irinotecan Gene Set

Dataset CTD Gene-Chemical Interactions
Category physical interactions
Type chemical
External Link http://ctdbase.org/detail.go?type=chem&acc=C051890
Similar Terms
Downloads & Tools

Genes

116 genes/proteins interacting with the chemical irinotecan from the curated CTD Gene-Chemical Interactions dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
ACAT1 acetyl-CoA acetyltransferase 1
ACHE acetylcholinesterase (Yt blood group)
AK2 adenylate kinase 2
ARF1 ADP-ribosylation factor 1
ATM ATM serine/threonine kinase
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4
ATP6V0B ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b
ATP7A ATPase, Cu++ transporting, alpha polypeptide
BAX BCL2-associated X protein
BCL2 B-cell CLL/lymphoma 2
BID BH3 interacting domain death agonist
BIRC5 baculoviral IAP repeat containing 5
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP8 caspase 8, apoptosis-related cysteine peptidase
CASP9 caspase 9, apoptosis-related cysteine peptidase
CCNB1IP1 cyclin B1 interacting protein 1, E3 ubiquitin protein ligase
CCNB2 cyclin B2
CDC20 cell division cycle 20
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN2A cyclin-dependent kinase inhibitor 2A
CEL carboxyl ester lipase
CES1 carboxylesterase 1
CES2 carboxylesterase 2
CES3 carboxylesterase 3
CFLAR CASP8 and FADD-like apoptosis regulator
CHEK1 checkpoint kinase 1
CHEK2 checkpoint kinase 2
CLTC clathrin, heavy chain (Hc)
COL7A1 collagen, type VII, alpha 1
CTBP2 C-terminal binding protein 2
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4
CYR61 cysteine-rich, angiogenic inducer, 61
DBF4 DBF4 zinc finger
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
DLG1 discs, large homolog 1 (Drosophila)
DPYD dihydropyrimidine dehydrogenase
EGFR epidermal growth factor receptor
ERCC1 excision repair cross-complementation group 1
FAS Fas cell surface death receptor
HES1 hes family bHLH transcription factor 1
IFNG interferon, gamma
IL1B interleukin 1, beta
IL2 interleukin 2
IL6 interleukin 6
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide)
KANSL1 KAT8 regulatory NSL complex subunit 1
KRT18 keratin 18, type I
LSM7 LSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae)
MALAT1 metastasis associated lung adenocarcinoma transcript 1 (non-protein coding)
MAPK1 mitogen-activated protein kinase 1
MAPK3 mitogen-activated protein kinase 3
MCCC2 methylcrotonoyl-CoA carboxylase 2 (beta)
MCL1 myeloid cell leukemia 1
MLH1 mutL homolog 1
MSH2 mutS homolog 2
MYB v-myb avian myeloblastosis viral oncogene homolog
NCOR1 nuclear receptor corepressor 1
NCSTN nicastrin
NDRG1 N-myc downstream regulated 1
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
ORC1 origin recognition complex, subunit 1
OSMR oncostatin M receptor
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PCNA proliferating cell nuclear antigen
POLA1 polymerase (DNA directed), alpha 1, catalytic subunit
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit
POLR3G polymerase (RNA) III (DNA directed) polypeptide G (32kD)
PPAP2A phosphatidic acid phosphatase type 2A
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme
PRKCA protein kinase C, alpha
PRKCB protein kinase C, beta
PRKCD protein kinase C, delta
PRKCI protein kinase C, iota
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PSAT1 phosphoserine aminotransferase 1
RAB31 RAB31, member RAS oncogene family
RAD51 RAD51 recombinase
RB1 retinoblastoma 1
RBMS1 RNA binding motif, single stranded interacting protein 1
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
REPS1 RALBP1 associated Eps domain containing 1
RFC3 replication factor C (activator 1) 3, 38kDa
RNF34 ring finger protein 34, E3 ubiquitin protein ligase
SFN stratifin
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
SNRPA1 small nuclear ribonucleoprotein polypeptide A'
SNRPF small nuclear ribonucleoprotein polypeptide F
SOD2 superoxide dismutase 2, mitochondrial
SP1 Sp1 transcription factor
STAT1 signal transducer and activator of transcription 1, 91kDa
STK4 serine/threonine kinase 4
TGFA transforming growth factor, alpha
THBS1 thrombospondin 1
TNF tumor necrosis factor
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TOP1 topoisomerase (DNA) I
TP53 tumor protein p53
TPMT thiopurine S-methyltransferase
UGT1A UDP glucuronosyltransferase 1 family, polypeptide A complex locus
UGT1A1 UDP glucuronosyltransferase 1 family, polypeptide A1
UGT1A10 UDP glucuronosyltransferase 1 family, polypeptide A10
UGT1A6 UDP glucuronosyltransferase 1 family, polypeptide A6
UGT1A7 UDP glucuronosyltransferase 1 family, polypeptide A7
UGT1A8 UDP glucuronosyltransferase 1 family, polypeptide A8
UGT1A9 UDP glucuronosyltransferase 1 family, polypeptide A9
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase
XPA xeroderma pigmentosum, complementation group A