irak3 Gene Set

Dataset	GeneRIF Biological Term Annotations
Category	structural or functional annotations
Type	biological term
Description	interleukin-1 receptor-associated kinase 3\|This gene encodes a member of the interleukin-1 receptor-associated kinase protein family. Members of this family are essential components of the Toll/IL-R immune signal transduction pathways. This protein is primarily expressed in monocytes and macrophages and functions as a negative regulator of Toll-like receptor signaling. Mutations in this gene are associated with a susceptibility to asthma. Alternate splicing results in multiple transcript variants. [provided by RefSeq, May 2010] (NCBI Entrez Gene Database, 11213)
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Genes

10 genes co-occuring with the biological term irak3 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol	Name
ALOX5	arachidonate 5-lipoxygenase
IRAK1	interleukin-1 receptor-associated kinase 1
IRAK3	interleukin-1 receptor-associated kinase 3
ITGB2	integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
NCF2	neutrophil cytosolic factor 2
NFKB1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
ORMDL3	ORMDL sphingolipid biosynthesis regulator 3
SELP	selectin P (granule membrane protein 140kDa, antigen CD62)
SOD1	superoxide dismutase 1, soluble
STAT1	signal transducer and activator of transcription 1, 91kDa