irf1 Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description interferon regulatory factor 1|IRF1 encodes interferon regulatory factor 1, a member of the interferon regulatory transcription factor (IRF) family. IRF1 serves as an activator of interferons alpha and beta transcription, and in mouse it has been shown to be required for double-stranded RNA induction of these genes. IRF1 also functions as a transcription activator of genes induced by interferons alpha, beta, and gamma. Further, IRF1 has been shown to play roles in regulating apoptosis and tumor-suppressoion. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 3659)
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Genes

85 genes co-occuring with the biological term irf1 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ANXA2 annexin A2
ATM ATM serine/threonine kinase
B2M beta-2-microglobulin
BBC3 BCL2 binding component 3
CASP8 caspase 8, apoptosis-related cysteine peptidase
CCL5 chemokine (C-C motif) ligand 5
CD200 CD200 molecule
CD40 CD40 molecule, TNF receptor superfamily member 5
CD80 CD80 molecule
CD83 CD83 molecule
CDK2 cyclin-dependent kinase 2
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CXCL10 chemokine (C-X-C motif) ligand 10
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DUSP16 dual specificity phosphatase 16
EGFR epidermal growth factor receptor
ESRRA estrogen-related receptor alpha
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
FOXA1 forkhead box A1
FOXP3 forkhead box P3
GAGE7 G antigen 7
HLA-A major histocompatibility complex, class I, A
HTATSF1 HIV-1 Tat specific factor 1
ICAM1 intercellular adhesion molecule 1
IFI35 interferon-induced protein 35
IFIT3 interferon-induced protein with tetratricopeptide repeats 3
IFNG interferon, gamma
IFNGR1 interferon gamma receptor 1
IFNGR2 interferon gamma receptor 2 (interferon gamma transducer 1)
IGF1 insulin-like growth factor 1 (somatomedin C)
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
IL11 interleukin 11
IL1B interleukin 1, beta
IL2RA interleukin 2 receptor, alpha
IL4 interleukin 4
IL6 interleukin 6
IRF1 interferon regulatory factor 1
IRF2 interferon regulatory factor 2
IRF7 interferon regulatory factor 7
IRF8 interferon regulatory factor 8
LEPR leptin receptor
LIF leukemia inhibitory factor
MAPK8 mitogen-activated protein kinase 8
MIR126 microRNA 126
MIR383 microRNA 383
NCOA2 nuclear receptor coactivator 2
NEWENTRY Record to support submission of GeneRIFs for a gene not in Gene (human; man).
NF1 neurofibromin 1
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin)
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
PIAS1 protein inhibitor of activated STAT, 1
POLH polymerase (DNA directed), eta
PPARG peroxisome proliferator-activated receptor gamma
PSMB10 proteasome (prosome, macropain) subunit, beta type, 10
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9
RARA retinoic acid receptor, alpha
RARB retinoic acid receptor, beta
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
SELE selectin E
SLC26A6 solute carrier family 26 (anion exchanger), member 6
SMAD7 SMAD family member 7
SOCS1 suppressor of cytokine signaling 1
SP1 Sp1 transcription factor
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT2 signal transducer and activator of transcription 2, 113kDa
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
TAPBP TAP binding protein (tapasin)
TEK TEK tyrosine kinase, endothelial
TERT telomerase reverse transcriptase
TGFB1 transforming growth factor, beta 1
TLR4 toll-like receptor 4
TNF tumor necrosis factor
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TP53 tumor protein p53
TRIM28 tripartite motif containing 28
USP22 ubiquitin specific peptidase 22
VCAM1 vascular cell adhesion molecule 1
XAF1 XIAP associated factor 1
XBP1 X-box binding protein 1
YBX1 Y box binding protein 1