iris synechia Gene Set

Dataset	MPO Gene-Phenotype Associations
Category	disease or phenotype associations
Type	phenotype
Description	an adhesion (synechia) of the iris to the cornea or lens of the eye that may develop from glaucoma, cataracts, uveitis, or keratitis or as a complication of surgery or trauma to the eye; synechiae may prevent or impede flow of aqueous fluid between the anterior and posterior chambers of the eye, resulting in angle closure glaucoma (Mammalian Phenotype Ontology, MP_0004222)
External Link	http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0004222
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Genes

21 gene mutations causing the iris synechia phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol	Name
ADAM17	ADAM metallopeptidase domain 17
BCAR3	breast cancer anti-estrogen resistance 3
BMP4	bone morphogenetic protein 4
CENPJ	centromere protein J
COL4A1	collagen, type IV, alpha 1
CYP1B1	cytochrome P450, family 1, subfamily B, polypeptide 1
FGF10	fibroblast growth factor 10
FOXC1	forkhead box C1
FOXE3	forkhead box E3
FOXF2	forkhead box F2
GSK3A	glycogen synthase kinase 3 alpha
LGR4	leucine-rich repeat containing G protein-coupled receptor 4
LMX1B	LIM homeobox transcription factor 1, beta
MSX2	msh homeobox 2
PAX6	paired box 6
PEX3	peroxisomal biogenesis factor 3
PPP1R13L	protein phosphatase 1, regulatory subunit 13 like
SH3PXD2B	SH3 and PX domains 2B
SIRT1	sirtuin 1
VAV2	vav 2 guanine nucleotide exchange factor
ZEB1	zinc finger E-box binding homeobox 1