iproniazid-6359 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the iproniazid-6359 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABHD17B abhydrolase domain containing 17B
ALDOB aldolase B, fructose-bisphosphate
ALG12 ALG12, alpha-1,6-mannosyltransferase
ANAPC5 anaphase promoting complex subunit 5
ANKLE2 ankyrin repeat and LEM domain containing 2
APOE apolipoprotein E
ATP9A ATPase, class II, type 9A
ATXN3 ataxin 3
BMP7 bone morphogenetic protein 7
C7ORF43 chromosome 7 open reading frame 43
CALM1 calmodulin 1 (phosphorylase kinase, delta)
CD6 CD6 molecule
CDH10 cadherin 10, type 2 (T2-cadherin)
CDRT1 CMT1A duplicated region transcript 1
CEP350 centrosomal protein 350kDa
CYFIP2 cytoplasmic FMR1 interacting protein 2
DENND3 DENN/MADD domain containing 3
DESI2 desumoylating isopeptidase 2
DNAJB5 DnaJ (Hsp40) homolog, subfamily B, member 5
EDA ectodysplasin A
ELL elongation factor RNA polymerase II
ELMO2 engulfment and cell motility 2
EMC3 ER membrane protein complex subunit 3
ENPEP glutamyl aminopeptidase (aminopeptidase A)
FGF20 fibroblast growth factor 20
FOXG1 forkhead box G1
FOXN2 forkhead box N2
FRMPD1 FERM and PDZ domain containing 1
GPC1 glypican 1
HAMP hepcidin antimicrobial peptide
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HOXC10 homeobox C10
IFI44L interferon-induced protein 44-like
IL1RN interleukin 1 receptor antagonist
INO80B INO80 complex subunit B
IPO8 importin 8
ITK IL2-inducible T-cell kinase
KDM4C lysine (K)-specific demethylase 4C
KHDRBS2 KH domain containing, RNA binding, signal transduction associated 2
KLF13 Kruppel-like factor 13
LAMA4 laminin, alpha 4
LAMP1 lysosomal-associated membrane protein 1
LAX1 lymphocyte transmembrane adaptor 1
METTL16 methyltransferase like 16
MGAT2 mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
MVK mevalonate kinase
MXD4 MAX dimerization protein 4
MYL10 myosin, light chain 10, regulatory
MYO1F myosin IF
NCOR2 nuclear receptor corepressor 2
NDE1 nudE neurodevelopment protein 1
NFIB nuclear factor I/B
NPFFR1 neuropeptide FF receptor 1
NRIP3 nuclear receptor interacting protein 3
OGT O-linked N-acetylglucosamine (GlcNAc) transferase
OSMR oncostatin M receptor
PADI2 peptidyl arginine deiminase, type II
PDE4DIP phosphodiesterase 4D interacting protein
PI4K2A phosphatidylinositol 4-kinase type 2 alpha
PKNOX1 PBX/knotted 1 homeobox 1
PLK3 polo-like kinase 3
PRB3 proline-rich protein BstNI subfamily 3
PRDM14 PR domain containing 14
PTPN11 protein tyrosine phosphatase, non-receptor type 11
RASSF4 Ras association (RalGDS/AF-6) domain family member 4
RBBP9 retinoblastoma binding protein 9
RGS12 regulator of G-protein signaling 12
RGS14 regulator of G-protein signaling 14
RIMS3 regulating synaptic membrane exocytosis 3
RNF5 ring finger protein 5, E3 ubiquitin protein ligase
RPL7 ribosomal protein L7
RWDD2A RWD domain containing 2A
S100A13 S100 calcium binding protein A13
SAYSD1 SAYSVFN motif domain containing 1
SCARA3 scavenger receptor class A, member 3
SCN10A sodium channel, voltage gated, type X alpha subunit
SENP5 SUMO1/sentrin specific peptidase 5
SFI1 Sfi1 homolog, spindle assembly associated (yeast)
SLC1A7 solute carrier family 1 (glutamate transporter), member 7
SLC25A30 solute carrier family 25, member 30
SOX15 SRY (sex determining region Y)-box 15
SRD5A3 steroid 5 alpha-reductase 3
SUPT6H suppressor of Ty 6 homolog (S. cerevisiae)
TBC1D17 TBC1 domain family, member 17
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TGFBI transforming growth factor, beta-induced, 68kDa
TMF1 TATA element modulatory factor 1
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TRAK1 trafficking protein, kinesin binding 1
VCAM1 vascular cell adhesion molecule 1
VCAN versican
VGF VGF nerve growth factor inducible
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4
ZNF117 zinc finger protein 117
ZNF862 zinc finger protein 862

decreased expression

Symbol Name
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
ADAMTS3 ADAM metallopeptidase with thrombospondin type 1 motif, 3
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
ALKBH4 alkB, alkylation repair homolog 4 (E. coli)
AP1B1 adaptor-related protein complex 1, beta 1 subunit
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
BNC1 basonuclin 1
C11ORF30 chromosome 11 open reading frame 30
C11ORF63 chromosome 11 open reading frame 63
C17ORF70 chromosome 17 open reading frame 70
CADPS2 Ca++-dependent secretion activator 2
CCDC69 coiled-coil domain containing 69
CCNA1 cyclin A1
CDH3 cadherin 3, type 1, P-cadherin (placental)
CDK3 cyclin-dependent kinase 3
CHST8 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
CNIH3 cornichon family AMPA receptor auxiliary protein 3
CRYBA2 crystallin, beta A2
CTC1 CTS telomere maintenance complex component 1
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6
DHX38 DEAH (Asp-Glu-Ala-His) box polypeptide 38
ETV4 ets variant 4
EYA4 EYA transcriptional coactivator and phosphatase 4
FA2H fatty acid 2-hydroxylase
FAM204A family with sequence similarity 204, member A
FBXL6 F-box and leucine-rich repeat protein 6
FBXL7 F-box and leucine-rich repeat protein 7
FBXO2 F-box protein 2
FCGRT Fc fragment of IgG, receptor, transporter, alpha
FCHO1 FCH domain only 1
FUZ fuzzy planar cell polarity protein
GINS4 GINS complex subunit 4 (Sld5 homolog)
GIT2 G protein-coupled receptor kinase interacting ArfGAP 2
GJC1 gap junction protein, gamma 1, 45kDa
HDAC5 histone deacetylase 5
HDAC7 histone deacetylase 7
HIRA histone cell cycle regulator
HMBOX1 homeobox containing 1
HOXA6 homeobox A6
HPS6 Hermansky-Pudlak syndrome 6
HSPA2 heat shock 70kDa protein 2
IFNAR1 interferon (alpha, beta and omega) receptor 1
IL15RA interleukin 15 receptor, alpha
INO80D INO80 complex subunit D
KRI1 KRI1 homolog (S. cerevisiae)
LPPR4 lipid phosphate phosphatase-related protein type 4
LRP3 low density lipoprotein receptor-related protein 3
LRRC37A3 leucine rich repeat containing 37, member A3
MAGEH1 melanoma antigen family H1
MAN2C1 mannosidase, alpha, class 2C, member 1
MBTD1 mbt domain containing 1
MGAT4A mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
MX1 MX dynamin-like GTPase 1
MYO1E myosin IE
MYOZ3 myozenin 3
NDRG4 NDRG family member 4
NOTCH1 notch 1
NR1H3 nuclear receptor subfamily 1, group H, member 3
NUBPL nucleotide binding protein-like
P2RY2 purinergic receptor P2Y, G-protein coupled, 2
PDIA3 protein disulfide isomerase family A, member 3
PILRB paired immunoglobin-like type 2 receptor beta
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
POLR3D polymerase (RNA) III (DNA directed) polypeptide D, 44kDa
PPP1R13L protein phosphatase 1, regulatory subunit 13 like
PRICKLE3 prickle homolog 3 (Drosophila)
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RAB5B RAB5B, member RAS oncogene family
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
SDC3 syndecan 3
SHPK sedoheptulokinase
SLC12A6 solute carrier family 12 (potassium/chloride transporter), member 6
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SLC4A2 solute carrier family 4 (anion exchanger), member 2
SLMO1 slowmo homolog 1 (Drosophila)
STX1A syntaxin 1A (brain)
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TEX40 testis expressed 40
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TMEM8A transmembrane protein 8A
TRIM45 tripartite motif containing 45
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein
TSC22D4 TSC22 domain family, member 4
TTC4 tetratricopeptide repeat domain 4
TUBA3C tubulin, alpha 3c
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
UEVLD UEV and lactate/malate dehyrogenase domains
UNC93B1 unc-93 homolog B1 (C. elegans)
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
VEZT vezatin, adherens junctions transmembrane protein
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
ZNF10 zinc finger protein 10
ZNF358 zinc finger protein 358
ZNF606 zinc finger protein 606
ZNF652 zinc finger protein 652
ZNF665 zinc finger protein 665
ZNF747 zinc finger protein 747