irak1 Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description interleukin-1 receptor-associated kinase 1|This gene encodes the interleukin-1 receptor-associated kinase 1, one of two putative serine/threonine kinases that become associated with the interleukin-1 receptor (IL1R) upon stimulation. This gene is partially responsible for IL1-induced upregulation of the transcription factor NF-kappa B. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 3654)
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Genes

45 genes co-occuring with the biological term irak1 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ADAMTS4 ADAM metallopeptidase with thrombospondin type 1 motif, 4
ALOX5AP arachidonate 5-lipoxygenase-activating protein
BCL10 B-cell CLL/lymphoma 10
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase
BUB1 BUB1 mitotic checkpoint serine/threonine kinase
CFH complement factor H
CHEK1 checkpoint kinase 1
CRP C-reactive protein, pentraxin-related
FABP2 fatty acid binding protein 2, intestinal
FBXW11 F-box and WD repeat domain containing 11
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
IL10 interleukin 10
IL12B interleukin 12B
IL15 interleukin 15
IL17A interleukin 17A
IL1B interleukin 1, beta
IRAK1 interleukin-1 receptor-associated kinase 1
IRAK2 interleukin-1 receptor-associated kinase 2
IRAK4 interleukin-1 receptor-associated kinase 4
MAL mal, T-cell differentiation protein
MAP3K7 mitogen-activated protein kinase kinase kinase 7
MECP2 methyl CpG binding protein 2
MIR146A microRNA 146a
MIR21 microRNA 21
MMP13 matrix metallopeptidase 13
MYD88 myeloid differentiation primary response 88
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NFKBIZ nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta
NLRP12 NLR family, pyrin domain containing 12
NUMB numb homolog (Drosophila)
PELI2 pellino E3 ubiquitin protein ligase family member 2
PRKCD protein kinase C, delta
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
PTPN6 protein tyrosine phosphatase, non-receptor type 6
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
SELP selectin P (granule membrane protein 140kDa, antigen CD62)
SMPD3 sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II)
TLR2 toll-like receptor 2
TLR3 toll-like receptor 3
TLR4 toll-like receptor 4
TNF tumor necrosis factor
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TOLLIP toll interacting protein
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
VASP vasodilator-stimulated phosphoprotein