOCK5 | dedicator of cytokinesis 5 |
| DUSP26 | dual specificity phosphatase 26 (putative) |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| FBXO2 | F-box protein 2 |
| FEZ2 | fasciculation and elongation protein zeta 2 (zygin II) |
| FOXD2 | forkhead box D2 |
| GAS7 | growth arrest-specific 7 |
| GK | glycerol kinase |
| GK3P | glycerol kinase 3 pseudogene |
| GSK3A | glycogen synthase kinase 3 alpha |
| HDAC11 | histone deacetylase 11 |
| HDAC7 | histone deacetylase 7 |
| HIC2 | hypermethylated in cancer 2 |
| HIST1H4E | histone cluster 1, H4e |
| HMGN5 | high mobility group nucleosome binding domain 5 |
| HNF1B | HNF1 homeobox B |
| HPX | hemopexin |
| IGFBP3 | insulin-like growth factor binding protein 3 |
| IL17RC | interleukin 17 receptor C |
| ITGB4 | integrin, beta 4 |
| ITIH5 | inter-alpha-trypsin inhibitor heavy chain family, member 5 |
| JMJD4 | jumonji domain containing 4 |
| KLK13 | kallikrein-related peptidase 13 |
| LILRB3 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 |
| LLPH | LLP homolog, long-term synaptic facilitation (Aplysia) |
| MAOB | monoamine oxidase B |
| MIP | major intrinsic protein of lens fiber |
| MOG | myelin oligodendrocyte glycoprotein |
| MUC4 | mucin 4, cell surface associated |
| MYO7A | myosin VIIA |
| NDUFA2 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa |
| NF1 | neurofibromin 1 |
| NPR1 | natriuretic peptide receptor 1 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 |
| OTC | ornithine carbamoyltransferase |
| PARVA | parvin, alpha |
| PCDHGA8 | protocadherin gamma subfamily A, 8 |
| PCDHGC3 | protocadherin gamma subfamily C, 3 |
| PDE4DIP | phosphodiesterase 4D interacting protein |
| PIGR | polymeric immunoglobulin receptor |
| PPP4R4 | protein phosphatase 4, regulatory subunit 4 |
| PRKAR1B | protein kinase, cAMP-dependent, regulatory, type I, beta |
| PRY | PTPN13-like, Y-linked |
| PTMS | parathymosin |
| PTPN7 | protein tyrosine phosphatase, non-receptor type 7 |
| PTX3 | pentraxin 3, long |
| RGS5 | regulator of G-protein signaling 5 |
| RGS7 | regulator of G-protein signaling 7 |
| RORA | RAR-related orphan receptor A |
| RRBP1 | ribosome binding protein 1 |
| RUNDC3A | RUN domain containing 3A |
| SH3BP2 | SH3-domain binding protein 2 |
| SLAMF1 | signaling lymphocytic activation molecule family member 1 |
| SLC35E2 | solute carrier family 35, member E2 |
| SLC38A4 | solute carrier family 38, member 4 |
| SLC7A8 | solute carrier family 7 (amino acid transporter light chain, L system), member 8 |
| SLMO1 | slowmo homolog 1 (Drosophila) |
| SMR3B | submaxillary gland androgen regulated protein 3B |
| SPRY1 | sprouty homolog 1, antagonist of FGF signaling (Drosophila) |
| ST6GAL1 | ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 |
| TBC1D1 | TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1 |
| TBC1D22A | TBC1 domain family, member 22A |
| TICAM1 | toll-like receptor adaptor molecule 1 |
| TMEFF1 | transmembrane protein with EGF-like and two follistatin-like domains 1 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 |
| TNFRSF10C | tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain |
| TRIM21 | tripartite motif containing 21 |
| TSPAN9 | tetraspanin 9 |
| UGT2B15 | UDP glucuronosyltransferase 2 family, polypeptide B15 |
| VAC14 | Vac14 homolog (S. cerevisiae) |
| VPS13C | vacuolar protein sorting 13 homolog C (S. cerevisiae) |
| ZMAT4 | zinc finger, matrin-type 4 |
| ZNF750 | zinc finger protein 750 |
| Symbol | Name |
|---|---|
| ABI3BP | ABI family, member 3 (NESH) binding protein |
| ACBD4 | acyl-CoA binding domain containing 4 |
| ACTL8 | actin-like 8 |
| AHDC1 | AT hook, DNA binding motif, containing 1 |
| ALPK1 | alpha-kinase 1 |
| ARHGDIG | Rho GDP dissociation inhibitor (GDI) gamma |
| ARHGEF17 | Rho guanine nucleotide exchange factor (GEF) 17 |
| ARHGEF6 | Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 |
| ARRB1 | arrestin, beta 1 |
| ASB9 | ankyrin repeat and SOCS box containing 9 |
| ATP7B | ATPase, Cu++ transporting, beta polypeptide |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 |
| B3GALT4 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4 |
| B4GALNT1 | beta-1,4-N-acetyl-galactosaminyl transferase 1 |
| B9D2 | B9 protein domain 2 |
| BRINP2 | bone morphogenetic protein/retinoic acid inducible neural-specific 2 |
| BTBD2 | BTB (POZ) domain containing 2 |
| C10ORF95 | chromosome 10 open reading frame 95 |
| CAPRIN2 | caprin family member 2 |
| CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha |
| CEMIP | cell migration inducing protein, hyaluronan binding |
| CLGN | calmegin |
| CRY2 | cryptochrome circadian clock 2 |
| CST6 | cystatin E/M |
| CUEDC1 | CUE domain containing 1 |
| DAPP1 | dual adaptor of phosphotyrosine and 3-phosphoinositides |
| DDX54 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 |
| DSCAM | Down syndrome cell adhesion molecule |
| ELMO3 | engulfment and cell motility 3 |
| ENTPD5 | ectonucleoside triphosphate diphosphohydrolase 5 |
| EXD3 | exonuclease 3'-5' domain containing 3 |
| EXO5 | exonuclease 5 |
| FGF23 | fibroblast growth factor 23 |
| FOSL1 | FOS-like antigen 1 |
| FURIN | furin (paired basic amino acid cleaving enzyme) |
| GLB1L | galactosidase, beta 1-like |
| GLRA1 | glycine receptor, alpha 1 |
| GPNMB | glycoprotein (transmembrane) nmb |
| GSTA4 | glutathione S-transferase alpha 4 |
| GTF2A1 | general transcription factor IIA, 1, 19/37kDa |
| HIST1H2AJ | histone cluster 1, H2aj |
| HIST1H2BO | histone cluster 1, H2bo |
| HMOX1 | heme oxygenase 1 |
| IRF6 | interferon regulatory factor 6 |
| ITGA10 | integrin, alpha 10 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein |
| LHX6 | LIM homeobox 6 |
| LIN7B | lin-7 homolog B (C. elegans) |
| LOC100286895 | cell division cycle 27 homolog pseudogene |
| LRP3 | low density lipoprotein receptor-related protein 3 |
| MAPKBP1 | mitogen-activated protein kinase binding protein 1 |
| MFAP2 | microfibrillar-associated protein 2 |
| MINOS1P1 | mitochondrial inner membrane organizing system 1 pseudogene 1 |
| MPP3 | membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3) |
| MRPL52 | mitochondrial ribosomal protein L52 |
| MUL1 | mitochondrial E3 ubiquitin protein ligase 1 |
| MYO1E | myosin IE |
| NES | nestin |
| NKAIN1 | Na+/K+ transporting ATPase interacting 1 |
| NPFFR1 | neuropeptide FF receptor 1 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa |
| OPA3 | optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) |
| OSMR | oncostatin M receptor |
| PCDHB8 | protocadherin beta 8 |
| PLEKHO1 | pleckstrin homology domain containing, family O member 1 |
| PMCHL1 | pro-melanin-concentrating hormone-like 1, pseudogene |
| PODNL1 | podocan-like 1 |
| PRKCE | protein kinase C, epsilon |
| PSG4 | pregnancy specific beta-1-glycoprotein 4 |
| RCAN3 | RCAN family member 3 |
| RFXAP | regulatory factor X-associated protein |
| RGS2 | regulator of G-protein signaling 2 |
| RNF39 | ring finger protein 39 |
| S100A9 | S100 calcium binding protein A9 |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SDC3 | syndecan 3 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A |
| SENP7 | SUMO1/sentrin specific peptidase 7 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 |
| SIX1 | SIX homeobox 1 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 |
| STEAP1 | six transmembrane epithelial antigen of the prostate 1 |
| STRA6 | stimulated by retinoic acid 6 |
| TARP | TCR gamma alternate reading frame protein |
| TBX19 | T-box 19 |
| TMEM242 | transmembrane protein 242 |
| TMEM45A | transmembrane protein 45A |
| TPST2 | tyrosylprotein sulfotransferase 2 |
| TRAF6 | TNF receptor-associated factor 6, E3 ubiquitin protein ligase |
| TUBG2 | tubulin, gamma 2 |
| USB1 | U6 snRNA biogenesis 1 |
| VASH2 | vasohibin 2 |
| VIPR1 | vasoactive intestinal peptide receptor 1 |
| WDR91 | WD repeat domain 91 |
| ZMAT5 | zinc finger, matrin-type 5 |
| ZNF329 | zinc finger protein 329 |
| ZNF446 | zinc finger protein 446 |
| ZNF747 | zinc finger protein 747 |