irf7 Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description interferon regulatory factor 7|IRF7 encodes interferon regulatory factor 7, a member of the interferon regulatory transcription factor (IRF) family. IRF7 has been shown to play a role in the transcriptional activation of virus-inducible cellular genes, including interferon beta chain genes. Inducible expression of IRF7 is largely restricted to lymphoid tissue. Multiple IRF7 transcript variants have been identified, although the functional consequences of these have not yet been established. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 3665)
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Genes

31 genes co-occuring with the biological term irf7 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
BRCA1 breast cancer 1, early onset
BST2 bone marrow stromal cell antigen 2
CD80 CD80 molecule
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
FOXP3 forkhead box P3
IFN1@ interferon, type 1, cluster
IFNB1 interferon, beta 1, fibroblast
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
IL12B interleukin 12B
IRF1 interferon regulatory factor 1
IRF3 interferon regulatory factor 3
IRF5 interferon regulatory factor 5
IRF7 interferon regulatory factor 7
IRF9 interferon regulatory factor 9
KAT2B K(lysine) acetyltransferase 2B
MAPK1 mitogen-activated protein kinase 1
MYD88 myeloid differentiation primary response 88
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
STAT1 signal transducer and activator of transcription 1, 91kDa
SUMO2 small ubiquitin-like modifier 2
TBK1 TANK-binding kinase 1
TICAM2 toll-like receptor adaptor molecule 2
TLR7 toll-like receptor 7
TLR9 toll-like receptor 9
TNF tumor necrosis factor
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TRIM21 tripartite motif containing 21
TRIM7 tripartite motif containing 7