| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the irinotecan-7535 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCF2 | ATP-binding cassette, sub-family F (GCN20), member 2 |
| ADM | adrenomedullin |
| ADPRM | ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent |
| AQP3 | aquaporin 3 (Gill blood group) |
| ATF3 | activating transcription factor 3 |
| BAMBI | BMP and activin membrane-bound inhibitor |
| BRD2 | bromodomain containing 2 |
| BTBD18 | BTB (POZ) domain containing 18 |
| C19ORF66 | chromosome 19 open reading frame 66 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
| CDKN1C | cyclin-dependent kinase inhibitor 1C (p57, Kip2) |
| CEL | carboxyl ester lipase |
| CHCHD7 | coiled-coil-helix-coiled-coil-helix domain containing 7 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 |
| COL6A1 | collagen, type VI, alpha 1 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 |
| CXCL6 | chemokine (C-X-C motif) ligand 6 |
| CXCR4 | chemokine (C-X-C motif) receptor 4 |
| DIEXF | digestive organ expansion factor homolog (zebrafish) |
| DIO3 | deiodinase, iodothyronine, type III |
| DLX2 | distal-less homeobox 2 |
| DNAL4 | dynein, axonemal, light chain 4 |
| DUSP1 | dual specificity phosphatase 1 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 |
| ECE1 | endothelin converting enzyme 1 |
| EFNA3 | ephrin-A3 |
| EIF5 | eukaryotic translation initiation factor 5 |
| ELOVL4 | ELOVL fatty acid elongase 4 |
| EMC3 | ER membrane protein complex subunit 3 |
| EN2 | engrailed homeobox 2 |
| FCER1G | Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide |
| FLRT3 | fibronectin leucine rich transmembrane protein 3 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog |
| FOXC1 | forkhead box C1 |
| GADD45B | growth arrest and DNA-damage-inducible, beta |
| GPER1 | G protein-coupled estrogen receptor 1 |
| H2AFJ | H2A histone family, member J |
| H2AFX | H2A histone family, member X |
| H3F3B | H3 histone, family 3B (H3.3B) |
| HBEGF | heparin-binding EGF-like growth factor |
| HEXIM1 | hexamethylene bis-acetamide inducible 1 |
| HIST3H2A | histone cluster 3, H2a |
| HOXB5 | homeobox B5 |
| HSPA2 | heat shock 70kDa protein 2 |
| IFI30 | interferon, gamma-inducible protein 30 |
| IFI6 | interferon, alpha-inducible protein 6 |
| IFT22 | intraflagellar transport 22 |
| IL11 | interleukin 11 |
| IL6 | interleukin 6 |
| ING1 | inhibitor of growth family, member 1 |
| INSIG1 | insulin induced gene 1 |
| JUNB | jun B proto-oncogene |
| JUND | jun D proto-oncogene |
| KCNJ2 | potassium channel, inwardly rectifying subfamily J, member 2 |
| LEFTY1 | left-right determination factor 1 |
| LOC157562 | uncharacterized LOC157562 |
| LSM4 | LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae) |
| LTB4R | leukotriene B4 receptor |
| MED18 | mediator complex subunit 18 |
| MNX1 | motor neuron and pancreas homeobox 1 |
| NGDN | neuroguidin, EIF4E binding protein |
| NUPR1 | nuclear protein, transcriptional regulator, 1 |
| NXF1 | nuclear RNA export factor 1 |
| OSR2 | odd-skipped related transciption factor 2 |
| PABPN1 | poly(A) binding protein, nuclear 1 |
| PAQR6 | progestin and adipoQ receptor family member VI |
| PDE4DIP | phosphodiesterase 4D interacting protein |
| PFKFB2 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 |
| PIDD1 | p53-induced death domain protein 1 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 |
| PRDM2 | PR domain containing 2, with ZNF domain |
| PRDX2 | peroxiredoxin 2 |
| RASSF1 | Ras association (RalGDS/AF-6) domain family member 1 |
| RFPL3S | RFPL3 antisense |
| RHOB | ras homolog family member B |
| RND1 | Rho family GTPase 1 |
| RPL31 | ribosomal protein L31 |
| RPS28 | ribosomal protein S28 |
| RSL1D1 | ribosomal L1 domain containing 1 |
| RSRP1 | arginine/serine-rich protein 1 |
| SAP18 | Sin3A-associated protein, 18kDa |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 |
| SCG5 | secretogranin V |
| SGK1 | serum/glucocorticoid regulated kinase 1 |
| SIRT4 | sirtuin 4 |
| SLC30A1 | solute carrier family 30 (zinc transporter), member 1 |
| SMARCD3 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 |
| SOWAHC | sosondowah ankyrin repeat domain family member C |
| SQSTM1 | sequestosome 1 |
| SYNGR3 | synaptogyrin 3 |
| TBL2 | transducin (beta)-like 2 |
| TNFSF9 | tumor necrosis factor (ligand) superfamily, member 9 |
| TOB2 | transducer of ERBB2, 2 |
| TSPYL2 | TSPY-like 2 |
| TUBB2A | tubulin, beta 2A class IIa |
| UCN | urocortin |
| ULBP2 | UL16 binding protein 2 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 |
| ZNF137P | zinc finger protein 137, pseudogene |
| ZNF468 | zinc finger protein 468 |
| Symbol | Name |
|---|---|
| ABI3BP | ABI family, member 3 (NESH) binding protein |
| ANKRD11 | ankyrin repeat domain 11 |
| ANKRD17 | ankyrin repeat domain 17 |
| ANKS1A | ankyrin repeat and sterile alpha motif domain containing 1A |
| ARMCX5 | armadillo repeat containing, X-linked 5 |
| ARSJ | arylsulfatase family, member J |
| ATXN2 | ataxin 2 |
| BARD1 | BRCA1 associated RING domain 1 |
| BCAR3 | breast cancer anti-estrogen resistance 3 |
| BNC2 | basonuclin 2 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa |
| BUB1B | BUB1 mitotic checkpoint serine/threonine kinase B |
| CAB39 | calcium binding protein 39 |
| CEP192 | centrosomal protein 192kDa |
| CHRM3 | cholinergic receptor, muscarinic 3 |
| CHST15 | carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 |
| COL4A3BP | collagen, type IV, alpha 3 (Goodpasture antigen) binding protein |
| CRYBG3 | beta-gamma crystallin domain containing 3 |
| DOCK4 | dedicator of cytokinesis 4 |
| DTL | denticleless E3 ubiquitin protein ligase homolog (Drosophila) |
| EFTUD1 | elongation factor Tu GTP binding domain containing 1 |
| ERBB2IP | erbb2 interacting protein |
| FAM188A | family with sequence similarity 188, member A |
| FCHSD2 | FCH and double SH3 domains 2 |
| FNBP1L | formin binding protein 1-like |
| FNDC3B | fibronectin type III domain containing 3B |
| GLI3 | GLI family zinc finger 3 |
| GPATCH2 | G patch domain containing 2 |
| GPHN | gephyrin |
| GRAMD1B | GRAM domain containing 1B |
| GRHL2 | grainyhead-like 2 (Drosophila) |
| GSK3B | glycogen synthase kinase 3 beta |
| HIST1H1D | histone cluster 1, H1d |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 |
| HMGA2 | high mobility group AT-hook 2 |
| HOMER1 | homer scaffolding protein 1 |
| HS3ST3A1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 |
| JMJD1C | jumonji domain containing 1C |
| KAT6B | K(lysine) acetyltransferase 6B |
| KIAA0020 | KIAA0020 |
| KIF15 | kinesin family member 15 |
| KIF18A | kinesin family member 18A |
| KIF20B | kinesin family member 20B |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 |
| LMNB1 | lamin B1 |
| MAD1L1 | MAD1 mitotic arrest deficient-like 1 (yeast) |
| MAP4K3 | mitogen-activated protein kinase kinase kinase kinase 3 |
| MEIS2 | Meis homeobox 2 |
| MGA | MGA, MAX dimerization protein |
| MKL2 | MKL/myocardin-like 2 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 |
| MTCL1 | microtubule crosslinking factor 1 |
| NAV2 | neuron navigator 2 |
| NBEA | neurobeachin |
| NIPBL | Nipped-B homolog (Drosophila) |
| NRIP1 | nuclear receptor interacting protein 1 |
| OSBPL9 | oxysterol binding protein-like 9 |
| PHF21A | PHD finger protein 21A |
| PHLPP1 | PH domain and leucine rich repeat protein phosphatase 1 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 |
| POLR3B | polymerase (RNA) III (DNA directed) polypeptide B |
| POU2F1 | POU class 2 homeobox 1 |
| PPAP2B | phosphatidic acid phosphatase type 2B |
| PPARG | peroxisome proliferator-activated receptor gamma |
| PPM1H | protein phosphatase, Mg2+/Mn2+ dependent, 1H |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A |
| PRRG1 | proline rich Gla (G-carboxyglutamic acid) 1 |
| PTPN4 | protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte) |
| PUM1 | pumilio RNA-binding family member 1 |
| RAPGEF6 | Rap guanine nucleotide exchange factor (GEF) 6 |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 |
| RCOR1 | REST corepressor 1 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit |
| SCAF8 | SR-related CTD-associated factor 8 |
| SEC24B | SEC24 family member B |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A |
| SGMS1 | sphingomyelin synthase 1 |
| SLC25A13 | solute carrier family 25 (aspartate/glutamate carrier), member 13 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 |
| STAM | signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 |
| STX18 | syntaxin 18 |
| STX5 | syntaxin 5 |
| TACC2 | transforming, acidic coiled-coil containing protein 2 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) |
| TENM4 | teneurin transmembrane protein 4 |
| TNS3 | tensin 3 |
| TPST1 | tyrosylprotein sulfotransferase 1 |
| TRPS1 | trichorhinophalangeal syndrome I |
| TYW1 | tRNA-yW synthesizing protein 1 homolog (S. cerevisiae) |
| UVRAG | UV radiation resistance associated |
| VEGFC | vascular endothelial growth factor C |
| WDR70 | WD repeat domain 70 |
| YEATS2 | YEATS domain containing 2 |
| ZC3H3 | zinc finger CCCH-type containing 3 |
| ZFHX4 | zinc finger homeobox 4 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 |
| ZNF248 | zinc finger protein 248 |
| ZNF33B | zinc finger protein 33B |
