iris Gene Set

Dataset GAD Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description The circular pigmented membrane behind the cornea, perforated by the pupil; the most anterior portion of the vascular tunic of the eye, it is made up of a flat bar of circular muscular fibers surrounding the pupil, a thin layer of smooth muscle fibers by which the pupil is dilated, thus regulating the amount of light entering the eye, and posteriorly two layers of pigmented epithelial cells. (BRENDA Tissue and Enzyme Source Ontology, BTO_0000653)
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Genes

3 genes associated with the disease iris in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

Symbol Name
HERC1 HECT and RLD domain containing E3 ubiquitin protein ligase family member 1
IFT54 intraflagellar transport 54
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A