| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
| Downloads & Tools |
198 genes differentially expressed following the irinotecan-7530 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCF2 | ATP-binding cassette, sub-family F (GCN20), member 2 |
| ACTA2 | actin, alpha 2, smooth muscle, aorta |
| ADM | adrenomedullin |
| ADPRM | ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent |
| ANKRA2 | ankyrin repeat, family A (RFXANK-like), 2 |
| AOC3 | amine oxidase, copper containing 3 |
| ATF3 | activating transcription factor 3 |
| ATG12 | autophagy related 12 |
| BLNK | B-cell linker |
| BTG2 | BTG family, member 2 |
| C11ORF68 | chromosome 11 open reading frame 68 |
| C17ORF80 | chromosome 17 open reading frame 80 |
| CD83 | CD83 molecule |
| CDKL3 | cyclin-dependent kinase-like 3 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
| CEL | carboxyl ester lipase |
| CFHR4 | complement factor H-related 4 |
| CSF1R | colony stimulating factor 1 receptor |
| CYR61 | cysteine-rich, angiogenic inducer, 61 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DIEXF | digestive organ expansion factor homolog (zebrafish) |
| DIS3 | DIS3 exosome endoribonuclease and 3'-5' exoribonuclease |
| ECM1 | extracellular matrix protein 1 |
| ERCC4 | excision repair cross-complementation group 4 |
| ETS2 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 |
| FBXL8 | F-box and leucine-rich repeat protein 8 |
| FOSL1 | FOS-like antigen 1 |
| FSCN1 | fascin actin-bundling protein 1 |
| GABBR2 | gamma-aminobutyric acid (GABA) B receptor, 2 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha |
| GAMT | guanidinoacetate N-methyltransferase |
| GM2A | GM2 ganglioside activator |
| GPR137 | G protein-coupled receptor 137 |
| GPR87 | G protein-coupled receptor 87 |
| GRIN2C | glutamate receptor, ionotropic, N-methyl D-aspartate 2C |
| HBEGF | heparin-binding EGF-like growth factor |
| HIC2 | hypermethylated in cancer 2 |
| HIST1H3B | histone cluster 1, H3b |
| HPX | hemopexin |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein |
| IFT27 | intraflagellar transport 27 |
| JAG1 | jagged 1 |
| JUN | jun proto-oncogene |
| KCNG1 | potassium channel, voltage gated modifier subfamily G, member 1 |
| KCNS1 | potassium voltage-gated channel, modifier subfamily S, member 1 |
| LEFTY1 | left-right determination factor 1 |
| LIF | leukemia inhibitory factor |
| LOC157562 | uncharacterized LOC157562 |
| LSS | lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) |
| MAFB | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase |
| MR1 | major histocompatibility complex, class I-related |
| MTL5 | metallothionein-like 5, testis-specific (tesmin) |
| MXD4 | MAX dimerization protein 4 |
| NFYA | nuclear transcription factor Y, alpha |
| NGDN | neuroguidin, EIF4E binding protein |
| NHLH2 | nescient helix loop helix 2 |
| NUP88 | nucleoporin 88kDa |
| NUPR1 | nuclear protein, transcriptional regulator, 1 |
| NYNRIN | NYN domain and retroviral integrase containing |
| OVGP1 | oviductal glycoprotein 1, 120kDa |
| P2RY11 | purinergic receptor P2Y, G-protein coupled, 11 |
| PABPN1 | poly(A) binding protein, nuclear 1 |
| PARD6B | par-6 family cell polarity regulator beta |
| PDE4A | phosphodiesterase 4A, cAMP-specific |
| PFKFB2 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 |
| PGF | placental growth factor |
| PIDD1 | p53-induced death domain protein 1 |
| PLAU | plasminogen activator, urokinase |
| PLEKHF1 | pleckstrin homology domain containing, family F (with FYVE domain) member 1 |
| PLEKHO2 | pleckstrin homology domain containing, family O member 2 |
| PLK3 | polo-like kinase 3 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 |
| PSMD11 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 |
| PYGM | phosphorylase, glycogen, muscle |
| RETSAT | retinol saturase (all-trans-retinol 13,14-reductase) |
| RFPL3S | RFPL3 antisense |
| RNF6 | ring finger protein (C3H2C3 type) 6 |
| RSL1D1 | ribosomal L1 domain containing 1 |
| RTCA | RNA 3'-terminal phosphate cyclase |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 |
| SCAND2P | SCAN domain containing 2 pseudogene |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 |
| SESN1 | sestrin 1 |
| SFN | stratifin |
| SIRT4 | sirtuin 4 |
| SLC30A1 | solute carrier family 30 (zinc transporter), member 1 |
| SLC52A1 | solute carrier family 52 (riboflavin transporter), member 1 |
| SOCS1 | suppressor of cytokine signaling 1 |
| TBL2 | transducin (beta)-like 2 |
| TMEM183A | transmembrane protein 183A |
| UCN | urocortin |
| VPREB3 | pre-B lymphocyte 3 |
| ZDHHC11 | zinc finger, DHHC-type containing 11 |
| ZNF250 | zinc finger protein 250 |
| ZNF750 | zinc finger protein 750 |
| ZNF778 | zinc finger protein 778 |
| ZNF862 | zinc finger protein 862 |
| Symbol | Name |
|---|---|
| ACAP2 | ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 |
| ACVR1 | activin A receptor, type I |
| ADGRL2 | adhesion G protein-coupled receptor L2 |
| AGO2 | argonaute RISC catalytic component 2 |
| ANKRD11 | ankyrin repeat domain 11 |
| ANKRD28 | ankyrin repeat domain 28 |
| ANKS1A | ankyrin repeat and sterile alpha motif domain containing 1A |
| ARHGAP11A | Rho GTPase activating protein 11A |
| ARHGAP12 | Rho GTPase activating protein 12 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) |
| BMPR1A | bone morphogenetic protein receptor, type IA |
| BRINP3 | bone morphogenetic protein/retinoic acid inducible neural-specific 3 |
| BUB1B | BUB1 mitotic checkpoint serine/threonine kinase B |
| C4ORF19 | chromosome 4 open reading frame 19 |
| CDK5RAP2 | CDK5 regulatory subunit associated protein 2 |
| CENPE | centromere protein E, 312kDa |
| CLASP1 | cytoplasmic linker associated protein 1 |
| DAAM1 | dishevelled associated activator of morphogenesis 1 |
| DDX10 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 |
| DENND1B | DENN/MADD domain containing 1B |
| DTL | denticleless E3 ubiquitin protein ligase homolog (Drosophila) |
| EFNA4 | ephrin-A4 |
| EHBP1 | EH domain binding protein 1 |
| ERBB2IP | erbb2 interacting protein |
| EYA2 | EYA transcriptional coactivator and phosphatase 2 |
| FAM69A | family with sequence similarity 69, member A |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) |
| GHR | growth hormone receptor |
| GLCE | glucuronic acid epimerase |
| GRHL2 | grainyhead-like 2 (Drosophila) |
| GSK3B | glycogen synthase kinase 3 beta |
| GTF2IRD1 | GTF2I repeat domain containing 1 |
| HIVEP1 | human immunodeficiency virus type I enhancer binding protein 1 |
| HJURP | Holliday junction recognition protein |
| HMBOX1 | homeobox containing 1 |
| INSIG2 | insulin induced gene 2 |
| JARID2 | jumonji, AT rich interactive domain 2 |
| JMJD1C | jumonji domain containing 1C |
| KIF11 | kinesin family member 11 |
| KIF14 | kinesin family member 14 |
| KIF16B | kinesin family member 16B |
| KIF18A | kinesin family member 18A |
| KIF1B | kinesin family member 1B |
| KIF20B | kinesin family member 20B |
| KIZ | kizuna centrosomal protein |
| KRBOX4 | KRAB box domain containing 4 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 |
| MAP4K3 | mitogen-activated protein kinase kinase kinase kinase 3 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 |
| MCM9 | minichromosome maintenance complex component 9 |
| MEIS1 | Meis homeobox 1 |
| MKL2 | MKL/myocardin-like 2 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 |
| NCAPH | non-SMC condensin I complex, subunit H |
| NDC80 | NDC80 kinetochore complex component |
| NIPBL | Nipped-B homolog (Drosophila) |
| NLK | nemo-like kinase |
| NRIP1 | nuclear receptor interacting protein 1 |
| PDZRN3 | PDZ domain containing ring finger 3 |
| PHF21A | PHD finger protein 21A |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 |
| PLEKHA6 | pleckstrin homology domain containing, family A member 6 |
| POLR3B | polymerase (RNA) III (DNA directed) polypeptide B |
| PPM1H | protein phosphatase, Mg2+/Mn2+ dependent, 1H |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A |
| PRR15L | proline rich 15-like |
| PTPRK | protein tyrosine phosphatase, receptor type, K |
| RAPGEF6 | Rap guanine nucleotide exchange factor (GEF) 6 |
| RASA1 | RAS p21 protein activator (GTPase activating protein) 1 |
| RBM47 | RNA binding motif protein 47 |
| RCOR1 | REST corepressor 1 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit |
| RNF121 | ring finger protein 121 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 |
| SFMBT1 | Scm-like with four mbt domains 1 |
| SHROOM2 | shroom family member 2 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 |
| STARD13 | StAR-related lipid transfer (START) domain containing 13 |
| SYT1 | synaptotagmin I |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 |
| TASP1 | taspase, threonine aspartase, 1 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 |
| TNS3 | tensin 3 |
| TPTE | transmembrane phosphatase with tensin homology |
| TRAF5 | TNF receptor-associated factor 5 |
| TRMT11 | tRNA methyltransferase 11 homolog (S. cerevisiae) |
| TRPS1 | trichorhinophalangeal syndrome I |
| TTK | TTK protein kinase |
| TULP4 | tubby like protein 4 |
| TYW1 | tRNA-yW synthesizing protein 1 homolog (S. cerevisiae) |
| USP6NL | USP6 N-terminal like |
| UVRAG | UV radiation resistance associated |
| WDR26 | WD repeat domain 26 |
| WDR44 | WD repeat domain 44 |
| WDR7 | WD repeat domain 7 |
| WDR70 | WD repeat domain 70 |
| WWP1 | WW domain containing E3 ubiquitin protein ligase 1 |
| ZHX2 | zinc fingers and homeoboxes 2 |
| ZNF165 | zinc finger protein 165 |
